Protein name:
Thymic stromal lymphopoietin ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with a receptor composed of CRLF2 and IL7R.
Function:
Cytokine that induces the release of T cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.
Subcellular Location:
Secreted
Protein Attributes:
50:
MFPFALLYVL | SVSFRKIFIL | QLVGLVLTYD | FTNCDFEKIK | AAYLSTISKD |
100:
LITYMSGTKS | TEFNNTVSCS | NRPHCLTEIQ | SLTFNPTAGC | ASLAKEMFAM |
150:
KTKAALAIWC | PGYSETQINA | TQAMKKRRKR | KVTTNKCLEQ | VSQLQGLWRR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Thymic stromal lymphopoietin
ELISA Kit for Human Thymic stromal lymphopoietin
CLIA Kit for Human Thymic stromal lymphopoietin
CLIA Kit for Human Thymic stromal lymphopoietin
Polyclonal Antibody for Human Thymic stromal lymphopoietin
Polyclonal Antibody for Human Thymic stromal lymphopoietin
Monoclonal Antibody for Human Thymic stromal lymphopoietin
Monoclonal Antibody for Human Thymic stromal lymphopoietin
Protein for Human Thymic stromal lymphopoietin
Protein for Human Thymic stromal lymphopoietin
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
Górska K, Nejman-Gryz P, Paplińska-Goryca M, et al.
References
1.
"Human thymic stromal lymphopoietin preferentially stimulates myeloid cells."
Reche P.A.
,
Soumelis V.
,
Gorman D.M.
,
Clifford T.
,
Liu M.-R.
,
Travis M.
,
Zurawski S.M.
,
Johnston J.
,
Liu Y.-J.
,
Spits H.
,
de Waal Malefyt R.
,
Kastelein R.A.
,
Bazan J.F.
J. Immunol.167:336-343(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;FUNCTION
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Testis .
4.
"Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells."
Allakhverdi Z.
,
Comeau M.R.
,
Jessup H.K.
,
Yoon B.R.
,
Brewer A.
,
Chartier S.
,
Paquette N.
,
Ziegler S.F.
,
Sarfati M.
,
Delespesse G.
J. Exp. Med.204:253-258(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN ALLERGIC INFLAMMATION;INDUCTION