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Index > Protein center > ZFP36(Gene name) > Human
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  • ZFP36 (Gene name),
  • Tristetraprolin (Protein name ),  TTP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ZFP36(G0S24;RNF162A;TIS11A;TTP);
    Protein name:
    Tristetraprolin(TTP);
    Alternative:
    Growth factor-inducible nuclear protein NUP475;G0/G1 switch regulatory protein 24;Zinc finger protein 36 homolog(Zfp-36);Protein TIS11A(TIS11);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Has been experimentally shown to be able to bind zinc.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    326
    Sequence:
    50:
    MDLTAIYESL | LSLSPDVPVP | SDHGGTESSP | GWGSSGPWSL | SPSDSSPSGV | 
    100:
    TSRLPGRSTS | LVEGRSCGWV | PPPPGFAPLA | PRLGPELSPS | PTSPTATSTT | 
    150:
    PSRYKTELCR | TFSESGRCRY | GAKCQFAHGL | GELRQANRHP | KYKTELCHKF | 
    200:
    YLQGRCPYGS | RCHFIHNPSE | DLAAPGHPPV | LRQSISFSGL | PSGRRTSPPP | 
    250:
    PGLAGPSLSS | SSFSPSSSPP | PPGDLPLSPS | AFSAAPGTPL | ARRDPTPVCC | 
    300:
    PSCRRATPIS | VWGPLGGLVR | TPSVQSLGSD | PDEYASSGSS | LGGSDSPVFE | 
    326:
    AGVFAPPQPV | AAPRRLPIFN | RISVSE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    MIM:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human TTP
    Cat.:
    E5400m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    ELISA Kit for Human TTP
    Cat.:
    E5400r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human TTP
    Cat.:
    E5400b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human TTP
    Cat.:
    E5400h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human TTP
    Cat.:
    U5400b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TTP
    Cat.:
    U5400h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TTP
    Cat.:
    U5400r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TTP
    Cat.:
    U5400m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human TTP
    Cat.:
    P5400Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TTP
    Cat.:
    P5400Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TTP
    Polyclonal Antibody for Human TTP
    Monoclonal Antibody for Human TTP
    Monoclonal Antibody for Human TTP
    Monoclonal Antibody for Human TTP
    Monoclonal Antibody for Human TTP
    Protein for Human TTP
    Protein for Human TTP
    Protein for Human TTP
    Protein for Human TTP

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The human TTP protein: sequence, alignment with related proteins, and chromosomal localization of the mouse and human genes."
      Taylor G.A. , Lai W.S. , Oakey R.J. , Seldin M.F. , Shows T.B. , Eddy R.L. Jr. , Blackshear P.J.
      Nucleic Acids Res.19:3454-3454(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Uterus.
    3. 3.
      NIEHS SNPs program
      Submitted (2004-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-37; PHE-259 AND PHE-324
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Pancreas.
    5. 5.
      "MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay."
      Stoecklin G. , Stubbs T. , Kedersha N. , Wax S. , Rigby W.F. , Blackwell T.K. , Anderson P.
      EMBO J.23:1313-1324(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-60 AND SER-186 BY MAPKAPK2;SUBCELLULAR LOCATION;RNA-BINDING;FUNCTION;MUTAGENESIS OF SER-60 AND SER-186
    6. 6.
      "Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis."
      Cao H. , Deterding L.J. , Venable J.D. , Kennington E.A. , Yates J.R. III , Tomer K.B. , Blackshear P.J.
      Biochem. J.394:285-297(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-66; SER-88; THR-92; SER-169; SER-186; SER-197; SER-218; SER-228; SER-276 AND SER-296
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-186;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin."
      Fabian M.R. , Frank F. , Rouya C. , Siddiqui N. , Lai W.S. , Karetnikov A. , Blackshear P.J. , Nagar B. , Sonenberg N.
      Nat. Struct. Mol. Biol.20:735-739(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) OF 312-326 IN COMPLEX WITH CNOT1;INTERACTION WITH CNOT1;FUNCTION;MUTAGENESIS OF ARG-315 AND PHE-319
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