TH ELISA Kit for Human(Homo sapiens) | EIAab.comTH ELISA Kit for Human(Homo sapiens)

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Index > Protein center > TH(Gene name) > Human

TH (Gene name),

Tyrosine 3-monooxygenase (Protein name ), TY3H_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TH(TYH);

Protein name:

Tyrosine 3-monooxygenase;

Alternative:

Tyrosine 3-hydroxylase(TH);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Plays an important role in the physiology of adrenergic neurons.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

528

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

528:

DSPQAVRRSL | EGVQDELDTL | AHALSAIG

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

191290

SMR:

P07101

KEGG:

hsa:7054

String:

P07101

UniGene:

Hs.435609

STRING:

9606.ENSP00000370571

Pfam:

PF00351

Uniprot:

P07101

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ELISA Kit for Human Tyrosine 3-monooxygenase

Cat.:

E1438h

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Packing:

96T

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ELISA Kit for Human Tyrosine 3-monooxygenase

Cat.:

E1438r

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96T

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ELISA Kit for Human Tyrosine 3-monooxygenase

Cat.:

E1438m

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96T

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ELISA Kit for Human Tyrosine 3-monooxygenase

Cat.:

E1438b

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MSDS:

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Packing:

96T

ELISA Kit for Human Tyrosine 3-monooxygenase

Cat.:

E1438d

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MSDS:

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Packing:

96T

CLIA Kit for Human Tyrosine 3-monooxygenase

Cat.:

U1438d

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Tyrosine 3-monooxygenase

Cat.:

U1438b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Tyrosine 3-monooxygenase

Cat.:

U1438m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Tyrosine 3-monooxygenase

Cat.:

U1438r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Tyrosine 3-monooxygenase

Cat.:

U1438h

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Manual:

Looking for manual.

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Packing:

96T

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Polyclonal Antibody for Human Tyrosine 3-monooxygenase

Cat.:

P1438Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Tyrosine 3-monooxygenase

Cat.:

P1438Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Tyrosine 3-monooxygenase

Cat.:

P1438Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Tyrosine 3-monooxygenase

Monoclonal Antibody for Human Tyrosine 3-monooxygenase

Protein for Human Tyrosine 3-monooxygenase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Isolation of a novel cDNA clone for human tyrosine hydroxylase: alternative RNA splicing produces four kinds of mRNA from a single gene."
Kaneda N. , Kobayashi K. , Ichinose H. , Kishi F. , Nakazawa A. , Kurosawa Y. , Fujita K. , Nagatsu T.
Biochem. Biophys. Res. Commun.146:971-975(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
2.

"A single human gene encoding multiple tyrosine hydroxylases with different predicted functional characteristics."
Grima B. , Lamouroux A. , Boni C. , Julien J.-F. , Javoy-Agid F. , Mallet J.
Nature326:707-711(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);ALTERNATIVE SPLICING
3.

"Isolation of a full-length cDNA clone encoding human tyrosine hydroxylase type 3."
Kobayashi K. , Kaneda N. , Ichinose H. , Kishi F. , Nakazawa A. , Kurosawa Y. , Fujita K. , Nagatsu T.
Nucleic Acids Res.15:6733-6733(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
4.

"Structure of the human tyrosine hydroxylase gene: alternative splicing from a single gene accounts for generation of four mRNA types."
Kobayashi K. , Kaneda N. , Ichinose H. , Kishi F. , Nakazawa A. , Kurosawa Y. , Fujita K. , Nagatsu T.
J. Biochem.103:907-912(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING
5.

"Characterisation of novel splicing variants of the tyrosine hydroxylase C-terminal domain in human neuroblastic tumours."
Roma J. , Saus E. , Cuadros M. , Reventos J. , Sanchez de Toledo J. , Gallego S.
Biol. Chem.388:419-426(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 5 AND 6);ALTERNATIVE SPLICING
6.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 4);VARIANT MET-112
9.

"Analysis of the 5' region of the human tyrosine hydroxylase gene: combinatorial patterns of exon splicing generate multiple regulated tyrosine hydroxylase isoforms."
le Bourdelles B. , Boularand S. , Boni C. , Horellou P. , Dumas S. , Grima B. , Mallet J.
J. Neurochem.50:988-991(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [GENOMIC DNA]
10.

"Expression of human tyrosine hydroxylase cDNA in invertebrate cells using a baculovirus vector."
Ginns E.I. , Rehavi M. , Martin B.M. , Weller M. , O'Malley K.L. , Lamarca M.E. , McAllister C.G. , Paul S.M.
J. Biol. Chem.263:7406-7410(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-30
11.

"Phosphorylation of human recombinant tyrosine hydroxylase isoforms 1 and 2: an additional phosphorylated residue in isoform 2, generated through alternative splicing."
Le Bourdelles B. , Horellou P. , Le Caer J.P. , Denefle P. , Latta M. , Haavik J. , Guibert B. , Mayaux J.F. , Mallet J.
J. Biol. Chem.266:17124-17130(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-19 AND SER-71
12.

"A rare novel deletion of the tyrosine hydroxylase gene in Parkinson disease."
Bademci G. , Edwards T.L. , Torres A.L. , Scott W.K. , Zuchner S. , Martin E.R. , Vance J.M. , Wang L.
Hum. Mutat.31:E1767-E1771(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE INVOLVEMENT IN PARKINSON DISEASE
13.

"A point mutation in the tyrosine hydroxylase gene associated with Segawa's syndrome."
Luedecke B. , Dworniczak B. , Bartholome K.
Hum. Genet.95:123-125(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN ARSEGS;VARIANT ARSEGS LYS-412
14.

"Frequent sequence variant in the human tyrosine hydroxylase gene."
Luedecke B. , Bartholome K.
Hum. Genet.95:716-716(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MET-112
15.

"Recessively inherited L-DOPA-responsive dystonia caused by a point mutation (Q381K) in the tyrosine hydroxylase gene."
Knappskog P.M. , Flatmark T. , Mallet J. , Luedecke B. , Bartholome K.
Hum. Mol. Genet.4:1209-1212(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANT ARSEGS LYS-412
16.

"Recessively inherited L-DOPA-responsive parkinsonism in infancy caused by a point mutation (L205P) in the tyrosine hydroxylase gene."
Luedecke B. , Knappskog P.M. , Clayton P.T. , Surtees R.A.H. , Clelland J.D. , Heales S.J.R. , Brand M.P. , Bartholome K. , Flatmark T.
Hum. Mol. Genet.5:1023-1028(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANT ARSEGS PRO-236
17.

"Association study of structural mutations of the tyrosine hydroxylase gene with schizophrenia and Parkinson's disease."
Kunugi H. , Kawada Y. , Hattori M. , Ueki A. , Otsuka M. , Nanko S.
Am. J. Med. Genet.81:131-133(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARSEGS PRO-236;VARIANT MET-112
18.

"Systematic search for variations in the tyrosine hydroxylase gene and their associations with schizophrenia, affective disorders, and alcoholism."
Ishiguro H. , Arinami T. , Saito T. , Akazawa S. , Enomoto M. , Mitushio H. , Fujishiro H. , Tada K. , Akimoto Y. , Mifune H. , Shiozuka S. , Hamaguchi H. , Toru M. , Shibuya H.
Am. J. Med. Genet.81:388-396(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MET-499
19.

"A common point mutation in the tyrosine hydroxylase gene in autosomal recessive L-DOPA-responsive dystonia in the Dutch population."
van den Heuvel L.P.W.J. , Luiten B. , Smeitink J.A.M. , de Rijk-van Andel J.F. , Hyland K. , Steenbergen-Spanjers G.C.H. , Janssen R.J.T. , Wevers R.A.
Hum. Genet.102:644-646(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARSEGS HIS-233
20.

"Characterization of single-nucleotide polymorphisms in coding regions of human genes."
Cargill M. , Altshuler D. , Ireland J. , Sklar P. , Ardlie K. , Patil N. , Shaw N. , Lane C.R. , Lim E.P. , Kalyanaraman N. , Nemesh J. , Ziaugra L. , Friedland L. , Rolfe A. , Warrington J. , Lipshutz R. , Daley G.Q. , Lander E.S.
Nat. Genet.22:231-238(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MET-112
21.

Cargill M. , Altshuler D. , Ireland J. , Sklar P. , Ardlie K. , Patil N. , Shaw N. , Lane C.R. , Lim E.P. , Kalyanaraman N. , Nemesh J. , Ziaugra L. , Friedland L. , Rolfe A. , Warrington J. , Lipshutz R. , Daley G.Q. , Lander E.S.
Nat. Genet.23:373-373(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
22.

"Four novel mutations in the tyrosine hydroxylase gene in patients with infantile parkinsonism."
Swaans R.J.M. , Rondot P. , Renier W.O. , Van Den Heuvel L.P.W.J. , Steenbergen-Spanjers G.C.H. , Wevers R.A.
Ann. Hum. Genet.64:25-31(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARSEGS PRO-276; MET-314; HIS-337 AND MET-494
23.

"A new tyrosine hydroxylase genotype associated with early-onset severe encephalopathy."
Giovanniello T. , Claps D. , Carducci C. , Carducci C. , Blau N. , Vigevano F. , Antonozzi I. , Leuzzi V.
J. Child Neurol.27:523-525(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARSEGS LEU-251; PHE-279 AND GLN-296;VARIANT MET-112
24.

"Myoclonus-dystonia syndrome due to tyrosine hydroxylase deficiency."
Stamelou M. , Mencacci N.E. , Cordivari C. , Batla A. , Wood N.W. , Houlden H. , Hardy J. , Bhatia K.P.
Neurology79:435-441(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARSEGS ARG-428
25.

"Tyrosine hydroxylase deficiency in Taiwanese infants."
Chi C.S. , Lee H.F. , Tsai C.R.
Pediatr. Neurol.46:77-82(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARSEGS HIS-233; SER-315 AND THR-382

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