Gene name:
TYROBP (DAP12;KARAP) ;
Protein name:
TYRO protein tyrosine kinase-binding protein ;
Alternative:
Killer-activating receptor-associated protein (KAR-associated protein) ;DNAX-activation protein 12 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer; disulfide-linked. Interacts with SIRPB1 and TREM1. Interacts with CLECSF5. Interacts with SIGLEC14. Interacts with CD300LB and CD300E. Interacts with CD300D (By similarity). Interacts with KLRC2 and KIR2DS3.
Function:
Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MGGLEPCSRL | LLLPLLLAVS | GLRPVQAQAQ | SDCSCSTVSP | GVLAGIVMGD |
100:
LVLTVLIALA | VYFLGRLVPR | GRGAAEAATR | KQRITETESP | YQELQGQRSD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Pig
Human
Bovine
Mouse
Rat
ELISA Kit for Human TYRO protein tyrosine kinase-binding protein
ELISA Kit for Human TYRO protein tyrosine kinase-binding protein
ELISA Kit for Human TYRO protein tyrosine kinase-binding protein
ELISA Kit for Human TYRO protein tyrosine kinase-binding protein
ELISA Kit for Human TYRO protein tyrosine kinase-binding protein
CLIA Kit for Human TYRO protein tyrosine kinase-binding protein
CLIA Kit for Human TYRO protein tyrosine kinase-binding protein
CLIA Kit for Human TYRO protein tyrosine kinase-binding protein
CLIA Kit for Human TYRO protein tyrosine kinase-binding protein
CLIA Kit for Human TYRO protein tyrosine kinase-binding protein
Polyclonal Antibody for Human TYRO protein tyrosine kinase-binding protein
Polyclonal Antibody for Human TYRO protein tyrosine kinase-binding protein
Polyclonal Antibody for Human TYRO protein tyrosine kinase-binding protein
Polyclonal Antibody for Human TYRO protein tyrosine kinase-binding protein
Polyclonal Antibody for Human TYRO protein tyrosine kinase-binding protein
Monoclonal Antibody for Human TYRO protein tyrosine kinase-binding protein
Monoclonal Antibody for Human TYRO protein tyrosine kinase-binding protein
Monoclonal Antibody for Human TYRO protein tyrosine kinase-binding protein
Monoclonal Antibody for Human TYRO protein tyrosine kinase-binding protein
Monoclonal Antibody for Human TYRO protein tyrosine kinase-binding protein
Protein for Human TYRO protein tyrosine kinase-binding protein
Protein for Human TYRO protein tyrosine kinase-binding protein
Protein for Human TYRO protein tyrosine kinase-binding protein
Protein for Human TYRO protein tyrosine kinase-binding protein
Protein for Human TYRO protein tyrosine kinase-binding protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
2.
"Killer activating receptor associated protein isoform b."
Cantoni C.
,
Biassoni R.
Submitted (1998-08) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue :
Lymphoid tissue .
3.
"Dendritic cells express two types of immunoreceptor DAP12 transcripts."
Begum N.A.
,
Seya T.
Submitted (2002-01) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
4.
"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N.
,
Chen X.
,
Rolfs A.
,
Halleck A.
,
Hines L.
,
Eisenstein S.
,
Koundinya M.
,
Raphael J.
,
Moreira D.
,
Kelley T.
,
LaBaer J.
,
Lin Y.
,
Phelan M.
,
Farmer A.
Submitted (2003-08) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
5.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T.
,
Suzuki Y.
,
Nishikawa T.
,
Otsuki T.
,
Sugiyama T.
,
Irie R.
,
Wakamatsu A.
,
Hayashi K.
,
Sato H.
,
Nagai K.
,
Kimura K.
,
Makita H.
,
Sekine M.
,
Obayashi M.
,
Nishi T.
,
Shibahara T.
,
Tanaka T.
,
Ishii S.
,
Yamamoto J.
,
Saito K.
,
Kawai Y.
,
Isono Y.
,
Nakamura Y.
,
Nagahari K.
,
Murakami K.
,
Yasuda T.
,
Iwayanagi T.
,
Wagatsuma M.
,
Shiratori A.
,
Sudo H.
,
Hosoiri T.
,
Kaku Y.
,
Kodaira H.
,
Kondo H.
,
Sugawara M.
,
Takahashi M.
,
Kanda K.
,
Yokoi T.
,
Furuya T.
,
Kikkawa E.
,
Omura Y.
,
Abe K.
,
Kamihara K.
,
Katsuta N.
,
Sato K.
,
Tanikawa M.
,
Yamazaki M.
,
Ninomiya K.
,
Ishibashi T.
,
Yamashita H.
,
Murakawa K.
,
Fujimori K.
,
Tanai H.
,
Kimata M.
,
Watanabe M.
,
Hiraoka S.
,
Chiba Y.
,
Ishida S.
,
Ono Y.
,
Takiguchi S.
,
Watanabe S.
,
Yosida M.
,
Hotuta T.
,
Kusano J.
,
Kanehori K.
,
Takahashi-Fujii A.
,
Hara H.
,
Tanase T.-O.
,
Nomura Y.
,
Togiya S.
,
Komai F.
,
Hara R.
,
Takeuchi K.
,
Arita M.
,
Imose N.
,
Musashino K.
,
Yuuki H.
,
Oshima A.
,
Sasaki N.
,
Aotsuka S.
,
Yoshikawa Y.
,
Matsunawa H.
,
Ichihara T.
,
Shiohata N.
,
Sano S.
,
Moriya S.
,
Momiyama H.
,
Satoh N.
,
Takami S.
,
Terashima Y.
,
Suzuki O.
,
Nakagawa S.
,
Senoh A.
,
Mizoguchi H.
,
Goto Y.
,
Shimizu F.
,
Wakebe H.
,
Hishigaki H.
,
Watanabe T.
,
Sugiyama A.
,
Takemoto M.
,
Kawakami B.
,
Yamazaki M.
,
Watanabe K.
,
Kumagai A.
,
Itakura S.
,
Fukuzumi Y.
,
Fujimori Y.
,
Komiyama M.
,
Tashiro H.
,
Tanigami A.
,
Fujiwara T.
,
Ono T.
,
Yamada K.
,
Fujii Y.
,
Ozaki K.
,
Hirao M.
,
Ohmori Y.
,
Kawabata A.
,
Hikiji T.
,
Kobatake N.
,
Inagaki H.
,
Ikema Y.
,
Okamoto S.
,
Okitani R.
,
Kawakami T.
,
Noguchi S.
,
Itoh T.
,
Shigeta K.
,
Senba T.
,
Matsumura K.
,
Nakajima Y.
,
Mizuno T.
,
Morinaga M.
,
Sasaki M.
,
Togashi T.
,
Oyama M.
,
Hata H.
,
Watanabe M.
,
Komatsu T.
,
Mizushima-Sugano J.
,
Satoh T.
,
Shirai Y.
,
Takahashi Y.
,
Nakagawa K.
,
Okumura K.
,
Nagase T.
,
Nomura N.
,
Kikuchi H.
,
Masuho Y.
,
Yamashita R.
,
Nakai K.
,
Yada T.
,
Nakamura Y.
,
Ohara O.
,
Isogai T.
,
Sugano S.
more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Umbilical cord blood .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.
"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes."
Kimura K.
,
Wakamatsu A.
,
Suzuki Y.
,
Ota T.
,
Nishikawa T.
,
Yamashita R.
,
Yamamoto J.
,
Sekine M.
,
Tsuritani K.
,
Wakaguri H.
,
Ishii S.
,
Sugiyama T.
,
Saito K.
,
Isono Y.
,
Irie R.
,
Kushida N.
,
Yoneyama T.
,
Otsuka R.
,
Kanda K.
,
Yokoi T.
,
Kondo H.
,
Wagatsuma M.
,
Murakawa K.
,
Ishida S.
,
Ishibashi T.
,
Takahashi-Fujii A.
,
Tanase T.
,
Nagai K.
,
Kikuchi H.
,
Nakai K.
,
Isogai T.
,
Sugano S.
more...
Genome Res.16:55-65(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue :
Macrophage .
8.
"The DNA sequence and biology of human chromosome 19."
Grimwood J.
,
Gordon L.A.
,
Olsen A.S.
,
Terry A.
,
Schmutz J.
,
Lamerdin J.E.
,
Hellsten U.
,
Goodstein D.
,
Couronne O.
,
Tran-Gyamfi M.
,
Aerts A.
,
Altherr M.
,
Ashworth L.
,
Bajorek E.
,
Black S.
,
Branscomb E.
,
Caenepeel S.
,
Carrano A.V.
,
Caoile C.
,
Chan Y.M.
,
Christensen M.
,
Cleland C.A.
,
Copeland A.
,
Dalin E.
,
Dehal P.
,
Denys M.
,
Detter J.C.
,
Escobar J.
,
Flowers D.
,
Fotopulos D.
,
Garcia C.
,
Georgescu A.M.
,
Glavina T.
,
Gomez M.
,
Gonzales E.
,
Groza M.
,
Hammon N.
,
Hawkins T.
,
Haydu L.
,
Ho I.
,
Huang W.
,
Israni S.
,
Jett J.
,
Kadner K.
,
Kimball H.
,
Kobayashi A.
,
Larionov V.
,
Leem S.-H.
,
Lopez F.
,
Lou Y.
,
Lowry S.
,
Malfatti S.
,
Martinez D.
,
McCready P.M.
,
Medina C.
,
Morgan J.
,
Nelson K.
,
Nolan M.
,
Ovcharenko I.
,
Pitluck S.
,
Pollard M.
,
Popkie A.P.
,
Predki P.
,
Quan G.
,
Ramirez L.
,
Rash S.
,
Retterer J.
,
Rodriguez A.
,
Rogers S.
,
Salamov A.
,
Salazar A.
,
She X.
,
Smith D.
,
Slezak T.
,
Solovyev V.
,
Thayer N.
,
Tice H.
,
Tsai M.
,
Ustaszewska A.
,
Vo N.
,
Wagner M.
,
Wheeler J.
,
Wu K.
,
Xie G.
,
Yang J.
,
Dubchak I.
,
Furey T.S.
,
DeJong P.
,
Dickson M.
,
Gordon D.
,
Eichler E.E.
,
Pennacchio L.A.
,
Richardson P.
,
Stubbs L.
,
Rokhsar D.S.
,
Myers R.M.
,
Rubin E.M.
,
Lucas S.M.
more...
Nature428:529-535(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Brain .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CLECSF5
11.
"Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts."
Paloneva J.
,
Kestilae M.
,
Wu J.
,
Salminen A.
,
Boehling T.
,
Ruotsalainen V.
,
Hakola P.
,
Bakker A.B.H.
,
Phillips J.H.
,
Pekkarinen P.
,
Lanier L.L.
,
Timonen T.
,
Peltonen L.
Nat. Genet.25:357-361(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISEASE
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TREM1
13.
"Heterogeneity of presenile dementia with bone cysts (Nasu-Hakola disease): three genetic forms."
Kondo T.
,
Takahashi K.
,
Kohara N.
,
Takahashi Y.
,
Hayashi S.
,
Takahashi H.
,
Matsuo H.
,
Yamazaki M.
,
Inoue K.
,
Miyamoto K.
,
Yamamura T.
Neurology59:1105-1107(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISEASE
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CD300E
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SIGLEC14
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CD300LB
18.
"Analysis of mouse LMIR5/CLM-7 as an activating receptor: differential regulation of LMIR5/CLM-7 in mouse versus human cells."
Yamanishi Y.
,
Kitaura J.
,
Izawa K.
,
Matsuoka T.
,
Oki T.
,
Lu Y.
,
Shibata F.
,
Yamazaki S.
,
Kumagai H.
,
Nakajima H.
,
Maeda-Yamamoto M.
,
Tybulewicz V.L.J.
,
Takai T.
,
Kitamura T.
Blood111:688-698(2008)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : INTERACTION WITH CD300LB
19.
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Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
20.
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Cited for : STRUCTURE BY NMR OF 35-67 IN COMPLEX WITH KLRC2;SUBUNIT;DISULFIDE BOND;MUTAGENESIS OF THR-54;INTERACTION WITH KLRC2 AND KIR2DS3