TYROBP ELISA Kit for Human(Homo sapiens) | EIAab.comTYROBP ELISA Kit for Human(Homo sapiens)

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Index > Protein center > TYROBP(Gene name) > Human

TYROBP (Gene name),

TYRO protein tyrosine kinase-binding protein (Protein name ), TYOBP_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TYROBP(DAP12;KARAP);

Protein name:

TYRO protein tyrosine kinase-binding protein;

Alternative:

Killer-activating receptor-associated protein(KAR-associated protein);DNAX-activation protein 12;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer; disulfide-linked. Interacts with SIRPB1 and TREM1. Interacts with CLECSF5. Interacts with SIGLEC14. Interacts with CD300LB and CD300E. Interacts with CD300D (By similarity). Interacts with KLRC2 and KIR2DS3.

Function:

Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

113

Sequence:

50:

100:

113:

VYSDLNTQRP | YYK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.515369

SMR:

O43914

MIM:

221770

STRING:

9606.ENSP00000262629

String:

O43914

KEGG:

hsa:7305

Uniprot:

O43914

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ELISA Kit for Human TYRO protein tyrosine kinase-binding protein

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ELISA Kit for Human TYRO protein tyrosine kinase-binding protein

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E12665h

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96T

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ELISA Kit for Human TYRO protein tyrosine kinase-binding protein

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ELISA Kit for Human TYRO protein tyrosine kinase-binding protein

Cat.:

E12665m

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ELISA Kit for Human TYRO protein tyrosine kinase-binding protein

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E12665r

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96T

CLIA Kit for Human TYRO protein tyrosine kinase-binding protein

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CLIA Kit for Human TYRO protein tyrosine kinase-binding protein

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CLIA Kit for Human TYRO protein tyrosine kinase-binding protein

Cat.:

U12665r

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Packing:

96T

CLIA Kit for Human TYRO protein tyrosine kinase-binding protein

Cat.:

U12665m

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Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human TYRO protein tyrosine kinase-binding protein

Cat.:

U12665h

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96T

Polyclonal Antibody for Human TYRO protein tyrosine kinase-binding protein

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P12665Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human TYRO protein tyrosine kinase-binding protein

Monoclonal Antibody for Human TYRO protein tyrosine kinase-binding protein

Protein for Human TYRO protein tyrosine kinase-binding protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells."
Lanier L.L. , Corliss B.C. , Wu J. , Leong C. , Phillips J.H.
Nature391:703-707(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
2.

"Killer activating receptor associated protein isoform b."
Cantoni C. , Biassoni R.
Submitted (1998-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Lymphoid tissue.
3.

"Dendritic cells express two types of immunoreceptor DAP12 transcripts."
Begum N.A. , Seya T.
Submitted (2002-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
4.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Umbilical cord blood.
6.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.

"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes."
Kimura K. , Wakamatsu A. , Suzuki Y. , Ota T. , Nishikawa T. , Yamashita R. , Yamamoto J. , Sekine M. , Tsuritani K. , Wakaguri H. , Ishii S. , Sugiyama T. , Saito K. , Isono Y. , Irie R. , Kushida N. , Yoneyama T. , Otsuka R. , more...
Genome Res.16:55-65(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue: Macrophage.
8.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
10.

"Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells."
Bakker A.B.H. , Baker E. , Sutherland G.R. , Phillips J.H. , Lanier L.L.
Proc. Natl. Acad. Sci. U.S.A.96:9792-9796(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CLECSF5
11.

"Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts."
Paloneva J. , Kestilae M. , Wu J. , Salminen A. , Boehling T. , Ruotsalainen V. , Hakola P. , Bakker A.B.H. , Phillips J.H. , Pekkarinen P. , Lanier L.L. , Timonen T. , Peltonen L.
Nat. Genet.25:357-361(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISEASE
12.

"Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes."
Bouchon A. , Dietrich J. , Colonna M.
J. Immunol.164:4991-4995(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TREM1
13.

"Heterogeneity of presenile dementia with bone cysts (Nasu-Hakola disease): three genetic forms."
Kondo T. , Takahashi K. , Kohara N. , Takahashi Y. , Hayashi S. , Takahashi H. , Matsuo H. , Yamazaki M. , Inoue K. , Miyamoto K. , Yamamura T.
Neurology59:1105-1107(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISEASE
14.

"TREM-1, MDL-1, and DAP12 expression is associated with a mature stage of myeloid development."
Gingras M.-C. , Lapillonne H. , Margolin J.F.
Mol. Immunol.38:817-824(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
15.

"Molecular characterization of a novel immune receptor restricted to the monocytic lineage."
Aguilar H. , Alvarez-Errico D. , Garcia-Montero A.C. , Orfao A. , Sayos J. , Lopez-Botet M.
J. Immunol.173:6703-6711(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CD300E
16.

"Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates."
Angata T. , Hayakawa T. , Yamanaka M. , Varki A. , Nakamura M.
FASEB J.20:1964-1973(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SIGLEC14
17.

"Molecular and functional characterization of CD300b, a new activating immunoglobulin receptor able to transduce signals through two different pathways."
Martinez-Barriocanal A. , Sayos J.
J. Immunol.177:2819-2830(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CD300LB
18.

"Analysis of mouse LMIR5/CLM-7 as an activating receptor: differential regulation of LMIR5/CLM-7 in mouse versus human cells."
Yamanishi Y. , Kitaura J. , Izawa K. , Matsuoka T. , Oki T. , Lu Y. , Shibata F. , Yamazaki S. , Kumagai H. , Nakajima H. , Maeda-Yamamoto M. , Tybulewicz V.L.J. , Takai T. , Kitamura T.
Blood111:688-698(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CD300LB
19.

"Large-scale proteomics analysis of the human kinome."
Oppermann F.S. , Gnad F. , Olsen J.V. , Hornberger R. , Greff Z. , Keri G. , Mann M. , Daub H.
Mol. Cell. Proteomics8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
20.

"The structural basis for intramembrane assembly of an activating immunoreceptor complex."
Call M.E. , Wucherpfennig K.W. , Chou J.J.
Nat. Immunol.11:1023-1029(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 35-67 IN COMPLEX WITH KLRC2;SUBUNIT;DISULFIDE BOND;MUTAGENESIS OF THR-54;INTERACTION WITH KLRC2 AND KIR2DS3

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