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Index > Protein center > Yy1(Gene name) > Mouse
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  • Yy1 (Gene name),
  • Transcriptional repressor protein YY1 (Protein name ),  TYY1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Yy1(Ucrbp);
    Protein name:
    Transcriptional repressor protein YY1;
    Alternative:
    NF-E1;Delta transcription factor;Yin and yang 1(YY-1);UCR-motif DNA-binding protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with YAF2 through the region encompassing the first and second zinc fingers. Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Interacts with EED and EZH2; the interactions are indicative for an association with the PRC2/EED-EZH2 complex.
    Function:
    Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; proposed to target the INO80 complex to YY1-responsive elements.
    Subcellular Location:
    Nucleus matrix Associated with the nuclear matrix. In testis, localized to heterochromatin of spermatocytes.
    Protein Attributes:
    Sequence length:
    414
    Sequence:
    50:
    MASGDTLYIA | TDGSEMPAEI | VELHEIEVET | IPVETIETTV | VGEEEEEDDD | 
    100:
    DEDGGGGDHG | GGGGGHGHAG | HHHHHHHHHH | HHPPMIALQP | LVTDDPTQVH | 
    150:
    HHQEVILVQT | REEVVGGDDS | DGLRAEDGFE | DQILIPVPAP | AGGDDDYIEQ | 
    200:
    TLVTVAAAGK | SGGGASSGGG | RVKKGGGKKS | GKKSYLGGGA | GAAGGGGADP | 
    250:
    GNKKWEQKQV | QIKTLEGEFS | VTMWSSDEKK | DIDHETVVEE | QIIGENSPPD | 
    300:
    YSEYMTGKKL | PPGGIPGIDL | SDPKQLAEFA | RMKPRKIKED | DAPRTIACPH | 
    350:
    KGCTKMFRDN | SAMRKHLHTH | GPRVHVCAEC | GKAFVESSKL | KRHQLVHTGE | 
    400:
    KPFQCTFEGC | GKRFSLDFNL | RTHVRIHTGD | RPYVCPFDGC | NKKFAQSTNL | 
    414:
    KSHILTHAKA | KNNQ
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    SMR:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Transcriptional repressor protein YY1
    Cat.:
    E11942h
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Transcriptional repressor protein YY1
    Cat.:
    E11942m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Transcriptional repressor protein YY1
    Cat.:
    U11942m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Transcriptional repressor protein YY1
    Cat.:
    U11942h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Transcriptional repressor protein YY1
    Cat.:
    P11942Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Transcriptional repressor protein YY1
    Cat.:
    P11942Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Transcriptional repressor protein YY1
    Monoclonal Antibody for Mouse Transcriptional repressor protein YY1
    Protein for Mouse Transcriptional repressor protein YY1
    Protein for Mouse Transcriptional repressor protein YY1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Cloning of a negative transcription factor that binds to the upstream conserved region of Moloney murine leukemia virus."
      Flanagan J.R. , Becker K.G. , Ennist D.L. , Gleason S.L. , Driggers P.H. , Levi B.-Z. , Appella E. , Ozato K.
      Mol. Cell. Biol.12:38-44(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Characterization of the mouse gene that encodes the delta/YY1/NF-E1/UCRBP transcription factor."
      Safrany G. , Perry R.P.
      Proc. Natl. Acad. Sci. U.S.A.90:5559-5563(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Liver.
    3. 3.
      "Delta, a transcription factor that binds to downstream elements in several polymerase II promoters, is a functionally versatile zinc finger protein."
      Hariharan N. , Kelley D.E. , Perry R.P.
      Proc. Natl. Acad. Sci. U.S.A.88:9799-9803(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary gland.
    5. 5.
      "SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer."
      Lee K.H. , Evans S. , Ruan T.Y. , Lassar A.B.
      Development131:4709-4723(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DNA-BINDING;IDENTIFICATION IN A COMPLEX WITH SMAD1 AND SMAD4
    6. 6.
      "A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair."
      Wu S. , Shi Y. , Mulligan P. , Gay F. , Landry J. , Liu H. , Lu J. , Qi H.H. , Wang W. , Nickoloff J.A. , Wu C. , Shi Y.
      Nat. Struct. Mol. Biol.14:1165-1172(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DNA REPAIR
    7. 7.
      "The PcG gene Sfmbt2 is paternally expressed in extraembryonic tissues."
      Kuzmin A. , Han Z. , Golding M.C. , Mann M.R. , Latham K.E. , Varmuza S.
      Gene Expr. Patterns8:107-116(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SFMBT2;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    8. 8.
      "Loss of YY1 impacts the heterochromatic state and meiotic double-strand breaks during mouse spermatogenesis."
      Wu S. , Hu Y.C. , Liu H. , Shi Y.
      Mol. Cell. Biol.29:6245-6256(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN SPERMATOGENESIS;SUBCELLULAR LOCATION;DISRUPTION PHENOTYPE
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