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Index > Protein center > Ubb(Gene name) > Mouse
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  • Ubb (Gene name),
  • Polyubiquitin-B (Protein name ),  UBB_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ubb;
    Protein name:
    Polyubiquitin-B;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
    Subcellular Location:
    Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    305
    Sequence:
    50:
    MQIFVKTLTG | KTITLEVEPS | DTIENVKAKI | QDKEGIPPDQ | QRLIFAGKQL | 
    100:
    EDGRTLSDYN | IQKESTLHLV | LRLRGGMQIF | VKTLTGKTIT | LEVEPSDTIE | 
    150:
    NVKAKIQDKE | GIPPDQQRLI | FAGKQLEDGR | TLSDYNIQKE | STLHLVLRLR | 
    200:
    GGMQIFVKTL | TGKTITLEVE | PSDTIENVKA | KIQDKEGIPP | DQQRLIFAGK | 
    250:
    QLEDGRTLSD | YNIQKESTLH | LVLRLRGGMQ | IFVKTLTGKT | ITLEVEPSDT | 
    300:
    IENVKAKIQD | KEGIPPDQQR | LIFAGKQLED | GRTLSDYNIQ | KESTLHLVLR | 
    305:
    LRGGY
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    SMR:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Polyubiquitin-B
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    E0164h
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    ELISA Kit for Mouse Polyubiquitin-B
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    E0164m
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    ELISA Kit for Mouse Polyubiquitin-B
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    E0164r
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    ELISA Kit for Mouse Polyubiquitin-B
    Cat.:
    E0164c
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    96T
    ELISA Kit for Mouse Polyubiquitin-B
    Cat.:
    E0164b
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    Packing:
    96T
    CLIA Kit for Mouse Polyubiquitin-B
    Cat.:
    U0164b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Polyubiquitin-B
    Cat.:
    U0164m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Polyubiquitin-B
    Cat.:
    U0164c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Polyubiquitin-B
    Cat.:
    U0164r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Polyubiquitin-B
    Cat.:
    U0164h
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Polyubiquitin-B
    Polyclonal Antibody for Mouse Polyubiquitin-B
    Cat.:
    P0164Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Polyubiquitin-B
    Cat.:
    P0164Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Polyubiquitin-B
    Polyclonal Antibody for Mouse Polyubiquitin-B
    Cat.:
    P0164Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Polyubiquitin-B
    Monoclonal Antibody for Mouse Polyubiquitin-B
    Monoclonal Antibody for Mouse Polyubiquitin-B
    Monoclonal Antibody for Mouse Polyubiquitin-B
    Monoclonal Antibody for Mouse Polyubiquitin-B
    Protein for Mouse Polyubiquitin-B
    Protein for Mouse Polyubiquitin-B
    Protein for Mouse Polyubiquitin-B
    Protein for Mouse Polyubiquitin-B
    Protein for Mouse Polyubiquitin-B

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Head.
      tissue: Kidney.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      strain: FVB/N.
      tissue: Liver.
      tissue: Mammary tumor.
    4. 4.
      "The emerging complexity of protein ubiquitination."
      Komander D.
      Biochem. Soc. Trans.37:937-953(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW;FUNCTION
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