Protein name:
Ubiquitin-conjugating enzyme E2 A ;
Alternative:
Ubiquitin carrier protein A ;RAD6 homolog A (HR6A;mHR6A) ;Ubiquitin-protein ligase A ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with RAD18 and WAC.
Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
Subcellular Location:
N/A
Protein Attributes:
50:
MSTPARRRLM | RDFKRLQEDP | PAGVSGAPSE | NNIMVWNAVI | FGPEGTPFED |
100:
GTFKLTIEFT | EEYPNKPPTV | RFVSKMFHPN | VYADGSICLD | ILQNRWSPTY |
150:
DVSSILTSIQ | SLLDEPNPNS | PANSQAAQLY | QENKREYEKR | VSAIVEQSWR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Ubiquitin-conjugating enzyme E2 A
ELISA Kit for Mouse Ubiquitin-conjugating enzyme E2 A
CLIA Kit for Mouse Ubiquitin-conjugating enzyme E2 A
CLIA Kit for Mouse Ubiquitin-conjugating enzyme E2 A
Polyclonal Antibody for Mouse Ubiquitin-conjugating enzyme E2 A
Polyclonal Antibody for Mouse Ubiquitin-conjugating enzyme E2 A
Monoclonal Antibody for Mouse Ubiquitin-conjugating enzyme E2 A
Monoclonal Antibody for Mouse Ubiquitin-conjugating enzyme E2 A
Protein for Mouse Ubiquitin-conjugating enzyme E2 A
Protein for Mouse Ubiquitin-conjugating enzyme E2 A
R&D Technical Data
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
"Isolation of mHR6A, a gene highly homologous to the male fertility gene mHR6B."
Roest H.P.
,
van Klaveren J.
,
Koken M.H.M.
,
Vermey M.
,
van Cappellen W.A.
,
Baarends W.M.
,
Hoogerbrugge J.W.
,
Bootsma D.
,
Hoeijmakers J.H.J.
,
Grootegoed J.A.
,
de Wit J.
Submitted (1998-08) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
BCBA .
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 .
tissue :
Skeletal muscle .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]