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Index > Protein center > Ubr4(Gene name) > Rat
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  • Ubr4 (Gene name),
  • E3 ubiquitin-protein ligase UBR4 (Protein name ),  UBR4_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ubr4(Rbaf600;Zubr1);
    Protein name:
    E3 ubiquitin-protein ligase UBR4;
    Alternative:
    Zinc finger UBR1-type protein 1;N-recognin-4;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with RB1 and calmodulin.
    Function:
    E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions.
    Subcellular Location:
    Membrane Multi-pass membrane protein Cytoplasm Cytoplasm cytoskeleton Nucleus Concentrates at the leading edge of membrane structures involved in actin motility.
    Protein Attributes:
    Sequence length:
    5194
    Sequence:
    50:
    MATSGGEEAA | AAAPAPGAPA | TGQDTTPGWE | VAVRPLLSAS | YSAFEMKELP | 
    100:
    QLVASVIESE | SEILHHEKQY | EPFYSSFVAL | STHYITTVCS | LIPRNQLQSV | 
    150:
    AAACKVLIEF | SLLRLENPDE | ACAVSQKHLI | LLIKGLCTGC | SRLDRTEIIT | 
    200:
    FTAMMKSAKL | PQTVKTLSDV | EDQKELASPV | SPELRQKEVQ | MNFLNQLTSV | 
    250:
    FNPRTVPSPP | ISPQALVEGE | NDEQSSTEQA | SAVKTKNVFI | AQNVASLQEL | 
    300:
    GGSEKLLRVC | LNLPYFLRYI | NRFQDAVVAN | SFFIMPATVA | DATAVRNGFH | 
    350:
    SLVIDVTMAL | DTLSLPVLEP | LNPSRLQDVT | VLSLSCLYAG | VSVATCMAIL | 
    400:
    HVGSAQQVRT | GSTSSKEEDY | ESDAATIVQK | CLEIYDMIGQ | AISSSRRAGG | 
    450:
    EHFQNFQLLG | AWCLLNSLFL | ILHLSPTALA | DKGKEKDPLA | ALRVRDILSR | 
    500:
    TKEGVGSPKL | GPGKGHQGFG | VLSVILANHA | IKLLTSLFQD | LQVEALHKGW | 
    550:
    ETDGPPAVLS | IMAQSTSTQR | VQRLIDSVPL | TNLLLTLLST | SYRKACVLQR | 
    600:
    QRKGSMSSDA | SASTDSNTYY | EDDFSSTEED | SSQDDDSEPI | LGQWFEETIS | 
    650:
    PSKEKAAPPP | PPPPPPLESS | PRVKSPSKQA | SGEKGNILAS | RKDPELFLGL | 
    700:
    ASNILNFITS | SMLNSRNNFI | RNYLSVSLSE | QHMATLASII | KEVDKDGLKG | 
    750:
    SSDEDFAAAL | YHFNHSLVTS | DLQSPNLQNT | LLQQLGVAPL | SSGPWPLYIH | 
    800:
    PQGLSVLSRL | LLIWQHKAGA | QGDPDVPECL | KVWDRFLTTM | KQSALQGVVP | 
    850:
    SETEDLNIEH | LQLLLLIFHS | FSEKGRRAIL | TTLVQSIQEL | SVNMEVQMRS | 
    900:
    APLILARLLL | IFDYLLHQYS | KAPVYLFEQV | QHNLLSPPFG | WASGSQDSSS | 
    950:
    SSRRANIPLY | HGFKEVEENW | SKHFSSDAAP | QPRFYCVLST | EASEEDLNRL | 
    1000:
    DSEACEVLFS | KLVKYDELYS | SLTALLAAGS | QLDTVKRKEN | KNMTALEACA | 
    1050:
    LQYYFLILWR | ILGILPPSKT | YMNQLAMNSP | EMSECDILHT | LRWSSRLRIS | 
    1100:
    SYVSWIKDHL | IRQGMRPEHA | GSLVELAASK | CSSVKYDVEI | VEEYFARQIS | 
    1150:
    SFCSIDCTTV | LQLHEIPSLQ | SIYTLDAAVS | KVQVSLDEHF | SKMAAETDPH | 
    1200:
    KSSEITKNLL | PATLQLIDTY | ASFTRAYLLQ | NLNEEGSTEK | PSQEKLHGFA | 
    1250:
    AVLAIGSSRC | KANTLGPTLV | QNLPSSVQSV | CESWNNINTN | EFPNIGSWRN | 
    1300:
    AFANDTIPSE | SYISAVQAAH | LGTLCGQSLP | LAASLKHALL | SLVRLTGDLI | 
    1350:
    VWSDEMNPAQ | VIRALLPLLL | ESSTESAAEI | SSNSLERILG | PAESDEFLAR | 
    1400:
    VYEKLITGCY | NILANHADPS | SGLDESVLEE | CLQYLEKQLE | SSQARKAMEE | 
    1450:
    FFSDGGELVQ | IMMATANEDL | SAKFCNRVLK | FFTKLFQLTE | KSPNPSLLHL | 
    1500:
    CGSLAQLACV | EPVRLQAWLT | RMTTSPPKDS | DQLEVIQENR | QLLQLLTTYI | 
    1550:
    VRENSQVGEG | VCAVLLGTLT | PMATDMLANG | DGTGFPELMV | VMATLASAGQ | 
    1600:
    GAGHLQLHNA | AVDWLGRCKK | YLSQKNVVEK | LNANVMHGKH | VMVLECTCHI | 
    1650:
    MSYLADVTNA | LSQSNGQGPS | HLSVDGEERA | IEVDSDWVEE | LAVEEEDSQA | 
    1700:
    EDSDEDSLCN | KLCTFTITQK | EFMNQHWYHC | HTCKMVDGVG | VCTVCAKVCH | 
    1750:
    KDHEISYAKY | GSFFCDCGAK | EDGSCLALVK | RTPSSGMSST | MKESAFQSEP | 
    1800:
    RVSESLVRHA | STSPADKAKV | TISDGKVADE | EKPKKSSLCR | TVEGCREELQ | 
    1850:
    NQANFSFAPL | VLDMLNFLMD | AIQTNFQQAS | AVGSSSRAQQ | ALSELHTVDK | 
    1900:
    VVEMTDQLMV | PTLGSQEGAF | ENVRMNYSGD | QGQTIRQLIS | AHVLRRVAMC | 
    1950:
    VLSSPHGRRQ | HLAVSHEKGK | ITVLQLSALL | KQADSSKRKL | TLTRLASAPV | 
    2000:
    PFTVLSLTGN | PCKEDYLAVC | GLKDCHVLTF | SSSGSVSDHL | VLHPQLATGN | 
    2050:
    FIIKAVWLPG | SQTELAIVTA | DFVKIYDLSV | DALSPTFYFL | LPSSKIRDVT | 
    2100:
    FLFNEEGKNI | IVIMSSAGYM | YTQLMEEASS | AQQGPFYVTN | VLEINHEDLK | 
    2150:
    DSNSQVAGGG | VSVYYSHVLQ | MLFFSYSQGK | SFAATVSRST | LEVLQLFPIN | 
    2200:
    IKSSNGGSKT | SPALCQWSEV | MNHPGLVCCV | QQTTGVPLVV | MVKPDTFLIQ | 
    2250:
    EIKTLPAKAK | IQDMVAIRHT | ACNEQQRTTM | ILLCEDGSLR | IYMANVENTS | 
    2300:
    YWLQPSLQPS | SVISIMKPVR | KRKTATITAR | TSSQVTFPID | FFEHNQQLTD | 
    2350:
    VEFGGNDLLQ | VYNAQQIKHR | LNSTGMYVAN | TKPGGFTMEI | SNNSSTMVMT | 
    2400:
    GMRIQIGTQA | IERAPSYIEI | FGRTMQLNLS | RSRWFDFPFT | REEALQADRK | 
    2450:
    LNLFIGASVD | PAGVTMIDAV | KIYGKTKEQF | GWPDEPPEDF | PSASVSSVCP | 
    2500:
    PNLNQSNSTG | DSDSAAPATT | SGTVLERLVV | SSLEALESCF | AVGPIIEKER | 
    2550:
    NKHAAQELAT | LLLSLPAPAS | VQQQSKSLLA | SLHSSRSAYH | SHKDQALLSK | 
    2600:
    AVQCLNTSSK | EGKDLDPEVF | QRLVITARSI | AVTRPNNLVH | FTESKLPQME | 
    2650:
    TEGAEEGKEP | QKQVEGDGCS | FITQLVNHFW | KLHASKPKNA | FLAPACLPGL | 
    2700:
    THIEATVNAL | VDIIHGYCTC | ELDCINTASK | IYMQMLLCPD | PAVSFSCKQA | 
    2750:
    LIRVLRPRNK | RRHVTLPSSP | RSNTPMGDKD | DDDDDDADEK | MQSSGIPDGG | 
    2800:
    HIRQESQEQS | EVDHGDFEMV | SESMVLETAE | NVNNGNPSPL | EALLAGAEGF | 
    2850:
    PPMLDIPPDA | DDETMVELAI | ALSLQQDQQG | SSSSALGLQS | LGLSGQAPSS | 
    2900:
    SSLDAGTLSD | TTASGVCACN | SSVTLSAPAS | DDEGSTAATD | GSTLRTSPAD | 
    2950:
    HGGSVGSESG | GSAVDSVAGE | HSVSGRSSAY | GDATAEGHPA | GPGSVSSSTG | 
    3000:
    AISTTTGHQE | GDGSEGEGEG | EAEGDVHTSN | RLHMVRLMLL | ERLLQTLPQL | 
    3050:
    RNVGGVRAIP | YMQVILMLTT | DLDGEDEKDK | GALDNLLAQL | IAELGMDKKD | 
    3100:
    VSKKNERSAL | NEVHLVVMRL | LSVFMSRTKS | GSKSSICESS | SLISSATAAA | 
    3150:
    LLSSGAVDYC | LHVLKSLLEY | WKGQQSEEEP | VTTSQLLKPH | TTSSPPDMSP | 
    3200:
    FFLRQYVKGH | AADVFEAYTQ | LLTEMVLRLP | YQIKKIADTS | SRIPPPVFDH | 
    3250:
    SWFYFLSEYL | MIQQTPFVRR | QVRKLLLFIC | GSKEKYRQLR | DLHTLDSHVR | 
    3300:
    GIKKLLEEQG | IFLRASVVTA | SSGSALQYDT | LISLMEHLKA | CAEIAAQRTI | 
    3350:
    NWQKFCIKDD | SVLYFLLQVS | FLVDEGVSPV | LLQLLSCALC | GSKVLAALAA | 
    3400:
    STGSSSVASS | APPAASSGQT | TTQSKSSTKK | SKKEKKEKEK | EGESSGSQED | 
    3450:
    QLCTALVNQL | NRFADKETLI | QFLRCFLLES | NSSSVRWQAH | CLTLHIYRNS | 
    3500:
    NKAQQELLLD | LMWSIWPELP | AYGRKAAQFV | DLLGYFSLKT | AQTEKKLKEY | 
    3550:
    SQKAVEILRT | QNHILTNHPN | SNIYNTLSGL | VEFDGYYLES | DPCLVCNNPE | 
    3600:
    VPFCYIKLSS | IKVDTRYTTT | QQVVKLIGSH | TISKVTVKIG | DLKRTKMVRT | 
    3650:
    INLYYNNRTV | QAIVELKNKP | ARWHKAKKVQ | LTPGQTEVKI | DLPLPIVASN | 
    3700:
    LMIEFADFYE | NYQASTETLQ | CPRCSASVPA | NPGVCGNCGE | NVYQCHKCRS | 
    3750:
    INYDEKDPFL | CNACGFCKYA | RFDFMLYAKP | CCAVDPIENE | EDRKKAVSNI | 
    3800:
    NTLLDKADRV | YHQLMGHRPQ | LENLLCKVNE | AAPEKPQEDS | GTAGGISSTS | 
    3850:
    ASVNRYILQL | AQEYCGDCKN | SFDELSKIIQ | KVFASRKELL | EYDLQQREAA | 
    3900:
    TKSSRTSVQP | TFTASQYRAL | SVLGCGHTSS | TKCYGCASAV | TEHCITLLRA | 
    3950:
    LATNPALRHI | LVSQGLIREL | FDYNLRRGAA | AIREEVRQLM | CLLTRDNPEA | 
    4000:
    TQQMNDLIIG | KVSTALKGHW | ANPDLASSLQ | YEMLLLTDSI | SKEDSCWELR | 
    4050:
    LRCALSLFLM | AVNIKTPVVV | ENITLMCLRI | LQKLIKPPAP | TSKKNKDVPV | 
    4100:
    EALTTVKPYC | NEIHAQAQLW | LKRDPKASYE | AWKKCLPIRG | VDGNGKSPSK | 
    4150:
    SELHRLYLTE | KYVWRWKQFL | SRRGKRTTPL | DLKLGHNNWL | RQVLFTPATQ | 
    4200:
    AARQAACTIV | EALASVPSRK | QQVLDLLTSY | LDELSVAGEC | AAEYLALYQK | 
    4250:
    LIASCHWKVY | LAARGVLPYV | GNLITKEIAR | LLALEEATLS | TDLQQGYALK | 
    4300:
    SLTGLLSSFV | EVESIKRHFK | SRLVGTVLNG | YLCLRKLVLQ | RTKLIDETQD | 
    4350:
    MLLEMLEDMT | TGTESETKAF | MAVCIETAKR | YNLDDYRTPV | FIFERLCSII | 
    4400:
    YPEENEVTEF | FVTLEKDPQQ | EDFLQGRMPG | NPYSSNEPGI | GPLMRDIKNK | 
    4450:
    ICQDCDLVAL | LEDDSGMELL | VNNKIISLDL | PVAEVYKKVW | CTTNEGEPMR | 
    4500:
    IVYRMRGLLG | DATEEFIESL | DSTTDEEEDE | EEVYRMAGVM | AQCGGLQCML | 
    4550:
    NRLAGVKDFK | QGRHLLTVLL | KLFSYCVKVK | VNRQQLVKLE | MNTLNVMLGT | 
    4600:
    LNLALVAEQE | SKDSGGAAVA | EQVLSIMEII | LDESNAEPLS | EDKGNLLLTG | 
    4650:
    DKDQLVMLLD | QINSTFVRSN | PSVLQGLLRI | IPYLSFGEVE | KMQILVERFK | 
    4700:
    PYCSFDKYDE | DHSGDDKVFL | DCFCKIAAGI | KNNSNGHQLK | DLILQKGITQ | 
    4750:
    SALDYMKKHI | PSAKNLDADI | WKKFLSRPAL | PFILRLLRGL | AMQHPATQVL | 
    4800:
    IGTDSITSLH | KLEQVSSDEG | IGTLAENLLE | ALREHPDVNK | KIDAARRETR | 
    4850:
    AEKKRMAMAM | RQKALGTLGM | TTNEKGQVVT | KTALLKQMEE | LIEEPGLTCC | 
    4900:
    ICREGYKFQP | TKVLGIYTFT | KRVALEEMEN | KPRKQQGYST | VSHFNIVHYD | 
    4950:
    CHLAAVRLAR | GREEWESAAL | QNANTKCNGL | LPVWGPHVPE | SAFATCLARH | 
    5000:
    NTYLQECTGQ | REPTYQLNIH | DIKLLFLRFA | MEQSFSADTG | GGGRESNIHL | 
    5050:
    IPYIIHTVLY | VLNTTRATSR | EEKNLQGFLE | QPREKWTESA | FDVDGPHYFT | 
    5100:
    ILALHVLPPE | QWKATRVEIL | RRLLVASHAR | AVAPGGATRL | TDKAVKDYSA | 
    5150:
    YRSSLLFWAL | VDLIYNMFKK | VPTSNTEGGW | SCSLAEYIRH | NDMPIYEAAD | 
    5194:
    KALKTFQEEF | MPVETFSEFL | DAAGLLSEIT | DPESFLKDLL | NSVP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat E3 ubiquitin-protein ligase UBR4
    Cat.:
    E0192h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat E3 ubiquitin-protein ligase UBR4
    Cat.:
    E0192m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat E3 ubiquitin-protein ligase UBR4
    Cat.:
    E0192r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat E3 ubiquitin-protein ligase UBR4
    Cat.:
    U0192r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat E3 ubiquitin-protein ligase UBR4
    Cat.:
    U0192m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat E3 ubiquitin-protein ligase UBR4
    Cat.:
    U0192h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat E3 ubiquitin-protein ligase UBR4
    Cat.:
    P0192Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat E3 ubiquitin-protein ligase UBR4
    Cat.:
    P0192Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat E3 ubiquitin-protein ligase UBR4
    Cat.:
    P0192Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat E3 ubiquitin-protein ligase UBR4
    Monoclonal Antibody for Rat E3 ubiquitin-protein ligase UBR4
    Monoclonal Antibody for Rat E3 ubiquitin-protein ligase UBR4
    Protein for Rat E3 ubiquitin-protein ligase UBR4
    Protein for Rat E3 ubiquitin-protein ligase UBR4
    Protein for Rat E3 ubiquitin-protein ligase UBR4

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Expression and characterization of a zinc-finger containing gene (ZUBR1) induced by bright cyclic light."
      Zhang Q. , Anderson R.E.
      Submitted (2004-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Retina.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 4841-5194
      tissue: Spleen.
    3. 3.
      "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
      Hoffert J.D. , Pisitkun T. , Wang G. , Shen R.-F. , Knepper M.A.
      Proc. Natl. Acad. Sci. U.S.A.103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1403;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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