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Index > Protein center > UCN3(Gene name) > Human
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  • UCN3 (Gene name),
  • Urocortin-3 (Protein name ),  UCN3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    UCN3(SPC);
    Protein name:
    Urocortin-3;
    Alternative:
    Urocortin III(Ucn III);Stresscopin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds with high affinity to CRF receptors 2-alpha and 2-beta.
    Function:
    Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    161
    Sequence:
    50:
    MLMPVHFLLL | LLLLLGGPRT | GLPHKFYKAK | PIFSCLNTAL | SEAEKGQWED | 
    100:
    ASLLSKRSFH | YLRSRDASSG | EEEEGKEKKT | FPISGARGGA | RGTRYRYVSQ | 
    150:
    AQPRGKPRQD | TAKSPHRTKF | TLSLDVPTNI | MNLLFNIAKA | KNLRAQAAAN | 
    161:
    AHLMAQIGRK | K
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    MIM:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Urocortin-3
    Cat.:
    E0072h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Urocortin-3
    Cat.:
    E0072m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Urocortin-3
    Cat.:
    E0072b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Urocortin-3
    Cat.:
    U0072h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Urocortin-3
    Cat.:
    U0072m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Urocortin-3
    Cat.:
    U0072b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Urocortin-3
    Polyclonal Antibody for Human Urocortin-3
    Cat.:
    P0072Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Urocortin-3
    Cat.:
    P0072Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Urocortin-3
    Monoclonal Antibody for Human Urocortin-3
    Monoclonal Antibody for Human Urocortin-3
    Protein for Human Urocortin-3
    Protein for Human Urocortin-3
    Protein for Human Urocortin-3

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    References
    1. 1.
      "Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor."
      Lewis K. , Li C. , Perrin M.H. , Blount A. , Kunitake K. , Donaldson C. , Vaughan J. , Reyes T.M. , Gulyas J. , Fischer W. , Bilezikjian L. , Rivier J. , Sawchenko P.E. , Vale W.W.
      Proc. Natl. Acad. Sci. U.S.A.98:7570-7575(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];SYNTHESIS OF UCN III;VARIANT GLY-91
    2. 2.
      "Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor."
      Hsu S.Y. , Hsueh A.J.W.
      Nat. Med.7:605-611(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLY-91
    3. 3.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLY-91
    5. 5.
      "Common and divergent structural features of a series of corticotropin releasing factor-related peptides."
      Grace C.R.R. , Perrin M.H. , Cantle J.P. , Vale W.W. , Rivier J.E. , Riek R.
      J. Am. Chem. Soc.129:16102-16114(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 120-157
    6. 6.
      "Structural basis for hormone recognition by the Human CRFR2{alpha} G protein-coupled receptor."
      Pal K. , Swaminathan K. , Xu H.E. , Pioszak A.A.
      J. Biol. Chem.285:40351-40361(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 142-157 IN COMPLEX WITH CRHR2
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