Protein name:
Vascular endothelial growth factor C (VEGF-C) ;
Alternative:
Vascular endothelial growth factor-related protein (VRP) ;Flt4 ligand (Flt4-L) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homodimer; non-covalent and antiparallel.
Function:
Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
Subcellular Location:
Secreted
Protein Attributes:
50:
MHLLCFLSLA | CSLLAAALIP | GPREAPATVA | AFESGLGFSE | AEPDGGEVKG |
100:
FEGKDLEEQL | RSVSSVDELM | SVLYPDYWKM | YKCQLRKGGW | QQPSLNMRTG |
150:
DTVKLAAAHY | NTEILKSIDN | EWRKTQCMPR | EVCIDVGKEF | GAATNTFFKP |
200:
PCVSVYRCGG | CCNSEGLQCM | NTSTGYLSKT | LFEITVPLSQ | GPKPVTISFA |
250:
NHTSCRCMSK | LDVYRQVHSI | IRRSLPATLP | QCQAANKTCP | ANYVWNNYMC |
300:
QCLAQQDFIF | YSNVEDDSSN | GFHDVCGPNK | ELDEDTCQCV | CKGGLRPSSC |
350:
GPHKELDRDS | CQCVCKNKLF | LNSCGANREF | DENTCQCVCK | RTCPRNQPLN |
400:
PGKCACECTE | NTQKCFLKGK | KFHHQTCSCY | RRPCTNRLKH | CDPGLSFSEE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
Polyclonal Antibody for Rat VEGF-C
Polyclonal Antibody for Rat VEGF-C
Polyclonal Antibody for Rat VEGF-C
Monoclonal Antibody for Rat VEGF-C
Monoclonal Antibody for Rat VEGF-C
Monoclonal Antibody for Rat VEGF-C
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;MUTAGENESIS OF CYS-152
strain :
Sprague-Dawley .
2.
"Regulation of VEGF and VEGF receptor expression in the rodent mammary gland during pregnancy, lactation, and involution."
Pepper M.S.
,
Baetens D.
,
Mandriota S.J.
,
Di Sanza C.
,
Oikemus S.
,
Lane T.F.
,
Soriano J.V.
,
Montesano R.
,
Iruela-Arispe M.L.
Dev. Dyn.218:507-524(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 153-278;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain :
Sprague-Dawley .
tissue :
Lung .