Gene name:
Flt1 (Emrk2;Flt;Vegfr1) ;
Protein name:
Vascular endothelial growth factor receptor 1 (VEGFR-1) ;
Alternative:
Fms-like tyrosine kinase 1 (FLT-1) ;Embryonic receptor kinase 2 ;Tyrosine-protein kinase receptor FLT ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with GNB2L1/RACK1.
Function:
Receptor for VEGF and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MVSCWDTAVL | PYALLGCLLL | TGYGSGSKLK | VPELSLKGTQ | HVMQAGQTLF |
100:
LKCRGEAAHS | WSLPTTVSQE | DKRLSITPPS | ACGRDNRQFC | STLTLDTAQA |
150:
NHTGLYTCRY | LPTSTSKKKK | AESSIYIFVS | DAGSPFIEMH | TDIPKLVHMT |
200:
EGRQLIIPCR | VTSPNVTVTL | KKFPFDTLTP | DGQRITWDSR | RGFIIANATY |
250:
KEIGLLNCEA | TVNGHLYQTN | YLTHRQTNTI | LDVQIRPPSP | VRLLHGQTLV |
300:
LNCTATTELN | TRVQMSWNYP | GKATKRASIR | QRIDRSHSHN | NVFHSVLKIN |
350:
NVESRDKGLY | TCRVKSGSSF | QSFNTSVHVY | EKGFISVKHR | KQPVQETTAG |
400:
RRSYRLSMKV | KAFPSPEIVW | LKDGSPATLK | SARYLVHGYS | LIIKDVTTED |
450:
AGDYTILLGI | KQSRLFKNLT | ATLIVNVKPQ | IYEKSVSSLP | SPPLYPLGSR |
500:
QVLTCTVYGI | PRPTITWLWH | PCHHNHSKER | YDFCTENEES | FILDPSSNLG |
550:
NRIESISQRM | TVIEGTNKTV | STLVVADSQT | PGIYSCRAFN | KIGTVERNIK |
600:
FYVTDVPNGF | HVSLEKMPAE | GEDLKLSCVV | NKFLYRDITW | ILLRTVNNRT |
650:
MHHSISKQKM | ATTQDYSITL | NLVIKNVSLE | DSGTYACRAR | NIYTGEDILR |
700:
KTEVLVRDSE | APHLLQNLSD | YEVSISGSTT | LDCQARGVPA | PQITWFKNNH |
750:
KIQQEPGIIL | GPGNSTLFIE | RVTEEDEGVY | RCRATNQKGA | VESAAYLTVQ |
800:
GTSDKSNLEL | ITLTCTCVAA | TLFWLLLTLF | IRKLKRSSSE | VKTDYLSIIM |
850:
DPDEVPLDEQ | CERLPYDASK | WEFARERLKL | GKSLGRGAFG | KVVQASAFGI |
900:
KKSPTCRTVA | VKMLKEGATA | SEYKALMTEL | KILTHIGHHL | NVVNLLGACT |
950:
KQGGPLMVIV | EYCKYGNLSN | YLKSKRDLFC | LNKDAALHME | LKKESLEPGL |
1000:
EQGQKPRLDS | VSSSSVTSSS | FPEDRSVSDV | EGDEDYSEIS | KQPLTMEDLI |
1050:
SYSFQVARGM | EFLSSRKCIH | RDLAARNILL | SENNVVKICD | FGLARDIYKN |
1100:
PDYVRRGDTR | LPLKWMAPES | IFDKVYSTKS | DVWSYGVLLW | EIFSLGGSPY |
1150:
PGVQMDEDFC | SRLKEGMRMR | TPEYATPEIY | QIMLDCWHKD | PKERPRFAEL |
1200:
VEKLGDLLQA | NVQQDGKDYI | PLNAILTRNS | SFTYSTPTFS | EDLFKDGFAD |
1250:
PHFHSGSSDD | VRYVNAFKFM | SLERIKTFEE | LSPNSTSMFE | DYQLDTSTLL |
1300:
GSPLLKRFTW | TETKPKASMK | IDLRIASKSK | EAGLSDLPRP | SFCFSSCGHI |
1333:
RPVQDDESEL | GKESCCSPPP | DYNSVVLYSS | PPA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Chicken
ELISA Kit for Mouse VEGFR-1
ELISA Kit for Mouse VEGFR-1
ELISA Kit for Mouse VEGFR-1
ELISA Kit for Mouse VEGFR-1
CLIA Kit for Mouse VEGFR-1
CLIA Kit for Mouse VEGFR-1
CLIA Kit for Mouse VEGFR-1
CLIA Kit for Mouse VEGFR-1
Polyclonal Antibody for Mouse VEGFR-1
Polyclonal Antibody for Mouse VEGFR-1
Polyclonal Antibody for Mouse VEGFR-1
Polyclonal Antibody for Mouse VEGFR-1
Monoclonal Antibody for Mouse VEGFR-1
Monoclonal Antibody for Mouse VEGFR-1
Monoclonal Antibody for Mouse VEGFR-1
Monoclonal Antibody for Mouse VEGFR-1
Protein for Mouse VEGFR-1
Protein for Mouse VEGFR-1
Protein for Mouse VEGFR-1
Protein for Mouse VEGFR-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
BALB/c .
tissue :
Neonatal brain .
tissue :
Placenta .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 .
tissue :
Lung .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 110-119 AND 185-191;IDENTIFICATION BY MASS SPECTROMETRY
strain :
C57BL/6 .
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE;FUNCTION IN BLOOD VESSEL DEVELOPMENT DURING EMBRYOGENESIS
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE;FUNCTION IN MACROPHAGE MIGRATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN ANGIOGENESIS
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE;FUNCTION
9.
"Vascular endothelial growth factor receptor-1 regulates postnatal angiogenesis through inhibition of the excessive activation of Akt."
Nishi J.
,
Minamino T.
,
Miyauchi H.
,
Nojima A.
,
Tateno K.
,
Okada S.
,
Orimo M.
,
Moriya J.
,
Fong G.H.
,
Sunagawa K.
,
Shibuya M.
,
Komuro I.
Circ. Res.103:261-268(2008)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN ANGIOGENESIS
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION