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Index > Protein center > VIPR1(Gene name) > Human
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  • VIPR1 (Gene name),
  • Vasoactive intestinal polypeptide receptor 1 (Protein name ),  VIPR1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    VIPR1;
    Protein name:
    Vasoactive intestinal polypeptide receptor 1(VIP-R-1);
    Alternative:
    VPAC1;Pituitary adenylate cyclase-activating polypeptide type II receptor(PACAP type II receptor;PACAP-R-2;PACAP-R2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    457
    Sequence:
    50:
    MRPPSPLPAR | WLCVLAGALA | WALGPAGGQA | ARLQEECDYV | QMIEVQHKQC | 
    100:
    LEEAQLENET | IGCSKMWDNL | TCWPATPRGQ | VVVLACPLIF | KLFSSIQGRN | 
    150:
    VSRSCTDEGW | THLEPGPYPI | ACGLDDKAAS | LDEQQTMFYG | SVKTGYTIGY | 
    200:
    GLSLATLLVA | TAILSLFRKL | HCTRNYIHMH | LFISFILRAA | AVFIKDLALF | 
    250:
    DSGESDQCSE | GSVGCKAAMV | FFQYCVMANF | FWLLVEGLYL | YTLLAVSFFS | 
    300:
    ERKYFWGYIL | IGWGVPSTFT | MVWTIARIHF | EDYGCWDTIN | SSLWWIIKGP | 
    350:
    ILTSILVNFI | LFICIIRILL | QKLRPPDIRK | SDSSPYSRLA | RSTLLLIPLF | 
    400:
    GVHYIMFAFF | PDNFKPEVKM | VFELVVGSFQ | GFVVAILYCF | LNGEVQAELR | 
    450:
    RKWRRWHLQG | VLGWNPKYRH | PSGGSNGATC | STQVSMLTRV | SPGARRSSSF | 
    457:
    QAEVSLV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    String:
    SMR:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human VIP-R-1
    Cat.:
    E15101h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human VIP-R-1
    MSDS:
    Please sign in first.
    ELISA Kit for Human VIP-R-1
    MSDS:
    Please sign in first.
    ELISA Kit for Human VIP-R-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human VIP-R-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human VIP-R-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human VIP-R-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human VIP-R-1
    Cat.:
    U15101h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human VIP-R-1
    Polyclonal Antibody for Human VIP-R-1
    Polyclonal Antibody for Human VIP-R-1
    Polyclonal Antibody for Human VIP-R-1
    Monoclonal Antibody for Human VIP-R-1
    Monoclonal Antibody for Human VIP-R-1
    Monoclonal Antibody for Human VIP-R-1
    Monoclonal Antibody for Human VIP-R-1
    Protein for Human VIP-R-1
    Protein for Human VIP-R-1
    Protein for Human VIP-R-1
    Protein for Human VIP-R-1

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    Precision
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    Linearity
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    References
    1. 1.
      "Cloning and functional expression of a human neuroendocrine vasoactive intestinal peptide receptor."
      Sreedharan S.P. , Patel D.R. , Huang J.-X. , Goetzl E.J.
      Biochem. Biophys. Res. Commun.193:546-553(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM SHORT)
      tissue: Intestine.
    2. 2.
      "Human intestinal VIP receptor: cloning and functional expression of two cDNA encoding proteins with different N-terminal domains."
      Couvineau A. , Rouyer-Fessard C. , Darmoul D. , Maoret J.J. , Carrero I. , Ogier-Denis E. , Laburthe M.
      Biochem. Biophys. Res. Commun.200:769-776(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS SHORT AND LONG);ALTERNATIVE SPLICING
      tissue: Intestine.
    3. 3.
      "Genome-wide discovery and analysis of human seven transmembrane helix receptor genes."
      Suwa M. , Sato T. , Okouchi I. , Arita M. , Futami K. , Matsumoto S. , Tsutsumi S. , Aburatani H. , Asai K. , Akiyama Y.
      Submitted (2001-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      Martin A.L. , Kaighin V.A. , Aronstam R.S.
      Submitted (2007-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT)
      tissue: Lung.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS SHORT; 3; 4 AND 5)
      tissue: Brain.
      tissue: Cerebellum.
      tissue: Lung.
      tissue: Prostate.
    6. 6.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM SHORT);VARIANT MET-341
    9. 9.
      "Molecular cloning and functional characterization of a human liver vasoactive intestinal peptide receptor."
      Gagnon A.W. , Aiyar N. , Elshourbagy N.A.
      Cell. Signal.6:321-333(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 33-457
      tissue: Liver.
    10. 10.
      "Highly conserved aspartate 68, tryptophan 73 and glycine 109 in the N-terminal extracellular domain of the human VIP receptor are essential for its ability to bind VIP."
      Couvineau A. , Gaudin P. , Maoret J.J. , Rouyer-Fessard C. , Nicole P. , Laburthe M.
      Biochem. Biophys. Res. Commun.206:246-252(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH VIP
    11. 11.
      "Predominant expression of type II vasoactive intestinal peptide receptors by human T lymphoblastoma cells: transduction of both Ca2+ and cyclic AMP signals."
      Xia M. , Sreedharan S.P. , Goetzl E.J.
      J. Clin. Immunol.16:21-30(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    12. 12.
      "Importance of conserved cysteines in the extracellular loops of human PACAP/VIP1 receptor for ligand binding and stimulation of cAMP production."
      Knudsen S.M. , Tams J.W. , Wulff B.S. , Fahrenkrug J.
      Ann. N. Y. Acad. Sci.865:259-265(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BOND
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.47 ANGSTROMS) OF 400-408 IN COMPLEX WITH MHC
    14. 14.
      "Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes."
      Beltrami A. , Rossmann M. , Fiorillo M.T. , Paladini F. , Sorrentino R. , Saenger W. , Kumar P. , Ziegler A. , Uchanska-Ziegler B.
      J. Biol. Chem.283:27189-27199(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.86 ANGSTROMS) OF 400-408 IN COMPLEX WITH MHC
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