WTIP ELISA Kit for Human(Homo sapiens) | EIAab.comWTIP ELISA Kit for Human(Homo sapiens)

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Index > Protein center > WTIP(Gene name) > Human

WTIP (Gene name),

Wilms tumor protein 1-interacting protein (Protein name ), WTIP_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

WTIP;

Protein name:

Wilms tumor protein 1-interacting protein(WT1-interacting protein);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with CD2AP and WT1.

Function:

May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype.

Subcellular Location:

Cell junction adherens junction Nucleus Translocates from cell-cell junctions to the nucleus in puromycin aminonucleoside-treated podocytes.

Protein Attributes:

Sequence length:

654

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

654:

VTEL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

A6NIX2

MIM:

614790

UniGene:

Hs.585010

STRING:

9606.ENSP00000270288

Pfam:

PF00412

KEGG:

hsa:126374

SMR:

A6NIX2

Uniprot:

A6NIX2

FOR

ELISA Kit for Human WT1-interacting protein

Cat.:

E2052h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human WT1-interacting protein

Cat.:

E2052m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human WT1-interacting protein

Cat.:

U2052h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human WT1-interacting protein

Cat.:

U2052m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human WT1-interacting protein

Cat.:

P2052Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human WT1-interacting protein

Cat.:

P2052Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human WT1-interacting protein

Protein for Human WT1-interacting protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.

"Ajuba LIM proteins are negative regulators of the Hippo signaling pathway."
Das Thakur M. , Feng Y. , Jagannathan R. , Seppa M.J. , Skeath J.B. , Longmore G.D.
Curr. Biol.20:657-662(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH LATS1; LATS2 AND SAV1
3.

"Podocyte injury induces nuclear translocation of WTIP via microtubule-dependent transport."
Kim J.H. , Konieczkowski M. , Mukherjee A. , Schechtman S. , Khan S. , Schelling J.R. , Ross M.D. , Bruggeman L.A. , Sedor J.R.
J. Biol. Chem.285:9995-10004(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
4.

"LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing."
James V. , Zhang Y. , Foxler D.E. , de Moor C.H. , Kong Y.W. , Webb T.M. , Self T.J. , Feng Y. , Lagos D. , Chu C.Y. , Rana T.M. , Morley S.J. , Longmore G.D. , Bushell M. , Sharp T.V.
Proc. Natl. Acad. Sci. U.S.A.107:12499-12504(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH EIF4E; AGO1; AGO2; DCP2 AND DDX6
5.

"Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration."
Bai S.W. , Herrera-Abreu M.T. , Rohn J.L. , Racine V. , Tajadura V. , Suryavanshi N. , Bechtel S. , Wiemann S. , Baum B. , Ridley A.J.
BMC Biol.9:54-54(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity."
Foxler D.E. , Bridge K.S. , James V. , Webb T.M. , Mee M. , Wong S.C. , Feng Y. , Constantin-Teodosiu D. , Petursdottir T.E. , Bjornsson J. , Ingvarsson S. , Ratcliffe P.J. , Longmore G.D. , Sharp T.V.
Nat. Cell Biol.14:201-208(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH EGLN2/PHD1; EGLN3/PHD3 AND VHL

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