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Index > Protein center > CX3CL1(Gene name) > Human
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  • CX3CL1 (Gene name),
  • Fractalkine (Protein name ),  X3CL1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    CX3CL1(A-152E5.2;FKN;NTT;SCYD1);
    Protein name:
    Fractalkine;
    Alternative:
    CX3C membrane-anchored chemokine;C-X3-C motif chemokine 1;Small-inducible cytokine D1;Neurotactin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
    Subcellular Location:
    Processed fractalkine Secreted
    Protein Attributes:
    Sequence length:
    397
    Sequence:
    50:
    MAPISLSWLL | RLATFCHLTV | LLAGQHHGVT | KCNITCSKMT | SKIPVALLIH | 
    100:
    YQQNQASCGK | RAIILETRQH | RLFCADPKEQ | WVKDAMQHLD | RQAAALTRNG | 
    150:
    GTFEKQIGEV | KPRTTPAAGG | MDESVVLEPE | ATGESSSLEP | TPSSQEAQRA | 
    200:
    LGTSPELPTG | VTGSSGTRLP | PTPKAQDGGP | VGTELFRVPP | VSTAATWQSS | 
    250:
    APHQPGPSLW | AEAKTSEAPS | TQDPSTQAST | ASSPAPEENA | PSEGQRVWGQ | 
    300:
    GQSPRPENSL | EREEMGPVPA | HTDAFQDWGP | GSMAHVSVVP | VSSEGTPSRE | 
    350:
    PVASGSWTPK | AEEPIHATMD | PQRLGVLITP | VPDAQAATRR | QAVGLLAFLG | 
    397:
    LLFCLGVAMF | TYQSLQGCPR | KMAGEMAEGL | RYIPRSCGSN | SYVLVPV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    KEGG:
    Pfam:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Fractalkine
    Cat.:
    E0040h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Fractalkine
    Cat.:
    E0040m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Fractalkine
    Cat.:
    E0040r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Fractalkine
    Cat.:
    U0040r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Fractalkine
    Cat.:
    U0040m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Fractalkine
    Cat.:
    U0040h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Fractalkine
    Cat.:
    P0040Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Fractalkine
    Cat.:
    P0040Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Fractalkine
    Cat.:
    P0040Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Fractalkine
    Monoclonal Antibody for Human Fractalkine
    Monoclonal Antibody for Human Fractalkine
    Protein for Human Fractalkine
    Protein for Human Fractalkine
    Protein for Human Fractalkine

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    Precision
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    Linearity
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    References
    1. 1.
      "A new class of membrane-bound chemokine with a CX3C motif."
      Bazan J.F. , Bacon K.B. , Hardiman G. , Wang W. , Soo K. , Rossi D. , Greaves D.R. , Zlotnik A. , Schall T.J.
      Nature385:640-644(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q."
      Loftus B.J. , Kim U.-J. , Sneddon V.P. , Kalush F. , Brandon R. , Fuhrmann J. , Mason T. , Crosby M.L. , Barnstead M. , Cronin L. , Mays A.D. , Cao Y. , Xu R.X. , Kang H.-L. , Mitchell S. , Eichler E.E. , Harris P.C. , Venter J.C. , more...
      Genomics60:295-308(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 4.
      "Enrichment of glycopeptides for glycan structure and attachment site identification."
      Nilsson J. , Rueetschi U. , Halim A. , Hesse C. , Carlsohn E. , Brinkmalm G. , Larson G.
      Nat. Methods6:809-811(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT SER-253 AND THR-329;STRUCTURE OF CARBOHYDRATES
      tissue: Cerebrospinal fluid.
    5. 5.
      "Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD."
      Halim A. , Nilsson J. , Ruetschi U. , Hesse C. , Larson G.
      Mol. Cell. Proteomics0:0-0(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-183; SER-253 AND THR-329;STRUCTURE OF CARBOHYDRATES;IDENTIFICATION BY MASS SPECTROMETRY
    6. 6.
      "Solution structure and dynamics of the CX3C chemokine domain of fractalkine and its interaction with an N-terminal fragment of CX3CR1."
      Mizoue L.S. , Bazan J.F. , Johnson E.C. , Handel T.M.
      Biochemistry38:1402-1414(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 25-100;SUBUNIT;INTERACTION WITH CX3CR1
    7. 7.
      "The crystal structure of the chemokine domain of fractalkine shows a novel quaternary arrangement."
      Hoover D.M. , Mizoue L.S. , Handel T.M. , Lubkowski J.
      J. Biol. Chem.275:23187-23193(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 25-98;DISULFIDE BONDS
    8. 8.
      "Structural basis of chemokine sequestration by CrmD, a poxvirus-encoded tumor necrosis factor receptor."
      Xue X. , Lu Q. , Wei H. , Wang D. , Chen D. , He G. , Huang L. , Wang H. , Wang X.
      PLoS Pathog.7:E1002162-E1002162(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 24-100 IN COMPLEX WITH POX VIRUS CRMD;FUNCTION;INTERACTION WITH VIRAL CRMD
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