Protein name:
Xanthine dehydrogenase/oxidase ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer. Interacts with BTN1A1.
Function:
Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Subcellular Location:
Cytoplasm
Peroxisome
Secreted
Protein Attributes:
50:
MTADKLVFFV | NGRKVVEKNA | DPETTLLAYL | RRKLGLSGTK | LGCGEGGCGA |
100:
CTVMLSKYDR | LQNKIVHFSA | NACLAPICSL | HHVAVTTVEG | IGSTKTRLHP |
150:
VQERIAKSHG | SQCGFCTPGI | VMSMYTLLRN | QPEPTMEEIE | NAFQGNLCRC |
200:
TGYRPILQGF | RTFARDGGCC | GGDGNNPNCC | MNQKKDHSVS | LSPSLFKPEE |
250:
FTPLDPTQEP | IFPPELLRLK | DTPRKQLRFE | GERVTWIQAS | TLKELLDLKA |
300:
QHPDAKLVVG | NTEIGIEMKF | KNMLFPMIVC | PAWIPELNSV | EHGPDGISFG |
350:
AACPLSIVEK | TLVDAVAKLP | AQKTEVFRGV | LEQLRWFAGK | QVKSVASVGG |
400:
NIITASPISD | LNPVFMASGA | KLTLVSRGTR | RTVQMDHTFF | PGYRKTLLSP |
450:
EEILLSIEIP | YSREGEYFSA | FKQASRREDD | IAKVTSGMRV | LFKPGTTEVQ |
500:
ELALCYGGMA | NRTISALKTT | QRQLSKLWKE | ELLQDVCAGL | AEELHLPPDA |
550:
PGGMVDFRCT | LTLSFFFKFY | LTVLQKLGQE | NLEDKCGKLD | PTFASATLLF |
600:
QKDPPADVQL | FQEVPKGQSE | EDMVGRPLPH | LAADMQASGE | AVYCDDIPRY |
650:
ENELSLRLVT | STRAHAKIKS | IDTSEAKKVP | GFVCFISADD | VPGSNITGIC |
700:
NDETVFAKDK | VTCVGHIIGA | VVADTPEHTQ | RAAQGVKITY | EELPAIITIE |
750:
DAIKNNSFYG | PELKIEKGDL | KKGFSEADNV | VSGEIYIGGQ | EHFYLETHCT |
800:
IAVPKGEAGE | MELFVSTQNT | MKTQSFVAKM | LGVPANRIVV | RVKRMGGGFG |
850:
GKETRSTVVS | TAVALAAYKT | GRPVRCMLDR | DEDMLITGGR | HPFLARYKVG |
900:
FMKTGTVVAL | EVDHFSNVGN | TQDLSQSIME | RALFHMDNCY | KIPNIRGTGR |
950:
LCKTNLPSNT | AFRGFGGPQG | MLIAECWMSE | VAVTCGMPAE | EVRRKNLYKE |
1000:
GDLTHFNQKL | EGFTLPRCWE | ECLASSQYHA | RKSEVDKFNK | ENCWKKRGLC |
1050:
IIPTKFGISF | TVPFLNQAGA | LLHVYTDGSV | LLTHGGTEMG | QGLHTKMVQV |
1100:
ASRALKIPTS | KIYISETSTN | TVPNTSPTAA | SVSADLNGQA | VYAACQTILK |
1150:
RLEPYKKKNP | SGSWEDWVTA | AYMDTVSLSA | TGFYRTPNLG | YSFETNSGNP |
1200:
FHYFSYGVAC | SEVEIDCLTG | DHKNLRTDIV | MDVGSSLNPA | IDIGQVEGAF |
1250:
VQGLGLFTLE | ELHYSPEGSL | HTRGPSTYKI | PAFGSIPIEF | RVSLLRDCPN |
1300:
KKAIYASKAV | GEPPLFLAAS | IFFAIKDAIR | AARAQHTGNN | VKELFRLDSP |
1333:
ATPEKIRNAC | VDKFTTLCVT | GVPENCKPWS | VRV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Rat
Mouse
Chicken
ELISA Kit for Human Xanthine dehydrogenase/oxidase
ELISA Kit for Human Xanthine dehydrogenase/oxidase
ELISA Kit for Human Xanthine dehydrogenase/oxidase
ELISA Kit for Human Xanthine dehydrogenase/oxidase
ELISA Kit for Human Xanthine dehydrogenase/oxidase
CLIA Kit for Human Xanthine dehydrogenase/oxidase
CLIA Kit for Human Xanthine dehydrogenase/oxidase
CLIA Kit for Human Xanthine dehydrogenase/oxidase
CLIA Kit for Human Xanthine dehydrogenase/oxidase
CLIA Kit for Human Xanthine dehydrogenase/oxidase
Polyclonal Antibody for Human Xanthine dehydrogenase/oxidase
Polyclonal Antibody for Human Xanthine dehydrogenase/oxidase
Polyclonal Antibody for Human Xanthine dehydrogenase/oxidase
Polyclonal Antibody for Human Xanthine dehydrogenase/oxidase
Polyclonal Antibody for Human Xanthine dehydrogenase/oxidase
Monoclonal Antibody for Human Xanthine dehydrogenase/oxidase
Monoclonal Antibody for Human Xanthine dehydrogenase/oxidase
Monoclonal Antibody for Human Xanthine dehydrogenase/oxidase
Monoclonal Antibody for Human Xanthine dehydrogenase/oxidase
Monoclonal Antibody for Human Xanthine dehydrogenase/oxidase
Protein for Human Xanthine dehydrogenase/oxidase
Protein for Human Xanthine dehydrogenase/oxidase
Protein for Human Xanthine dehydrogenase/oxidase
Protein for Human Xanthine dehydrogenase/oxidase
Protein for Human Xanthine dehydrogenase/oxidase
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .
2.
Ichida K.
Submitted (2000-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION TO 191; 231 AND 1150
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT ARG-172
tissue :
Liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ERRATUM
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];CATALYTIC ACTIVITY
tissue :
Small intestine .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS LYS-133; ARG-172; MET-235; MET-395; SER-555; ALA-584; GLN-607; ASN-617; ILE-623; VAL-646; VAL-703; MET-910; LEU-1091; THR-1109; CYS-1176 AND TRP-1296
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN XU1;VARIANT ARG-1150
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN XU1
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1074
tissue :
Milk .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF MUTANT VAL-803 IN COMPLEX WITH FAD; 2FE-2S IRON-SULFUR CENTERS; SALICYLATE; MOLYBDOPTERIN AND CALCIUM IONS;COFACTOR;CATALYTIC ACTIVITY;FUNCTION;SUBUNIT
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (3.59 ANGSTROMS) IN COMPLEX WITH FAD AND IRON-SULFUR CENTERS;TISSUE SPECIFICITY;ENZYME REGULATION;DISULFIDE BONDS
12.
"Identification of a new point mutation in the human xanthine dehydrogenase gene responsible for a case of classical type I xanthinuria."
Sakamoto N.
,
Yamamoto T.
,
Moriwaki Y.
,
Teranishi T.
,
Toyoda M.
,
Onishi Y.
,
Kuroda S.
,
Sakaguchi K.
,
Fujisawa T.
,
Maeda M.
,
Hada T.
Hum. Genet.108:279-283(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT XU1 CYS-149
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN XU1
14.
"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T.
,
Jones S.
,
Wood L.D.
,
Parsons D.W.
,
Lin J.
,
Barber T.D.
,
Mandelker D.
,
Leary R.J.
,
Ptak J.
,
Silliman N.
,
Szabo S.
,
Buckhaults P.
,
Farrell C.
,
Meeh P.
,
Markowitz S.D.
,
Willis J.
,
Dawson D.
,
Willson J.K.V.
,
Gazdar A.F.
,
Hartigan J.
,
Wu L.
,
Liu C.
,
Parmigiani G.
,
Park B.H.
,
Bachman K.E.
,
Papadopoulos N.
,
Vogelstein B.
,
Kinzler K.W.
,
Velculescu V.E.
more...
Science314:268-274(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS [LARGE SCALE ANALYSIS] PHE-763 AND GLY-791