YAP1 ELISA Kit for Chicken(Gallus gallus) | EIAab.comYAP1 ELISA Kit for Chicken(Gallus gallus)

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Index > Protein center > YAP1(Gene name) > Chicken

YAP1 (Gene name),

Yorkie homolog (Protein name ), YAP1_CHICK from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

YAP1(YAP65);

Protein name:

Yorkie homolog;

Alternative:

65 kDa Yes-associated protein(YAP65);

Organism:

Chicken (Gallus gallus).

General Annotation

Sub Unit:

Binds to the SH3 domain of the YES kinase. Also binds to other signaling molecules that contain SH3 domains including Nck, Crk and Src.

Function:

Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Plays a key role to control cell proliferation in response to cell contact. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

448

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

448:

TLEGDGMNIE | GEELMPSLQE | ALSSDILNDM | ESVLAATKPD | KESFLTWL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9031.ENSGALP00000035642

String:

P46936

KEGG:

gga:396171

Pfam:

PF00397

SMR:

P46936

UniGene:

Gga.3093

Uniprot:

P46936

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ELISA Kit for Chicken Yorkie homolog

Cat.:

E15210m

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MSDS:

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Packing:

96T

ELISA Kit for Chicken Yorkie homolog

Cat.:

E15210h

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Manual:

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96T

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ELISA Kit for Chicken Yorkie homolog

Cat.:

E15210r

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MSDS:

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96T

ELISA Kit for Chicken Yorkie homolog

Cat.:

E15210c

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MSDS:

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Packing:

96T

CLIA Kit for Chicken Yorkie homolog

Cat.:

U15210r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Chicken Yorkie homolog

Cat.:

U15210m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Chicken Yorkie homolog

Cat.:

U15210h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Chicken Yorkie homolog

Cat.:

U15210c

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MSDS:

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Packing:

96T

Polyclonal Antibody for Chicken Yorkie homolog

Cat.:

P15210Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Chicken Yorkie homolog

Cat.:

P15210Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Chicken Yorkie homolog

Cat.:

P15210Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Chicken Yorkie homolog

Monoclonal Antibody for Chicken Yorkie homolog

Protein for Chicken Yorkie homolog

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product."
Sudol M.
Oncogene9:2145-2152(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: White leghorn.

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