ZFHX3 ELISA Kit for Human(Homo sapiens) | EIAab.comZFHX3 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > ZFHX3(Gene name) > Human

ZFHX3 (Gene name),

Zinc finger homeobox protein 3 (Protein name ), ZFHX3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ZFHX3(ATBF1);

Protein name:

Zinc finger homeobox protein 3;

Alternative:

AT-binding transcription factor 1;AT motif-binding factor;Zinc finger homeodomain protein 3(ZFH-3);Alpha-fetoprotein enhancer-binding protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with FNBP3 (By similarity). Interacts with PIAS3.

Function:

Transcriptional repressor. It inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression. Down-regulates the MUC5AC promoter in gastric cancer.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

3703

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FRL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.598297

SMR:

Q15911

STRING:

9606.ENSP00000268489

MIM:

104155

String:

Q15911

Pfam:

PF00046

KEGG:

hsa:463

Uniprot:

Q15911

FOR

ELISA Kit for Human Zinc finger homeobox protein 3

Cat.:

E1065h

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human Zinc finger homeobox protein 3

Cat.:

E1065m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Zinc finger homeobox protein 3

Cat.:

U1065m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Zinc finger homeobox protein 3

Cat.:

U1065h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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Polyclonal Antibody for Human Zinc finger homeobox protein 3

Cat.:

P1065Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Zinc finger homeobox protein 3

Cat.:

P1065Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Zinc finger homeobox protein 3

Protein for Human Zinc finger homeobox protein 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning and characterization of an ATBF1 isoform that expresses in a neuronal differentiation-dependent manner."
Miura Y. , Tam T. , Ido A. , Morinaga T. , Miki T. , Hashimoto T. , Tamaoki T.
J. Biol. Chem.270:26840-26848(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A);VARIANTS ALA-72 AND ALA-777
tissue: Lung.
2.

"A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers."
Morinaga T. , Yasuda H. , Higashio K. , Tamaoki T.
Mol. Cell. Biol.11:6041-6049(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM B)
tissue: Hepatoma.
3.

"The sequence and analysis of duplication-rich human chromosome 16."
Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q."
Loftus B.J. , Kim U.-J. , Sneddon V.P. , Kalush F. , Brandon R. , Fuhrmann J. , Mason T. , Crosby M.L. , Barnstead M. , Cronin L. , Mays A.D. , Cao Y. , Xu R.X. , Kang H.-L. , Mitchell S. , Eichler E.E. , Harris P.C. , Venter J.C. , more...
Genomics60:295-308(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1-1190 (ISOFORM A);VARIANT SER-997
6.

"Positive and negative regulation of myogenic differentiation of C2C12 cells by isoforms of the multiple homeodomain zinc finger transcription factor ATBF1."
Berry F.B. , Miura Y. , Mihara K. , Kaspar P. , Sakata N. , Hashimoto-Tamaoki T. , Tamaoki T.
J. Biol. Chem.276:25057-25065(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS REGULATOR OF MYOBLASTS DIFFERENTIATION
7.

"ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3."
Nojiri S. , Joh T. , Miura Y. , Sakata N. , Nomura T. , Nakao H. , Sobue S. , Ohara H. , Asai K. , Ito M.
Biochem. Biophys. Res. Commun.314:97-103(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIAS3
8.

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-571;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
9.

"Subcellular localization of ATBF1 regulates MUC5AC transcription in gastric cancer."
Mori Y. , Kataoka H. , Miura Y. , Kawaguchi M. , Kubota E. , Ogasawara N. , Oshima T. , Tanida S. , Sasaki M. , Ohara H. , Mizoshita T. , Tatematsu M. , Asai K. , Joh T.
Int. J. Cancer121:241-247(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN GASTRIC CANCER;TISSUE SPECIFICITY
10.

"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic kidney.
11.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1197;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
12.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke."
Gudbjartsson D.F. , Holm H. , Gretarsdottir S. , Thorleifsson G. , Walters G.B. , Thorgeirsson G. , Gulcher J. , Mathiesen E.B. , Njolstad I. , Nyrnes A. , Wilsgaard T. , Hald E.M. , Hveem K. , Stoltenberg C. , Kucera G. , Stubblefield T. , Carter S. , Roden D. , more...
Nat. Genet.41:876-878(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ASSOCIATION WITH ATRIAL FIBRILLATION AND ISCHEMIC STROKE
14.

"Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry."
Benjamin E.J. , Rice K.M. , Arking D.E. , Pfeufer A. , van Noord C. , Smith A.V. , Schnabel R.B. , Bis J.C. , Boerwinkle E. , Sinner M.F. , Dehghan A. , Lubitz S.A. , D'Agostino R.B. Sr. , Lumley T. , Ehret G.B. , Heeringa J. , Aspelund T. , Newton-Cheh C. , more...
Nat. Genet.41:879-881(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ASSOCIATION WITH ATRIAL FIBRILLATION
15.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-533 AND SER-571;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
16.

"Human ALKBH4 interacts with proteins associated with transcription."
Bjornstad L.G. , Meza T.J. , Otterlei M. , Olafsrud S.M. , Meza-Zepeda L.A. , Falnes P.O.
PLoS ONE7:E49045-E49045(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ALKBH4
17.

"Solution structure of the second and third homeobox domain of AT-binding transcription factor 1 (ATBF1)."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-06) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 2241-2305 AND 2629-2698

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