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Index > Protein center > ZNF335(Gene name) > Human
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  • ZNF335 (Gene name),
  • Zinc finger protein 335 (Protein name ),  ZN335_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    ZNF335;
    Protein name:
    Zinc finger protein 335;
    Alternative:
    NRC-interacting factor 1(NIF-1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with NCOA6, but not with ligand-bound nuclear hormone receptors, including ESR1, THRA, RARA, RXRA, GCCR and PPARA.
    Function:
    May regulate transcriptional activation through NCOA6.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    1342
    Sequence:
    50:
    MEENEVESSS | DAAPGPGRPE | EPSESGLGVG | TSEAVSADSS | DAAAAPGQAE | 
    100:
    ADDSGVGQSS | DRGSRSQEEV | SESSSSADPL | PNSYLPDSSS | VSHGPVAGVT | 
    150:
    GGPPALVHSS | ALPDPNMLVS | DCTASSSDLG | SAIDKIIEST | IGPDLIQNCI | 
    200:
    TVTSAEDGGA | ETTRYLILQG | PDDGAPMTSP | MSSSTLAHSL | AAIEALADGP | 
    250:
    TSTSTCLEAQ | GGPSSPVQLP | PASGAEEPDL | QSLEAMMEVV | VVQQFKCKMC | 
    300:
    QYRSSTKATL | LRHMRERHFR | PVAAAAAAAG | KKGRLRKWST | STKSQEEEGP | 
    350:
    EEEDDDDIVD | AGAIDDLEED | SDYNPAEDEP | RGRQLRLQRP | TPSTPRPRRR | 
    400:
    PGRPRKLPRL | EISDLPDGVE | GEPLVSSQSG | QSPPEPQDPE | APSSSGPGHL | 
    450:
    VAMGKVSRTP | VEAGVSQSDA | ENAAPSCPDE | HDTLPRRRGR | PSRRFLGKKY | 
    500:
    RKYYYKSPKP | LLRPFLCRIC | GSRFLSHEDL | RFHVNSHEAG | DPQLFKCLQC | 
    550:
    SYRSRRWSSL | KEHMFNHVGS | KPYKCDECSY | TSVYRKDVIR | HAAVHSRDRK | 
    600:
    KRPDPTPKLS | SFPCPVCGRV | YPMQKRLTQH | MKTHSTEKPH | MCDKCGKSFK | 
    650:
    KRYTFKMHLL | THIQAVANRR | FKCEFCEFVC | EDKKALLNHQ | LSHVSDKPFK | 
    700:
    CSFCPYRTFR | EDFLLSHVAV | KHTGAKPFAC | EYCHFSTRHK | KNLRLHVRCR | 
    750:
    HASSFEEWGR | RHPEEPPSRR | RPFFSLQQIE | ELKQQHSAAP | GPPPSSPGPP | 
    800:
    EIPPEATTFQ | SSEAPSLLCS | DTLGGATIIY | QQGAEESTAM | ATQTALDLLL | 
    850:
    NMSAQRELGG | TALQVAVVKS | EDVEAGLASP | GGQPSPEGAT | PQVVTLHVAE | 
    900:
    PGGGAAAESQ | LGPPDLPQIT | LAPGPFGGTG | YSVITAPPME | EGTSAPGTPY | 
    950:
    SEEPAGEAAQ | AVVVSDTLKE | AGTHYIMATD | GTQLHHIELT | ADGSISFPSP | 
    1000:
    DALASGAKWP | LLQCGGLPRD | GPEPPSPAKT | HCVGDSQSSA | SSPPATSKAL | 
    1050:
    GLAVPPSPPS | AATAASKKFS | CKICAEAFPG | RAEMESHKRA | HAGPGAFKCP | 
    1100:
    DCPFSARQWP | EVRAHMAQHS | SLRPHQCSQC | SFASKNKKDL | RRHMLTHTKE | 
    1150:
    KPFACHLCGQ | RFNRNGHLKF | HIQRLHSPDG | RKSGTPTARA | PTQTPTQTII | 
    1200:
    LNSDDETLAT | LHTALQSSHG | VLGPERLQQA | LSQEHIIVAQ | EQTVTNQEEA | 
    1250:
    AYIQEITTAD | GQTVQHLVTS | DNQVQYIISQ | DGVQHLLPQE | YVVVPEGHHI | 
    1300:
    QVQEGQITHI | QYEQGAPFLQ | ESQIQYVPVS | PGQQLVTQAQ | LEAAAHSAVT | 
    1342:
    AVADAAMAQA | QGLFGTDETV | PEHIQQLQHQ | GIEYDVITLA | DD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    MIM:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Zinc finger protein 335
    Cat.:
    E1019h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human Zinc finger protein 335
    Cat.:
    E1019m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Zinc finger protein 335
    Cat.:
    E1019r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Zinc finger protein 335
    Cat.:
    U1019h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Zinc finger protein 335
    Cat.:
    U1019m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Zinc finger protein 335
    Cat.:
    U1019r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Zinc finger protein 335
    Cat.:
    P1019Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Zinc finger protein 335
    Cat.:
    P1019Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Zinc finger protein 335
    Cat.:
    P1019Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Zinc finger protein 335
    Monoclonal Antibody for Human Zinc finger protein 335
    Monoclonal Antibody for Human Zinc finger protein 335
    Protein for Human Zinc finger protein 335
    Protein for Human Zinc finger protein 335
    Protein for Human Zinc finger protein 335

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤6.2%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤7.5%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery

    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    97

    94-103

    Plasma

    98

    95-106

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    96-105%

    93-101%

    95-105%

    92-106%

    EDTA plasma(n=5)

    98-105%

    94-105%

    97-106%

    94-106%

    heparin plasma(n=5)

    96-104%

     

    97-110%

    96-111%

    96-109%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor coactivator NRC."
      Mahajan M.A. , Murray A. , Samuels H.H.
      Mol. Cell. Biol.22:6883-6894(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH NCOA6;TISSUE SPECIFICITY
      tissue: Teratocarcinoma.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT THR-294
      tissue: Kidney epithelium.
      tissue: Tongue.
    3. 3.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    5. 5.
      "Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1."
      Garapaty S. , Mahajan M.A. , Samuels H.H.
      J. Biol. Chem.283:6806-6816(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CNOT6 AND RQCD1
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1153;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      "Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation."
      Garapaty S. , Xu C.F. , Trojer P. , Mahajan M.A. , Neubert T.A. , Samuels H.H.
      J. Biol. Chem.284:7542-7552(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH ASCL2; C11ORF30; HCFC1; HSPA8; CCAR2; MATR3; MKI67; RBBP5; TUBB2A AND WDR5
    8. 8.
      "Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation."
      Yang Y.J. , Baltus A.E. , Mathew R.S. , Murphy E.A. , Evrony G.D. , Gonzalez D.M. , Wang E.P. , Marshall-Walker C.A. , Barry B.J. , Murn J. , Tatarakis A. , Mahajan M.A. , Samuels H.H. , Shi Y. , Golden J.A. , Mahajnah M. , Shenhav R. , Walsh C.A.
      Cell151:1097-1112(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MCPH10 HIS-1111;CHARACTERIZATION OF VARIANT MCPH10 HIS-1111;FUNCTION IN NEUROGENESIS;INTERACTION WITH ASCL2; CXXC1; KMT2A/MLL1; MKI67; RBBP5; SETD1A AND WDR5;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
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