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Index > Protein center > ZP3(Gene name) > Human
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  • ZP3 (Gene name),
  • Zona pellucida sperm-binding protein 3 (Protein name ),  ZP3_HUMAN from NCBI database.
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  • Gene name:
    ZP3(ZP3A;ZP3B;ZPC);
    Protein name:
    Zona pellucida sperm-binding protein 3;
    Alternative:
    ZP3A/ZP3B;Sperm receptor;Zona pellucida protein C;Zona pellucida glycoprotein 3(Zp-3);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Polymers of ZP2 and ZP3 organized into long filaments cross-linked by ZP1 homodimers.
    Function:
    The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    424
    Sequence:
    50:
    MELSYRLFIC | LLLWGSTELC | YPQPLWLLQG | GASHPETSVQ | PVLVECQEAT | 
    100:
    LMVMVSKDLF | GTGKLIRAAD | LTLGPEACEP | LVSMDTEDVV | RFEVGLHECG | 
    150:
    NSMQVTDDAL | VYSTFLLHDP | RPVGNLSIVR | TNRAEIPIEC | RYPRQGNVSS | 
    200:
    QAILPTWLPF | RTTVFSEEKL | TFSLRLMEEN | WNAEKRSPTF | HLGDAAHLQA | 
    250:
    EIHTGSHVPL | RLFVDHCVAT | PTPDQNASPY | HTIVDFHGCL | VDGLTDASSA | 
    300:
    FKVPRPGPDT | LQFTVDVFHF | ANDSRNMIYI | TCHLKVTLAE | QDPDELNKAC | 
    350:
    SFSKPSNSWF | PVEGSADICQ | CCNKGDCGTP | SHSRRQPHVM | SQWSRSASRN | 
    400:
    RRHVTEEADV | TVGPLIFLDR | RGDHEVEQWA | LPSDTSVVLL | GVGLAVVVSL | 
    424:
    TLTAVILVLT | RRCRTASHPV | SASE
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    KEGG:
    MIM:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Zona pellucida sperm-binding protein 3
    Cat.:
    E11951h
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    96T
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    ELISA Kit for Human Zona pellucida sperm-binding protein 3
    MSDS:
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    ELISA Kit for Human Zona pellucida sperm-binding protein 3
    MSDS:
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    ELISA Kit for Human Zona pellucida sperm-binding protein 3
    MSDS:
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    ELISA Kit for Human Zona pellucida sperm-binding protein 3
    MSDS:
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    ELISA Kit for Human Zona pellucida sperm-binding protein 3
    Cat.:
    E11951m
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    Packing:
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    ELISA Kit for Human Zona pellucida sperm-binding protein 3
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    E11951r
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    ELISA Kit for Human Zona pellucida sperm-binding protein 3
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    CLIA Kit for Human Zona pellucida sperm-binding protein 3
    Cat.:
    U11951m
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    Packing:
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    CLIA Kit for Human Zona pellucida sperm-binding protein 3
    MSDS:
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    CLIA Kit for Human Zona pellucida sperm-binding protein 3
    MSDS:
    Please sign in first.
    CLIA Kit for Human Zona pellucida sperm-binding protein 3
    MSDS:
    Please sign in first.
    CLIA Kit for Human Zona pellucida sperm-binding protein 3
    MSDS:
    Please sign in first.
    CLIA Kit for Human Zona pellucida sperm-binding protein 3
    MSDS:
    Please sign in first.
    CLIA Kit for Human Zona pellucida sperm-binding protein 3
    Cat.:
    U11951h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human Zona pellucida sperm-binding protein 3
    Cat.:
    U11951r
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Cat.:
    P11951Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Human Zona pellucida sperm-binding protein 3
    Protein for Human Zona pellucida sperm-binding protein 3
    Protein for Human Zona pellucida sperm-binding protein 3
    Protein for Human Zona pellucida sperm-binding protein 3
    Protein for Human Zona pellucida sperm-binding protein 3
    Protein for Human Zona pellucida sperm-binding protein 3
    Protein for Human Zona pellucida sperm-binding protein 3
    Protein for Human Zona pellucida sperm-binding protein 3
    Protein for Human Zona pellucida sperm-binding protein 3

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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ZP3A);VARIANT PRO-315
    2. 2.
      "Cloning and characterization of the human sperm receptor ligand ZP3: evidence for a second polymorphic allele with a different frequency in the Caucasian and Japanese populations."
      van Duin M. , Polman J.E. , Verkoelen C.C. , Bunschoten H. , Meyerink J.H. , Olijve W. , Aitken R.J.
      Genomics14:1064-1070(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ZP3A AND ZP3B);VARIANT PRO-315
      tissue: Ovary.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANT PRO-315
      tissue: Lung.
    4. 4.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANT PRO-315
      tissue: Brain.
    6. 6.
      "Mass spectrometry analysis of recombinant human ZP3 expressed in glycosylation-deficient CHO cells."
      Zhao M. , Boja E.S. , Hoodbhoy T. , Nawrocki J. , Kaufman J.B. , Kresge N. , Ghirlando R. , Shiloach J. , Pannell L. , Levine R.L. , Fales H.M. , Dean J.
      Biochemistry43:12090-12104(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SIGNAL SEQUENCE CLEAVAGE SITE;PYROGLUTAMATE FORMATION AT GLU-23;PROTEOLYTIC PROCESSING;DISULFIDE BONDS;GLYCOSYLATION AT ASN-125; ASN-147 AND ASN-272
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