Language:
  
[Sign in] [Register]   

EIAab logo

EIAab news detail, please contact eiaab@eiaab.com if you have any questions about online orders and payment.
Targeting Haemostatic Derangement and Endothelial Dysfunction in Dyslipidemic Rabbits: Focus on Turmeric versus Ginger Extract
Update time:2018-11-08 18:03:50   【 Font: Large  Medium Small

ABSTRACT

 

Objective: To compare between the effect of curcuminoids and ginger extract on hypercoagulability, endothelial dysfunction and some ischemic markers in dyslipidemic rabbits.

Methods: 24 male rabbits were randomly allocated into normal control (NC) group, dyslipidemic group fed atherogenic diet for 6 weeks, curcuminoids and ginger groups received their extracts as well as atherogenic diet for 6 weeks.

Results: curcuminoids and ginger extract significantly decreased serum plasminogen activator inhibitor-1 (PAI-1), prothrombin fragment (1+2) (PF1+2), endothelin-1 (ET-1), ischemia modified albumin (IMA), plasma fibrinogen (FIB) while nitric oxide (NO) showed a significant increase as compared to dyslipidemic group. Ginger extract exerted more pronounced effect than curcumionoids regarding serum PAI-1 and PF1+2. Curcuminoids, however demonstrated better effect regarding NO, ET-1 and IMA as compared to ginger extract which may refer to their antioxidant potential. Both extracts demonstrated a similar effect on plasma FIB level.

Conclusion: Ginger seems to improve haemostatic abnormalities in dyslipidemic rabbits better than curcuminoids. The latter exerted similar but weaker effects than ginger, except for their remarkable antioxidant potential and improving endothelial functions. Therefore, co-supplementation of both extracts may synergize their effects in dyslipidemia-induced haemostatic and vascular complications.
Cited products
Source:American Journal of Phytomedicine and Clinical Therapeutics      by MM El-Seweidy, MES Asker, HH Atteia
Hot Genes
ALCAM ACE KSR2 ASPRO C19orf80 Gdf5 Trap1a Atf2
Top Searches
Ubiquitin ELISA Ubiquitin-protein ligase metalloproteinase Asprosin Tumor necrosis TRAP1A vitamin d
Why choose EIAAB
Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
Further Information
About us Protein center Bank account Distributors Terms & Conditions Career eiaab.cn

Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

Twitter