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Index > Protein center > ARID4B(Gene name) > Human
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  • ARID4B (Gene name),
  • AT-rich interactive domain-containing protein 4B (Protein name ),  ARI4B_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ARID4B(BRCAA1;RBBP1L1;RBP1L1;SAP180);
    Protein name:
    AT-rich interactive domain-containing protein 4B(ARID domain-containing protein 4B);
    Alternative:
    Breast cancer-associated antigen BRCAA1;180 kDa Sin3-associated polypeptide(Sin3-associated polypeptide p180);Retinoblastoma-binding protein 1-like 1;Histone deacetylase complex subunit SAP180;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of a Sin3A corepressor complex consisting of SIN3A, SAP130, SUDS3/SAP45, SAP180, HDAC1 and HDAC2.
    Function:
    Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
    Subcellular Location:
    Nucleus Cytoplasm Cytoplasmic in breast cancer cells.
    Protein Attributes:
    Sequence length:
    1312
    Sequence:
    50:
    MKALDEPPYL | TVGTDVSAKY | RGAFCEAKIK | TAKRLVKVKV | TFRHDSSTVE | 
    100:
    VQDDHIKGPL | KVGAIVEVKN | LDGAYQEAVI | NKLTDASWYT | VVFDDGDEKT | 
    150:
    LRRSSLCLKG | ERHFAESETL | DQLPLTNPEH | FGTPVIGKKT | NRGRRSNHIP | 
    200:
    EEESSSSSSD | EDEDDRKQID | ELLGKVVCVD | YISLDKKKAL | WFPALVVCPD | 
    250:
    CSDEIAVKKD | NILVRSFKDG | KFTSVPRKDV | HEITSDTAPK | PDAVLKQAFE | 
    300:
    QALEFHKSRT | IPANWKTELK | EDSSSSEAEE | EEEEEDDEKE | KEDNSSEEEE | 
    350:
    EIEPFPEERE | NFLQQLYKFM | EDRGTPINKR | PVLGYRNLNL | FKLFRLVHKL | 
    400:
    GGFDNIESGA | VWKQVYQDLG | IPVLNSAAGY | NVKCAYKKYL | YGFEEYCRSA | 
    450:
    NIEFQMALPE | KVVNKQCKEC | ENVKEIKVKE | ENETEIKEIK | MEEERNIIPR | 
    500:
    EEKPIEDEIE | RKENIKPSLG | SKKNLLESIP | THSDQEKEVN | IKKPEDNENL | 
    550:
    DDKDDDTTRV | DESLNIKVEA | EEEKAKSGDE | TNKEEDEDDE | EAEEEEEEEE | 
    600:
    EEEDEDDDDN | NEEEEFECYP | PGMKVQVRYG | RGKNQKMYEA | SIKDSDVEGG | 
    650:
    EVLYLVHYCG | WNVRYDEWIK | ADKIVRPADK | NVPKIKHRKK | IKNKLDKEKD | 
    700:
    KDEKYSPKNC | KLRRLSKPPF | QTNPSPEMVS | KLDLTDAKNS | DTAHIKSIEI | 
    750:
    TSILNGLQAS | ESSAEDSEQE | DERGAQDMDN | NGKEESKIDH | LTNNRNDLIS | 
    800:
    KEEQNSSSLL | EENKVHADLV | ISKPVSKSPE | RLRKDIEVLS | EDTDYEEDEV | 
    850:
    TKKRKDVKKD | TTDKSSKPQI | KRGKRRYCNT | EECLKTGSPG | KKEEKAKNKE | 
    900:
    SLCMENSSNS | SSDEDEEETK | AKMTPTKKYN | GLEEKRKSLR | TTGFYSGFSE | 
    950:
    VAEKRIKLLN | NSDERLQNSR | AKDRKDVWSS | IQGQWPKKTL | KELFSDSDTE | 
    1000:
    AAASPPHPAP | EEGVAEESLQ | TVAEEESCSP | SVELEKPPPV | NVDSKPIEEK | 
    1050:
    TVEVNDRKAE | FPSSGSNSVL | NTPPTTPESP | SSVTVTEGSR | QQSSVTVSEP | 
    1100:
    LAPNQEEVRS | IKSETDSTIE | VDSVAGELQD | LQSEGNSSPA | GFDASVSSSS | 
    1150:
    SNQPEPEHPE | KACTGQKRVK | DAQGGGSSSK | KQKRSHKATV | VNNKKKGKGT | 
    1200:
    NSSDSEELSA | GESITKSQPV | KSVSTGMKSH | STKSPARTQS | PGKCGKNGDK | 
    1250:
    DPDLKEPSNR | LPKVYKWSFQ | MSDLENMTSA | ERITILQEKL | QEIRKHYLSL | 
    1300:
    KSEVASIDRR | RKRLKKKERE | SAATSSSSSS | PSSSSITAAV | MLTLAEPSMS | 
    1312:
    SASQNGMSVE | CR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    KEGG:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human ARID domain-containing protein 4B
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    ELISA Kit for Human ARID domain-containing protein 4B
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    ELISA Kit for Human ARID domain-containing protein 4B
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    Packing:
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    CLIA Kit for Human ARID domain-containing protein 4B
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human ARID domain-containing protein 4B
    MSDS:
    Please sign in first.
    CLIA Kit for Human ARID domain-containing protein 4B
    Cat.:
    U14646m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human ARID domain-containing protein 4B
    Polyclonal Antibody for Human ARID domain-containing protein 4B
    Polyclonal Antibody for Human ARID domain-containing protein 4B
    Monoclonal Antibody for Human ARID domain-containing protein 4B
    Monoclonal Antibody for Human ARID domain-containing protein 4B
    Monoclonal Antibody for Human ARID domain-containing protein 4B
    Protein for Human ARID domain-containing protein 4B
    Protein for Human ARID domain-containing protein 4B
    Protein for Human ARID domain-containing protein 4B

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "RBP1L1, a retinoblastoma-binding protein-related gene encoding an antigenic epitope abundantly expressed in human carcinomas and normal testis."
      Cao J.-N. , Gao T.-W. , Stanbridge E.J. , Irie R.
      J. Natl. Cancer Inst.93:1159-1165(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    2. 2.
      "Identification and characterization of three new components of the mSin3A corepressor complex."
      Fleischer T.C. , Yun U.J. , Ayer D.E.
      Mol. Cell. Biol.23:3456-3467(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;DOMAIN;TISSUE SPECIFICITY;IDENTIFICATION IN A MSIN3A COREPRESSOR COMPLEX WITH SIN3A; SAP130; SUDS3; ARID4B; HDAC1 AND HDAC2
    3. 3.
      "Characterization of BRCAA1 and its novel antigen epitope identification."
      Cui D. , Jin G. , Gao T.W. , Sun T. , Tian F. , Estrada G.G. , Gao H. , Sarai A.
      Cancer Epidemiol. Biomarkers Prev.13:1136-1145(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    4. 4.
      "Rheumatoid arthritis antigenic protein similar to retinoblastoma binding protein 1 (RBP1)."
      Tanaka M.
      Submitted (1999-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4)
      tissue: Synovium.
    5. 5.
      "Preparation of a set of expression-ready clones of mammalian long cDNAs encoding large proteins by the ORF trap cloning method."
      Nakajima D. , Saito K. , Yamakawa H. , Kikuno R.F. , Nakayama M. , Ohara R. , Okazaki N. , Koga H. , Nagase T. , Ohara O.
      Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    6. 6.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-651 (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-424
      tissue: Hippocampus.
      tissue: Kidney.
      tissue: Lung.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1149 (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1147-1312
      tissue: Adipose tissue.
      tissue: Testis.
    9. 9.
      "Human breast carcinoma-associated antigen isoform I."
      Cao J. , Irie R.F. , Stanbridge E.J.
      Submitted (2000-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 440-1312 (ISOFORM 1)
    10. 10.
      "Human Rb binding protein homolog gene, partial CDS."
      Liu T. , Tao J. , Zhang J. , Li W. , Ye M. , Zhou J. , Wu J. , Shen Y. , Yu M. , Chen S. , Mao M. , Chen Z.
      Submitted (1998-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 547-1312
    11. 11.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 828-1312
    12. 12.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-717;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-666; SER-675; SER-790; THR-793; THR-1150; SER-1152; SER-1153; SER-1155 AND SER-1159;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    14. 14.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-790; THR-793; SER-1014 AND THR-1026;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    16. 16.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-675; SER-778; SER-790 AND THR-793;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-276; SER-778; SER-790 AND THR-793;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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