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Index > Protein center > C5ar2(Gene name) > Rat
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  • C5ar2 (Gene name),
  • C5a anaphylatoxin chemotactic receptor 2 (Protein name ),  C5AR2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    C5ar2(C5l2;Gpr77);
    Protein name:
    C5a anaphylatoxin chemotactic receptor 2;
    Alternative:
    G-protein coupled receptor 77;Complement component 5a receptor 2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with C3 (the anaphylatoxin peptide C3a and the adipogenic hormone ASP); the interaction occurs with higher affinity for ASP, enhancing the phosphorylation and activation of GPR77, recruitment of ARRB2 to the cell surface and endocytosis of GRP77.
    Function:
    Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    343
    Sequence:
    50:
    MLNDTTSKDY | EYEYDQEQYS | DLLNVPVDCP | AGNCFSNDAY | LIVLLGLYSV | 
    100:
    IFLVGVPGNT | LLAWVTWKES | RHRLGASWFL | HLTMADLLCC | VSLPFLAVPI | 
    150:
    AQKGHWPYGT | AGCWLLSSIT | VLSMYASVLL | LTGLSGDLFL | LAFRPSWKNA | 
    200:
    DQRTCGVRVV | QVSSWMLALL | LTVPGAVYRK | LLQEHYPPRL | VCGTNYGGSV | 
    250:
    TAEVTITTVR | FLFGFLVPLV | FMASCHGILQ | RQMARRHWPL | GTAVVVGFFI | 
    300:
    CWTPFHLLRV | IIAVASSHSP | LLAWALEAEP | LVTGLALAHS | ALNPIMFLYF | 
    343:
    GRKQLCKSLQ | AACHWALRDL | QDEEESAVTK | VSTSQEMVSE | MPV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    E12838m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    E12838h
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    E12838r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    U12838r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    U12838h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    U12838m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    P12838Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    P12838Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    P12838Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat C5a anaphylatoxin chemotactic receptor 2
    Monoclonal Antibody for Rat C5a anaphylatoxin chemotactic receptor 2
    Monoclonal Antibody for Rat C5a anaphylatoxin chemotactic receptor 2
    Protein for Rat C5a anaphylatoxin chemotactic receptor 2
    Protein for Rat C5a anaphylatoxin chemotactic receptor 2
    Protein for Rat C5a anaphylatoxin chemotactic receptor 2

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    References
    1. 1.
      "Molecular cloning and expression of C5L2, a new C5a orphan receptor in sepsis."
      Gao H. , Neff T. , Younkin E. , Hoesel M. , Man Y. , Sarma V. , Guo R.-F. , Tomlins S. , Riedemann N. , Speyer C. , Zetoune F. , Ward P.
      Submitted (2004-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Long Evans.
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