Gene name:
Cdnf (Armetl1) ;
Protein name:
Cerebral dopamine neurotrophic factor ;
Alternative:
Arginine-rich protein mutated in early stage tumors-like 1 ;ARMET-like protein 1 ;Conserved dopamine neurotrophic factor ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.
Subcellular Location:
Secreted
Protein Attributes:
50:
MRCTSPAALV | TFCAGLWISN | HVLAQGLEAG | VRSRADCEVC | KEFLNRFYNS |
100:
LLTRGIDFSV | DTIEEELISF | CADTKGKENR | LCYYLGATKD | SATKILGEVT |
150:
RPMSVHMPTV | KICEKLKKMD | SQICELKYEK | KLDLESVDLW | KMRVAELKQI |
187:
LHSWGEECRA | CAEKHDYVNL | IKELAPKYVE | TRPQTEL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Rat Cerebral dopamine neurotrophic factor
ELISA Kit for Rat Cerebral dopamine neurotrophic factor
ELISA Kit for Rat Cerebral dopamine neurotrophic factor
CLIA Kit for Rat Cerebral dopamine neurotrophic factor
CLIA Kit for Rat Cerebral dopamine neurotrophic factor
CLIA Kit for Rat Cerebral dopamine neurotrophic factor
Polyclonal Antibody for Rat Cerebral dopamine neurotrophic factor
Polyclonal Antibody for Rat Cerebral dopamine neurotrophic factor
Polyclonal Antibody for Rat Cerebral dopamine neurotrophic factor
Monoclonal Antibody for Rat Cerebral dopamine neurotrophic factor
Monoclonal Antibody for Rat Cerebral dopamine neurotrophic factor
Monoclonal Antibody for Rat Cerebral dopamine neurotrophic factor
Protein for Rat Cerebral dopamine neurotrophic factor
Protein for Rat Cerebral dopamine neurotrophic factor
Protein for Rat Cerebral dopamine neurotrophic factor
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Gibbs R.A.
,
Weinstock G.M.
,
Metzker M.L.
,
Muzny D.M.
,
Sodergren E.J.
,
Scherer S.
,
Scott G.
,
Steffen D.
,
Worley K.C.
,
Burch P.E.
,
Okwuonu G.
,
Hines S.
,
Lewis L.
,
Deramo C.
,
Delgado O.
,
Dugan-Rocha S.
,
Miner G.
,
Morgan M.
,
Hawes A.
,
Gill R.
,
Holt R.A.
,
Adams M.D.
,
Amanatides P.G.
,
Baden-Tillson H.
,
Barnstead M.
,
Chin S.
,
Evans C.A.
,
Ferriera S.
,
Fosler C.
,
Glodek A.
,
Gu Z.
,
Jennings D.
,
Kraft C.L.
,
Nguyen T.
,
Pfannkoch C.M.
,
Sitter C.
,
Sutton G.G.
,
Venter J.C.
,
Woodage T.
,
Smith D.
,
Lee H.-M.
,
Gustafson E.
,
Cahill P.
,
Kana A.
,
Doucette-Stamm L.
,
Weinstock K.
,
Fechtel K.
,
Weiss R.B.
,
Dunn D.M.
,
Green E.D.
,
Blakesley R.W.
,
Bouffard G.G.
,
De Jong P.J.
,
Osoegawa K.
,
Zhu B.
,
Marra M.
,
Schein J.
,
Bosdet I.
,
Fjell C.
,
Jones S.
,
Krzywinski M.
,
Mathewson C.
,
Siddiqui A.
,
Wye N.
,
McPherson J.
,
Zhao S.
,
Fraser C.M.
,
Shetty J.
,
Shatsman S.
,
Geer K.
,
Chen Y.
,
Abramzon S.
,
Nierman W.C.
,
Havlak P.H.
,
Chen R.
,
Durbin K.J.
,
Egan A.
,
Ren Y.
,
Song X.-Z.
,
Li B.
,
Liu Y.
,
Qin X.
,
Cawley S.
,
Cooney A.J.
,
D'Souza L.M.
,
Martin K.
,
Wu J.Q.
,
Gonzalez-Garay M.L.
,
Jackson A.R.
,
Kalafus K.J.
,
McLeod M.P.
,
Milosavljevic A.
,
Virk D.
,
Volkov A.
,
Wheeler D.A.
,
Zhang Z.
,
Bailey J.A.
,
Eichler E.E.
,
Tuzun E.
,
Birney E.
,
Mongin E.
,
Ureta-Vidal A.
,
Woodwark C.
,
Zdobnov E.
,
Bork P.
,
Suyama M.
,
Torrents D.
,
Alexandersson M.
,
Trask B.J.
,
Young J.M.
,
Huang H.
,
Wang H.
,
Xing H.
,
Daniels S.
,
Gietzen D.
,
Schmidt J.
,
Stevens K.
,
Vitt U.
,
Wingrove J.
,
Camara F.
,
Mar Alba M.
,
Abril J.F.
,
Guigo R.
,
Smit A.
,
Dubchak I.
,
Rubin E.M.
,
Couronne O.
,
Poliakov A.
,
Huebner N.
,
Ganten D.
,
Goesele C.
,
Hummel O.
,
Kreitler T.
,
Lee Y.-A.
,
Monti J.
,
Schulz H.
,
Zimdahl H.
,
Himmelbauer H.
,
Lehrach H.
,
Jacob H.J.
,
Bromberg S.
,
Gullings-Handley J.
,
Jensen-Seaman M.I.
,
Kwitek A.E.
,
Lazar J.
,
Pasko D.
,
Tonellato P.J.
,
Twigger S.
,
Ponting C.P.
,
Duarte J.M.
,
Rice S.
,
Goodstadt L.
,
Beatson S.A.
,
Emes R.D.
,
Winter E.E.
,
Webber C.
,
Brandt P.
,
Nyakatura G.
,
Adetobi M.
,
Chiaromonte F.
,
Elnitski L.
,
Eswara P.
,
Hardison R.C.
,
Hou M.
,
Kolbe D.
,
Makova K.
,
Miller W.
,
Nekrutenko A.
,
Riemer C.
,
Schwartz S.
,
Taylor J.
,
Yang S.
,
Zhang Y.
,
Lindpaintner K.
,
Andrews T.D.
,
Caccamo M.
,
Clamp M.
,
Clarke L.
,
Curwen V.
,
Durbin R.M.
,
Eyras E.
,
Searle S.M.
,
Cooper G.M.
,
Batzoglou S.
,
Brudno M.
,
Sidow A.
,
Stone E.A.
,
Payseur B.A.
,
Bourque G.
,
Lopez-Otin C.
,
Puente X.S.
,
Chakrabarti K.
,
Chatterji S.
,
Dewey C.
,
Pachter L.
,
Bray N.
,
Yap V.B.
,
Caspi A.
,
Tesler G.
,
Pevzner P.A.
,
Haussler D.
,
Roskin K.M.
,
Baertsch R.
,
Clawson H.
,
Furey T.S.
,
Hinrichs A.S.
,
Karolchik D.
,
Kent W.J.
,
Rosenbloom K.R.
,
Trumbower H.
,
Weirauch M.
,
Cooper D.N.
,
Stenson P.D.
,
Ma B.
,
Brent M.
,
Arumugam M.
,
Shteynberg D.
,
Copley R.R.
,
Taylor M.S.
,
Riethman H.
,
Mudunuri U.
,
Peterson J.
,
Guyer M.
,
Felsenfeld A.
,
Old S.
,
Mockrin S.
,
Collins F.S.
more...
Nature428:493-521(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Brown Norway .
2.
"Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo."
Lindholm P.
,
Voutilainen M.H.
,
Lauren J.
,
Peraenen J.
,
Leppaenen V.-M.
,
Andressoo J.-O.
,
Lindahl M.
,
Janhunen S.
,
Kalkkinen N.
,
Timmusk T.
,
Tuominen R.K.
,
Saarma M.
Nature448:73-77(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION