Protein name:
Frizzled-1 (Fz-1;cFz-1) ;
Alternative:
Organism:
Chicken (Gallus gallus).
General Annotation
Function:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Subcellular Location:
Membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MAERRGPAGG | GSGEVGGGRR | AGGDRCPRRP | PALPLLLLLW | AAALPAGGQP |
100:
AAQPAALSER | GISIPDHGYC | QPISIPLCTD | IAYNQTIMPN | LLGHTNQEDA |
150:
GLEVHQFYPL | VKVQCSAELK | FFLCSMYAPV | CTVLEQALPP | CRSLCERARQ |
200:
GCEALMNKFG | FQWPDTLRCE | KFPVHGAGEL | CVGQNASERG | TPTPALRPES |
250:
WTSNPHRGGG | AGGSGPGEAR | GRFSCPRALK | VPSYLNYRFL | GEKDCGAPCE |
300:
PGRLYGLMYF | GPEELRFSRT | WIGIWSVLCC | ASTLFTVLTY | LVDMKRFSYP |
350:
ERPIIFLSGC | YTAVAVAYIA | GFLLEERVVC | NERFAEDGSR | TVAQGTKREG |
400:
CTILFMMLYF | FGMASSIWWV | ILSLTWFLAA | GMKWGHEAIE | ANSQYFHLAA |
450:
WAVPAIKTIT | ILALGQVDGD | VLSGVCFVGI | NNVDALRGFV | LAPLFVYLFI |
500:
GTSFLLAGFV | SLFRIRTIMK | HDGTKTEKLE | KLMVRIGIFS | VLYTVPATIV |
550:
IACYFYEQAF | REQWERSWVT | QSCKSYAIPC | PNNHSSHHPP | MSPDFTVFMI |
592:
KYLMTLIVGI | TSGFWIWSGK | TLNSWRKFYT | RLTNSKQGET | TV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Mouse
Rat
Human
ELISA Kit for Chicken Fz-1
ELISA Kit for Chicken Fz-1
ELISA Kit for Chicken Fz-1
ELISA Kit for Chicken Fz-1
CLIA Kit for Chicken Fz-1
CLIA Kit for Chicken Fz-1
CLIA Kit for Chicken Fz-1
CLIA Kit for Chicken Fz-1
Polyclonal Antibody for Chicken Fz-1
Polyclonal Antibody for Chicken Fz-1
Polyclonal Antibody for Chicken Fz-1
Polyclonal Antibody for Chicken Fz-1
Monoclonal Antibody for Chicken Fz-1
Monoclonal Antibody for Chicken Fz-1
Monoclonal Antibody for Chicken Fz-1
Monoclonal Antibody for Chicken Fz-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Limb bud .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 307-592