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Index > Protein center > JUN(Gene name) > Bovine
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  • JUN (Gene name),
  • Transcription factor AP-1 (Protein name ),  JUN_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    JUN;
    Protein name:
    Transcription factor AP-1;
    Alternative:
    Proto-oncogene c-Jun;Activator protein 1(AP1);V-jun avian sarcoma virus 17 oncogene homolog;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Heterodimer with either FOS or BATF3 or ATF7 (By similarity). The ATF7/JUN heterodimer is essential for ATF7 transactivation activity (By similarity). Interacts with HIVEP3. Interacts with MYBBP1A, SP1, SPIB and TCF20. Interacts with COPS5; the interaction leads indirectly to its phosphorylation. Interacts with DSIPI; the interaction inhibits the binding of active AP1 to its target DNA. Component of the SMAD3/SMAD4/JUN/FOS/complex which forms at the AP1 promoter site. The SMAD3/SMAD4 heterodimer acts syngernistically with the JUN/FOS heterodimer to activate transcription in response to TGF-beta. Interacts (via its basic DNA binding and leucine zipper domains) with SMAD3 (via an N-terminal domain); the interaction is required for TGF-beta-mediated transactivation of the SMAD3/SMAD4/JUN/FOS/complex. Interacts with RNF187 and HIPK3.
    Function:
    Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    335
    Sequence:
    50:
    MTAKMETTFY | DDALNASFLQ | SESGAYGYSN | PKILKQSMTL | NLADPVGSLK | 
    100:
    PHLRAKNSDL | LTSPDVGLLK | LASPELERLI | IQSSNGHITT | TPTPTQFLCP | 
    150:
    KNVTDEQEGF | AEGFVRALAE | LHSQNTLPSV | TSAAQPVSGA | GLVAPAVASV | 
    200:
    AGGSGSGGFS | ASLHSEPPVY | ANLSNFNPGS | LSSGGGAPSY | GAAGLAFPAQ | 
    250:
    PQQQQQQPPQ | PPHHLPQQIP | VQHPRLQALK | EEPQTVPEMP | GETPPLSPID | 
    300:
    MESQERIKAE | RKRMRNRIAA | SKCRKRKLER | IARLEEKVKT | LKAQNSELAS | 
    335:
    TANMLREQVA | QLKQKVMNHV | NSGCQLMLTQ | QLQTF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    UniGene:
    String:
    Uniprot:
     
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    ELISA Kit for Bovine Transcription factor AP-1
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    ELISA Kit for Bovine Transcription factor AP-1
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    ELISA Kit for Bovine Transcription factor AP-1
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    E1292h
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    ELISA Kit for Bovine Transcription factor AP-1
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    E1292b
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    ELISA Kit for Bovine Transcription factor AP-1
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    ELISA Kit for Bovine Transcription factor AP-1
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    CLIA Kit for Bovine Transcription factor AP-1
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    U1292c
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    96T
    CLIA Kit for Bovine Transcription factor AP-1
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    U1292p
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    Packing:
    96T
    CLIA Kit for Bovine Transcription factor AP-1
    Cat.:
    U1292b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine Transcription factor AP-1
    Cat.:
    U1292h
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Bovine Transcription factor AP-1
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    U1292r
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine Transcription factor AP-1
    Cat.:
    U1292m
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    MSDS:
    Please sign in first.
    Packing:
    96T
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    Polyclonal Antibody for Bovine Transcription factor AP-1
    Polyclonal Antibody for Bovine Transcription factor AP-1
    Polyclonal Antibody for Bovine Transcription factor AP-1
    Cat.:
    P1292Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Transcription factor AP-1
    Polyclonal Antibody for Bovine Transcription factor AP-1
    Cat.:
    P1292Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Transcription factor AP-1
    Cat.:
    P1292Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Transcription factor AP-1
    Monoclonal Antibody for Bovine Transcription factor AP-1
    Monoclonal Antibody for Bovine Transcription factor AP-1
    Monoclonal Antibody for Bovine Transcription factor AP-1
    Monoclonal Antibody for Bovine Transcription factor AP-1
    Monoclonal Antibody for Bovine Transcription factor AP-1
    Protein for Bovine Transcription factor AP-1
    Protein for Bovine Transcription factor AP-1
    Protein for Bovine Transcription factor AP-1
    Protein for Bovine Transcription factor AP-1
    Protein for Bovine Transcription factor AP-1
    Protein for Bovine Transcription factor AP-1

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    References
    1. 1.
      "The genome sequence of taurine cattle: a window to ruminant biology and evolution."
      The bovine genome sequencing and analysis consortium
      Science324:522-528(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Hereford.
    2. 2.
      "Stimulation of c-fos and c-jun mRNA in bovine luteal cells."
      Davis J.S. , Fong H.W. , Westfall S.W.
      Submitted (1998-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-110
      tissue: Brain.
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