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Index > Protein center > SFPQ(Gene name) > Human
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  • SFPQ (Gene name),
  • Splicing factor, proline- and glutamine-rich (Protein name ),  SFPQ_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SFPQ(PSF);
    Protein name:
    Splicing factor, proline- and glutamine-rich;
    Alternative:
    DNA-binding p52/p100 complex, 100 kDa subunit;100 kDa DNA-pairing protein(hPOMp100);Polypyrimidine tract-binding protein-associated-splicing factor(PSF;PTB-associated-splicing factor);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with PSPC1 (By similarity). Monomer and component of the SFPQ-NONO complex, which is probably a heterotetramer of two 52 kDa (NONO) and two 100 kDa (SFPQ) subunits. SFPQ is a component of spliceosome and U5.4/6 snRNP complexes. Interacts with SNRPA/U1A. Component of a snRNP-free complex with SNRPA/U1A. Part of complex consisting of SFPQ, NONO and MATR3. Interacts with polypyrimidine tract-binding protein 1/PTB. Part of a complex consisting of SFPQ, NONO and NR5A1. Interacts with RXRA, probably THRA, and SIN3A. Interacts with TOP1. Part of a complex consisting of SFPQ, NONO and TOP1. Interacts with SNRNP70 in apoptotic cells (By similarity). Interacts with RNF43. Interacts with PITX3 and NR4A2/NURR1.
    Function:
    DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as an heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. May be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs. SFPQ may be involved in homologous DNA pairing; in vitro, promotes the invasion of ssDNA between a duplex DNA and produces a D-loop formation. The SFPQ-NONO heteromer may be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1; in vitro, stimulates dissociation of TOP1 from DNA after cleavage and enhances its jumping between separate DNA helices. The SFPQ-NONO heteromer may be involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination and may stabilize paired DNA ends; in vitro, the complex strongly stimulates DNA end joining, binds directly to the DNA substrates and cooperates with the Ku70/G22P1-Ku80/XRCC5 (Ku) dimer to establish a functional preligation complex. SFPQ is involved in transcriptional regulation. Transcriptional repression is probably mediated by an interaction of SFPQ with SIN3A and subsequent recruitment of histone deacetylases (HDACs). The SFPQ-NONO/SF-1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. SFPQ isoform Long binds to the DNA binding domains (DBD) of nuclear hormone receptors, like RXRA and probably THRA, and acts as transcriptional corepressor in absence of hormone ligands. Binds the DNA sequence 5'-CTGAGTC-3' in the insulin-like growth factor response element (IGFRE) and inhibits IGF-I-stimulated transcriptional activity.
    Subcellular Location:
    Nucleus matrix Predominantly in nuclear matrix.
    Protein Attributes:
    Sequence length:
    707
    Sequence:
    50:
    MSRDRFRSRG | GGGGGFHRRG | GGGGRGGLHD | FRSPPPGMGL | NQNRGPMGPG | 
    100:
    PGQSGPKPPI | PPPPPHQQQQ | QPPPQQPPPQ | QPPPHQPPPH | PQPHQQQQPP | 
    150:
    PPPQDSSKPV | VAQGPGPAPG | VGSAPPASSS | APPATPPTSG | APPGSGPGPT | 
    200:
    PTPPPAVTSA | PPGAPPPTPP | SSGVPTTPPQ | AGGPPPPPAA | VPGPGPGPKQ | 
    250:
    GPGPGGPKGG | KMPGGPKPGG | GPGLSTPGGH | PKPPHRGGGE | PRGGRQHHPP | 
    300:
    YHQQHHQGPP | PGGPGGRSEE | KISDSEGFKA | NLSLLRRPGE | KTYTQRCRLF | 
    350:
    VGNLPADITE | DEFKRLFAKY | GEPGEVFINK | GKGFGFIKLE | SRALAEIAKA | 
    400:
    ELDDTPMRGR | QLRVRFATHA | AALSVRNLSP | YVSNELLEEA | FSQFGPIERA | 
    450:
    VVIVDDRGRS | TGKGIVEFAS | KPAARKAFER | CSEGVFLLTT | TPRPVIVEPL | 
    500:
    EQLDDEDGLP | EKLAQKNPMY | QKERETPPRF | AQHGTFEYEY | SQRWKSLDEM | 
    550:
    EKQQREQVEK | NMKDAKDKLE | SEMEDAYHEH | QANLLRQDLM | RRQEELRRME | 
    600:
    ELHNQEMQKR | KEMQLRQEEE | RRRREEEMMI | RQREMEEQMR | RQREESYSRM | 
    650:
    GYMDPRERDM | RMGGGGAMNM | GDPYGSGGQK | FPPLGGGGGI | GYEANPGVPP | 
    700:
    ATMSGSMMGS | DMRTERFGQG | GAGPVGGQGP | RGMGPGTPAG | YGRGREEYEG | 
    707:
    PNKKPRF
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    KEGG:
    SMR:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Splicing factor, proline- and glutamine-rich
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    E11562h
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    ELISA Kit for Human Splicing factor, proline- and glutamine-rich
    Cat.:
    E11562m
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    Packing:
    96T
    CLIA Kit for Human Splicing factor, proline- and glutamine-rich
    Cat.:
    U11562h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Splicing factor, proline- and glutamine-rich
    Cat.:
    U11562m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Splicing factor, proline- and glutamine-rich
    Cat.:
    P11562Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Splicing factor, proline- and glutamine-rich
    Cat.:
    P11562Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Splicing factor, proline- and glutamine-rich
    Monoclonal Antibody for Human Splicing factor, proline- and glutamine-rich
    Protein for Human Splicing factor, proline- and glutamine-rich
    Protein for Human Splicing factor, proline- and glutamine-rich

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and characterization of PSF, a novel pre-mRNA splicing factor."
      Patton J.G. , Porro E.B. , Galceran J. , Tempst P. , Nadal-Ginard B.
      Genes Dev.7:393-406(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;ALTERNATIVE SPLICING;FUNCTION
      tissue: Fetal brain.
    2. 2.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      Bienvenut W.V. , Lilla S. , von Kriegsheim A. , Lempens A. , Kolch W.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 33-44; 218-236; 246-267; 272-286; 299-315; 320-330; 350-358; 364-407; 414-425; 431-462; 480-493; 517-536; 549-559; 567-572; 575-581; 600-606; 612-630 AND 667-695;METHYLATION AT LYS-314; ARG-571; ARG-681 AND ARG-693;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Ovarian carcinoma.
    5. 5.
      "Purification and characterization of a DNA-binding heterodimer of 52 and 100 kDa from HeLa cells."
      Zhang W.-W. , Zhang L.-X. , Busch R.K. , Farres J. , Busch H.
      Biochem. J.290:267-272(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 48-68 AND 213-246;BLOCKAGE OF N-TERMINUS;DNA-BINDING;SUBUNIT
    6. 6.
      "The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p."
      Teigelkamp S. , Mundt C. , Achsel T. , Will C.L. , Luehrmann R.
      RNA3:1313-1326(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 292-311; 415-421 AND 503-510;IDENTIFICATION IN U5/4/6 SNRNP COMPLEXES
    7. 7.
      Lubec G. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 299-314 AND 480-493;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Fetal brain cortex.
    8. 8.
      "Cloning and characterization of a myoblast cell surface antigen defined by 24.1D5 monoclonal antibody."
      Gower H.J. , Moore S.E. , Dickson G. , Elsom V.L. , Nayak R. , Walsh F.S.
      Development105:723-731(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 312-707
      tissue: Fetal skeletal muscle.
    9. 9.
      "The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor."
      Lutz C.S. , Cooke C. , O'Connor J.P. , Kobayashi R. , Alwine J.C.
      RNA4:1493-1499(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 414-421 AND 427-448;SUBCELLULAR LOCATION;INTERACTION WITH SNRPA;IDENTIFICATION IN A SNRNP-FREE COMPLEX WITH SNRPA
    10. 10.
      "Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB."
      Meissner M. , Dechat T. , Gerner C. , Grimm R. , Foisner R. , Sauermann G.
      J. Cell. Biochem.76:559-566(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 600-606 AND 667-677;INTERACTION WITH PTBP1;SUBCELLULAR LOCATION
    11. 11.
      "A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction."
      Gozani O. , Patton J.G. , Reed R.
      EMBO J.13:3356-3367(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PRE-MRNA;IDENTIFICATION IN SPLICEOSOME COMPLEX
    12. 12.
      "Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma."
      Clark J. , Lu Y.-J. , Sidhar S.K. , Parker C. , Gill S. , Smedley D. , Hamoudi R. , Linehan W.M. , Shipley J. , Cooper C.S.
      Oncogene15:2233-2239(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH TFE3
    13. 13.
      "The RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interaction."
      Straub T. , Grue P. , Uhse A. , Lisby M. , Knudsen B.R. , Tange T.O. , Westergaard O. , Boege F.
      J. Biol. Chem.273:26261-26264(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TOP1;IDENTIFICATION IN A COMPLEX WITH NONO AND TOP1
    14. 14.
      "PSF/p54(nrb) stimulates 'jumping' of DNA topoisomerase I between separate DNA helices."
      Straub T. , Knudsen B.R. , Boege F.
      Biochemistry39:7552-7558(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DNA UNWINDING
    15. 15.
      "Polypyrimidine tract-binding protein-associated splicing factor is a negative regulator of transcriptional activity of the porcine p450scc insulin-like growth factor response element."
      Urban R.J. , Bodenburg Y. , Kurosky A. , Wood T.G. , Gasic S.
      Mol. Endocrinol.14:774-782(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN TRANSCRIPTION REGULATION;IDENTIFICATION BY MASS SPECTROMETRY
    16. 16.
      "Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasion."
      Akhmedov A.T. , Lopez B.S.
      Nucleic Acids Res.28:3022-3030(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN HOMOLOGOUS DNA PAIRING;PHOSPHORYLATION
    17. 17.
      "The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs."
      Zhang Z. , Carmichael G.G.
      Cell106:465-475(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NUCLEAR RETENTION OF A-TO-I EDITED RNAS;IDENTIFICATION IN A COMPLEX WITH NONO AND MATR3
    18. 18.
      "Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactions."
      Shav-Tal Y. , Cohen M. , Lapter S. , Dye B. , Patton J.G. , Vandekerckhove J. , Zipori D.
      Mol. Biol. Cell12:2328-2340(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SNRNP70;PHOSPHORYLATION
    19. 19.
      "PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors."
      Mathur M. , Tucker P.W. , Samuels H.H.
      Mol. Cell. Biol.21:2298-2311(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN TRANSCRIPTION REGULATION;INTERACTION WITH RXRA; THRA AND SIN3A
    20. 20.
      "Transcriptional activation of human CYP17 in H295R adrenocortical cells depends on complex formation among p54(nrb)/NonO, protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription."
      Sewer M.B. , Nguyen V.Q. , Huang C.J. , Tucker P.W. , Kagawa N. , Waterman M.R.
      Endocrinology143:1280-1290(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN TRANSCRIPTION REGULATION;INTERACTION WITH NR5A1 AND SIN3A;IDENTIFICATION IN A COMPLEX WITH NONO AND NR5A1
    21. 21.
      "PSF and p54nrb bind a conserved stem in U5 snRNA."
      Peng R. , Dye B.T. , Perez I. , Barnard D.C. , Thompson A.B. , Patton J.G.
      RNA8:1334-1347(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NONO AND U5 SNRNA;IDENTIFICATION IN IN U5/4/6 SNRNP SND SPLICEOSOME COMPLEXES
    22. 22.
      "Identification of the polypyrimidine tract binding protein-associated splicing factor.p54(nrb) complex as a candidate DNA double-strand break rejoining factor."
      Bladen C.L. , Udayakumar D. , Takeda Y. , Dynan W.S.
      J. Biol. Chem.280:5205-5210(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DNA REPAIR;IDENTIFICATION BY MASS SPECTROMETRY;DNA-BINDING;SUBUNIT
    23. 23.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-293
    24. 24.
      "The PSF.p54nrb complex is a novel Mnk substrate that binds the mRNA for tumor necrosis factor alpha."
      Buxade M. , Morrice N. , Krebs D.L. , Proud C.G.
      J. Biol. Chem.283:57-65(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-8 AND SER-283 BY MKNK2
    25. 25.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-687;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    26. 26.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-273 AND THR-687;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    27. 27.
      "Proteomic identification of a PSF/p54nrb heterodimer as RNF43 oncoprotein-interacting proteins."
      Miyamoto K. , Sakurai H. , Sugiura T.
      Proteomics8:2907-2910(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RNF43
    28. 28.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    29. 29.
      "BRK phosphorylates PSF promoting its cytoplasmic localization and cell cycle arrest."
      Lukong K.E. , Huot M.E. , Richard S.
      Cell. Signal.21:1415-1422(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;INTERACTION WITH PTK6;SUBCELLULAR LOCATION
    30. 30.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-379;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    31. 31.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-319; LYS-338; LYS-421 AND LYS-472;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    32. 32.
      "Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing."
      Heyd F. , Lynch K.W.
      Mol. Cell40:126-137(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION AT THR-687;INTERACTION WITH THRAP3;MUTAGENESIS OF THR-687
    33. 33.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-33 AND SER-626;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    34. 34.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    35. 35.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-33; SER-273 AND SER-283;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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