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Index > Protein center > Sfrp1(Gene name) > Rat
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  • Sfrp1 (Gene name),
  • Secreted frizzled-related protein 1 (Protein name ),  SFRP1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Sfrp1;
    Protein name:
    Secreted frizzled-related protein 1(sFRP-1);
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with WNT4. Interects with WNT1, WNT2, WNT8 and FRZD6.
    Function:
    Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi. Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
    Subcellular Location:
    Secreted Cell membrane or extracellular matrix-associated. Released by heparin-binding.
    Protein Attributes:
    Sequence length:
    158
    Sequence:
    50:
    VRDSCEPVMQ | FFGFYWPEML | KCDKFPEGDV | CIAMTPPNAT | EASKPQGTTV | 
    100:
    CPPCDNELKS | EAIIEHLCAS | EFALRMKIKE | VKKENGDKKI | VPKKKKPLKL | 
    150:
    GPIKKKELKR | LVLFLKNGAD | CPCHQLDNLS | HNFLIMGRKV | KSQYLLTAIH | 
    158:
    KWDKKNKE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat sFRP-1
    Cat.:
    E1165m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat sFRP-1
    Cat.:
    E1165h
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    96T
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    ELISA Kit for Rat sFRP-1
    Cat.:
    E1165b
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    Packing:
    96T
    ELISA Kit for Rat sFRP-1
    Cat.:
    E1165r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat sFRP-1
    Cat.:
    E1165c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat sFRP-1
    Cat.:
    U1165m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat sFRP-1
    Cat.:
    U1165h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Rat sFRP-1
    Cat.:
    U1165c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat sFRP-1
    Cat.:
    U1165r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat sFRP-1
    Cat.:
    U1165b
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat sFRP-1
    Polyclonal Antibody for Rat sFRP-1
    Cat.:
    P1165Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat sFRP-1
    Polyclonal Antibody for Rat sFRP-1
    Cat.:
    P1165Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat sFRP-1
    Cat.:
    P1165Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat sFRP-1
    Monoclonal Antibody for Rat sFRP-1
    Monoclonal Antibody for Rat sFRP-1
    Monoclonal Antibody for Rat sFRP-1
    Monoclonal Antibody for Rat sFRP-1
    Protein for Rat sFRP-1
    Protein for Rat sFRP-1
    Protein for Rat sFRP-1
    Protein for Rat sFRP-1
    Protein for Rat sFRP-1

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    References
    1. 1.
      "Secreted Frizzled-related proteins can regulate metanephric development."
      Yoshino K. , Rubin J.S. , Higinbotham K.G. , Uren A. , Anest V. , Plisov S.Y. , Perantoni A.O.
      Mech. Dev.102:45-55(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DEVELOPMENTAL STAGE
      strain: Fischer.
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