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Index > Protein center > CMA1(Gene name) > Human
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  • CMA1 (Gene name),
  • Chymase (Protein name ),  CMA1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CMA1(CYH;CYM);
    Protein name:
    Chymase;
    Alternative:
    Mast cell protease I;Alpha-chymase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
    Subcellular Location:
    Secreted Cytoplasmic granule Mast cell granules.
    Protein Attributes:
    Sequence length:
    247
    Sequence:
    50:
    MLLLPLPLLL | FLLCSRAEAG | EIIGGTECKP | HSRPYMAYLE | IVTSNGPSKF | 
    100:
    CGGFLIRRNF | VLTAAHCAGR | SITVTLGAHN | ITEEEDTWQK | LEVIKQFRHP | 
    150:
    KYNTSTLHHD | IMLLKLKEKA | SLTLAVGTLP | FPSQFNFVPP | GRMCRVAGWG | 
    200:
    RTGVLKPGSD | TLQEVKLRLM | DPQACSHFRD | FDHNLQLCVG | NPRKTKSAFK | 
    247:
    GDSGGPLLCA | GVAQGIVSYG | RSDAKPPAVF | TRISHYRPWI | NQILQAN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Chymase
    Cat.:
    E2059h
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    96T
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    ELISA Kit for Human Chymase
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    E2059m
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    96T
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    ELISA Kit for Human Chymase
    Cat.:
    E2059r
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    96T
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    ELISA Kit for Human Chymase
    Cat.:
    E2059d
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    Packing:
    96T
    ELISA Kit for Human Chymase
    MSDS:
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    CLIA Kit for Human Chymase
    Cat.:
    U2059d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Chymase
    Cat.:
    U2059r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Chymase
    Cat.:
    U2059m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human Chymase
    MSDS:
    Please sign in first.
    CLIA Kit for Human Chymase
    Cat.:
    U2059h
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    Please sign in first.
    MSDS:
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    Packing:
    96T
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    Polyclonal Antibody for Human Chymase
    Polyclonal Antibody for Human Chymase
    Cat.:
    P2059Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Chymase
    Cat.:
    P2059Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Chymase
    Cat.:
    P2059Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Chymase
    Monoclonal Antibody for Human Chymase
    Monoclonal Antibody for Human Chymase
    Monoclonal Antibody for Human Chymase
    Monoclonal Antibody for Human Chymase
    Monoclonal Antibody for Human Chymase
    Protein for Human Chymase
    Protein for Human Chymase
    Protein for Human Chymase
    Protein for Human Chymase
    Protein for Human Chymase

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    Linearity
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    References
    1. 1.
      "Structure, chromosomal assignment, and deduced amino acid sequence of a human gene for mast cell chymase."
      Caughey G.H. , Zerweck E.H. , Vanderslice P.
      J. Biol. Chem.266:12956-12963(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
      tissue: Heart.
    3. 3.
      "Determination of the primary structures of human skin chymase and cathepsin G from cutaneous mast cells of urticaria pigmentosa lesions."
      Schechter N.M. , Wang Z.M. , Blacher R.W. , Lessin S.R. , Lazarus G.S. , Rubin H.
      J. Immunol.152:4062-4069(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 22-56; 123-132; 136-148; 167-194 AND 197-247;TISSUE SPECIFICITY
      tissue: Skin.
    4. 4.
      "Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
      Goshima N. , Kawamura Y. , Fukumoto A. , Miura A. , Honma R. , Satoh R. , Wakamatsu A. , Yamamoto J. , Kimura K. , Nishikawa T. , Andoh T. , Iida Y. , Ishikawa K. , Ito E. , Kagawa N. , Kaminaga C. , Kanehori K. , Kawakami B. , more...
      Nat. Methods5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      "The DNA sequence and analysis of human chromosome 14."
      Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
      Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT ARG-66
    8. 8.
      "Purification and molecular cloning of chymase from human tonsils."
      Sukenaga Y. , Kido H. , Neki A. , Enomoto M. , Ishida K. , Takagi K. , Katunuma N.
      FEBS Lett.323:119-122(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 22-247 (ISOFORM 1)
    9. 9.
      "Angiotensin II-forming heart chymase is a mast-cell-specific enzyme."
      Jenne D.E. , Tschopp J.
      Biochem. J.276:567-568(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 26-60
      tissue: Placenta.
    10. 10.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-80 AND ASN-103
      tissue: Liver.
    11. 11.
      "Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A."
      McGrath M.E. , Mirzadegan T. , Schmidt B.F.
      Biochemistry36:14318-14324(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS)
    12. 12.
      "The 2.2-A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity."
      Pereira P.J.P. , Wang Z.-M. , Rubin H. , Huber R. , Bode W. , Schechter N.M. , Strobl S.
      J. Mol. Biol.286:163-173(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
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