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Index > Protein center > C8b(Gene name) > Rat
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  • C8b (Gene name),
  • Complement component C8 beta chain (Protein name ),  CO8B_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    C8b;
    Protein name:
    Complement component C8 beta chain;
    Alternative:
    Complement component 8 subunit beta;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Heterotrimer of 3 chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded. Component of the membrane attack complex (MAC). MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9.
    Function:
    Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    589
    Sequence:
    50:
    MKTGAQVWRA | LAKSCLLCAA | LGCLHLPGAR | GEKPDFFETN | AVNGSLVRSR | 
    100:
    PVRSVDVTPA | PTDCQLSTWS | SWTACDPCQK | KRYRHTYLLR | PSQFYGELCD | 
    150:
    FSDKEVEDCV | TNRACRSQVR | CEGFVCAQTG | RCVNRRLLCN | GDNDCGDQSD | 
    200:
    EANCRRIYKK | CSQDMEQYWA | IGNLASGINL | FTNTFEGPVL | DHRYYAGACS | 
    250:
    PHYILNTNFR | KPYNVESYTP | QTQGKYEFAL | TEYESYFDFE | HNVTEKATSK | 
    300:
    SSFKFGFKLD | GLVEFGVRKE | SNEGRHYISR | TKRFSHTKSK | FLHARSVLEV | 
    350:
    AHYKLKSRQL | MLHYEFLQRV | KSLPLEYSYG | EYRDLLRDFG | THFITEAVLG | 
    400:
    GIYEYTLIMN | KDAMERGDYT | LDHVSACAGG | GFQIGGNVYK | VYLKLGVSEK | 
    450:
    KCSDILNEIK | DRNKRRTMVE | DLVVLVRGGT | SEYITSLAYK | DLPTAELMKE | 
    500:
    WGDAVQYNPA | IIKLKAEPLY | ELVTATDFAY | SSTVKQNMKK | ALEEFQMEVS | 
    550:
    SCRCAPCRNN | GVPILKESRC | ECICPAGFQG | VACEVTNRKD | IPIDGKWSCW | 
    589:
    SDWSPCSGGR | KTRQRQCNNP | APQRGGSPCS | GPASETLDC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Complement component C8 beta chain
    Cat.:
    E9155m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Complement component C8 beta chain
    Cat.:
    E9155r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Complement component C8 beta chain
    Cat.:
    E9155h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Complement component C8 beta chain
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Complement component C8 beta chain
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Complement component C8 beta chain
    Cat.:
    U9155r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Complement component C8 beta chain
    Cat.:
    U9155m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Complement component C8 beta chain
    Cat.:
    U9155h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Complement component C8 beta chain
    Cat.:
    P9155Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Complement component C8 beta chain
    Polyclonal Antibody for Rat Complement component C8 beta chain
    Cat.:
    P9155Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Complement component C8 beta chain
    Monoclonal Antibody for Rat Complement component C8 beta chain
    Monoclonal Antibody for Rat Complement component C8 beta chain
    Monoclonal Antibody for Rat Complement component C8 beta chain
    Monoclonal Antibody for Rat Complement component C8 beta chain
    Protein for Rat Complement component C8 beta chain
    Protein for Rat Complement component C8 beta chain
    Protein for Rat Complement component C8 beta chain
    Protein for Rat Complement component C8 beta chain

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    Recovery
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    Linearity
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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-259 AND 160-589
      tissue: Liver.
    3. 3.
      "Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus."
      Kershaw E.E. , Chua S.C. , Williams J.A. , Murphy E.M. , Leibel R.L.
      Genomics27:149-154(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 450-589
      strain: Brown Norway/Crl.
      tissue: Liver.
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