Protein name:
Complement component C8 beta chain ;
Alternative:
Complement component 8 subunit beta ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Heterotrimer of 3 chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded. Component of the membrane attack complex (MAC). MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9.
Function:
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Subcellular Location:
Secreted
Protein Attributes:
50:
MKTGAQVWRA | LAKSCLLCAA | LGCLHLPGAR | GEKPDFFETN | AVNGSLVRSR |
100:
PVRSVDVTPA | PTDCQLSTWS | SWTACDPCQK | KRYRHTYLLR | PSQFYGELCD |
150:
FSDKEVEDCV | TNRACRSQVR | CEGFVCAQTG | RCVNRRLLCN | GDNDCGDQSD |
200:
EANCRRIYKK | CSQDMEQYWA | IGNLASGINL | FTNTFEGPVL | DHRYYAGACS |
250:
PHYILNTNFR | KPYNVESYTP | QTQGKYEFAL | TEYESYFDFE | HNVTEKATSK |
300:
SSFKFGFKLD | GLVEFGVRKE | SNEGRHYISR | TKRFSHTKSK | FLHARSVLEV |
350:
AHYKLKSRQL | MLHYEFLQRV | KSLPLEYSYG | EYRDLLRDFG | THFITEAVLG |
400:
GIYEYTLIMN | KDAMERGDYT | LDHVSACAGG | GFQIGGNVYK | VYLKLGVSEK |
450:
KCSDILNEIK | DRNKRRTMVE | DLVVLVRGGT | SEYITSLAYK | DLPTAELMKE |
500:
WGDAVQYNPA | IIKLKAEPLY | ELVTATDFAY | SSTVKQNMKK | ALEEFQMEVS |
550:
SCRCAPCRNN | GVPILKESRC | ECICPAGFQG | VACEVTNRKD | IPIDGKWSCW |
589:
SDWSPCSGGR | KTRQRQCNNP | APQRGGSPCS | GPASETLDC
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Rabbit
ELISA Kit for Rat Complement component C8 beta chain
ELISA Kit for Rat Complement component C8 beta chain
ELISA Kit for Rat Complement component C8 beta chain
ELISA Kit for Rat Complement component C8 beta chain
CLIA Kit for Rat Complement component C8 beta chain
CLIA Kit for Rat Complement component C8 beta chain
CLIA Kit for Rat Complement component C8 beta chain
CLIA Kit for Rat Complement component C8 beta chain
Polyclonal Antibody for Rat Complement component C8 beta chain
Polyclonal Antibody for Rat Complement component C8 beta chain
Polyclonal Antibody for Rat Complement component C8 beta chain
Polyclonal Antibody for Rat Complement component C8 beta chain
Monoclonal Antibody for Rat Complement component C8 beta chain
Monoclonal Antibody for Rat Complement component C8 beta chain
Monoclonal Antibody for Rat Complement component C8 beta chain
Monoclonal Antibody for Rat Complement component C8 beta chain
Protein for Rat Complement component C8 beta chain
Protein for Rat Complement component C8 beta chain
Protein for Rat Complement component C8 beta chain
Protein for Rat Complement component C8 beta chain
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Gibbs R.A.
,
Weinstock G.M.
,
Metzker M.L.
,
Muzny D.M.
,
Sodergren E.J.
,
Scherer S.
,
Scott G.
,
Steffen D.
,
Worley K.C.
,
Burch P.E.
,
Okwuonu G.
,
Hines S.
,
Lewis L.
,
Deramo C.
,
Delgado O.
,
Dugan-Rocha S.
,
Miner G.
,
Morgan M.
,
Hawes A.
,
Gill R.
,
Holt R.A.
,
Adams M.D.
,
Amanatides P.G.
,
Baden-Tillson H.
,
Barnstead M.
,
Chin S.
,
Evans C.A.
,
Ferriera S.
,
Fosler C.
,
Glodek A.
,
Gu Z.
,
Jennings D.
,
Kraft C.L.
,
Nguyen T.
,
Pfannkoch C.M.
,
Sitter C.
,
Sutton G.G.
,
Venter J.C.
,
Woodage T.
,
Smith D.
,
Lee H.-M.
,
Gustafson E.
,
Cahill P.
,
Kana A.
,
Doucette-Stamm L.
,
Weinstock K.
,
Fechtel K.
,
Weiss R.B.
,
Dunn D.M.
,
Green E.D.
,
Blakesley R.W.
,
Bouffard G.G.
,
De Jong P.J.
,
Osoegawa K.
,
Zhu B.
,
Marra M.
,
Schein J.
,
Bosdet I.
,
Fjell C.
,
Jones S.
,
Krzywinski M.
,
Mathewson C.
,
Siddiqui A.
,
Wye N.
,
McPherson J.
,
Zhao S.
,
Fraser C.M.
,
Shetty J.
,
Shatsman S.
,
Geer K.
,
Chen Y.
,
Abramzon S.
,
Nierman W.C.
,
Havlak P.H.
,
Chen R.
,
Durbin K.J.
,
Egan A.
,
Ren Y.
,
Song X.-Z.
,
Li B.
,
Liu Y.
,
Qin X.
,
Cawley S.
,
Cooney A.J.
,
D'Souza L.M.
,
Martin K.
,
Wu J.Q.
,
Gonzalez-Garay M.L.
,
Jackson A.R.
,
Kalafus K.J.
,
McLeod M.P.
,
Milosavljevic A.
,
Virk D.
,
Volkov A.
,
Wheeler D.A.
,
Zhang Z.
,
Bailey J.A.
,
Eichler E.E.
,
Tuzun E.
,
Birney E.
,
Mongin E.
,
Ureta-Vidal A.
,
Woodwark C.
,
Zdobnov E.
,
Bork P.
,
Suyama M.
,
Torrents D.
,
Alexandersson M.
,
Trask B.J.
,
Young J.M.
,
Huang H.
,
Wang H.
,
Xing H.
,
Daniels S.
,
Gietzen D.
,
Schmidt J.
,
Stevens K.
,
Vitt U.
,
Wingrove J.
,
Camara F.
,
Mar Alba M.
,
Abril J.F.
,
Guigo R.
,
Smit A.
,
Dubchak I.
,
Rubin E.M.
,
Couronne O.
,
Poliakov A.
,
Huebner N.
,
Ganten D.
,
Goesele C.
,
Hummel O.
,
Kreitler T.
,
Lee Y.-A.
,
Monti J.
,
Schulz H.
,
Zimdahl H.
,
Himmelbauer H.
,
Lehrach H.
,
Jacob H.J.
,
Bromberg S.
,
Gullings-Handley J.
,
Jensen-Seaman M.I.
,
Kwitek A.E.
,
Lazar J.
,
Pasko D.
,
Tonellato P.J.
,
Twigger S.
,
Ponting C.P.
,
Duarte J.M.
,
Rice S.
,
Goodstadt L.
,
Beatson S.A.
,
Emes R.D.
,
Winter E.E.
,
Webber C.
,
Brandt P.
,
Nyakatura G.
,
Adetobi M.
,
Chiaromonte F.
,
Elnitski L.
,
Eswara P.
,
Hardison R.C.
,
Hou M.
,
Kolbe D.
,
Makova K.
,
Miller W.
,
Nekrutenko A.
,
Riemer C.
,
Schwartz S.
,
Taylor J.
,
Yang S.
,
Zhang Y.
,
Lindpaintner K.
,
Andrews T.D.
,
Caccamo M.
,
Clamp M.
,
Clarke L.
,
Curwen V.
,
Durbin R.M.
,
Eyras E.
,
Searle S.M.
,
Cooper G.M.
,
Batzoglou S.
,
Brudno M.
,
Sidow A.
,
Stone E.A.
,
Payseur B.A.
,
Bourque G.
,
Lopez-Otin C.
,
Puente X.S.
,
Chakrabarti K.
,
Chatterji S.
,
Dewey C.
,
Pachter L.
,
Bray N.
,
Yap V.B.
,
Caspi A.
,
Tesler G.
,
Pevzner P.A.
,
Haussler D.
,
Roskin K.M.
,
Baertsch R.
,
Clawson H.
,
Furey T.S.
,
Hinrichs A.S.
,
Karolchik D.
,
Kent W.J.
,
Rosenbloom K.R.
,
Trumbower H.
,
Weirauch M.
,
Cooper D.N.
,
Stenson P.D.
,
Ma B.
,
Brent M.
,
Arumugam M.
,
Shteynberg D.
,
Copley R.R.
,
Taylor M.S.
,
Riethman H.
,
Mudunuri U.
,
Peterson J.
,
Guyer M.
,
Felsenfeld A.
,
Old S.
,
Mockrin S.
,
Collins F.S.
more...
Nature428:493-521(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Brown Norway .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-259 AND 160-589
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 450-589
strain :
Brown Norway/Crl .
tissue :
Liver .