Gene name:
Phf1(Plc1;Tctex-3;Tctex3);
Protein name:
PHD finger protein 1(Protein PHF1);
Alternative:
T-complex testis-expressed 3;Polycomb-like protein 1(mPCl1);
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with the PRC2/EED-EZH2 complex (By similarity). Interacts with CHMP1.
Function:
Transcriptional repressor. May promote methylation of histone H3 on 'Lys-27' by the PRC2 complex.
Subcellular Location:
Nucleus
Cytoplasm
cytoskeleton
centrosome
Localizes specifically to the promoters of numerous target genes. Co-localizes with NEK6 in the centrosome.
Protein Attributes:
50:
MAQLPRLSRL | GAPSLWDPAS | PAPTSGPRPR | LWEGQDVLAR | WTDGLLYLGT |
100:
IKKVDSAREV | CLVQFEDDSQ | FLVLWKDISP | AALPGEELLC | CVCRSETVVP |
150:
GNRLVSCEKC | RHAYHQDCHV | PRAPAPGEGE | GASWVCRQCV | FAIATKRGGA |
200:
LKKGPYARAM | LGMKLSLPYG | LKGLDWDAGH | LSNRQQSYCY | CGGPGEWNLK |
250:
MLQCRSCLQW | FHEACTQCLS | KPLLYGDRFY | EFECCVCRGG | PEKVRRLQLR |
300:
WVDVAHLVLY | HLSVCCKKKY | FDFDREILPF | TSENWDSLLL | GELSDTPKGE |
350:
RSSQLLSALN | SHKDRFISGR | EIKKRKCLFG | LHARTPPPVE | LLTGDGAPTS |
400:
FPSGQGPGGG | VSRPLGKRWR | SEPEPLRRRQ | KGKVEELGPP | TAAHSRHGSR |
450:
EQRALQASVS | PPPPSPNQSY | EGSSGYNFRP | TDARCLPSSP | IRMFASFHPS |
500:
ASTAGTSGDS | EPPDRSPLGL | HIGFPTDTPK | SSPHSVTASS | SSVPALTPGF |
550:
SRHSPPSPLC | RSLSPGTGGG | VRGGVSYLSR | GDPVRVLARR | VRPDGSVQYL |

Vaild Sequence:
Related Databases
Uniprot:
FOR
ELISA Kit for Mouse Protein PHF1
ELISA Kit for Mouse Protein PHF1
CLIA Kit for Mouse Protein PHF1
CLIA Kit for Mouse Protein PHF1
Polyclonal Antibody for Mouse Protein PHF1
Polyclonal Antibody for Mouse Protein PHF1
Monoclonal Antibody for Mouse Protein PHF1
Monoclonal Antibody for Mouse Protein PHF1
Protein for Mouse Protein PHF1
Protein for Mouse Protein PHF1
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
-
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue:
Testis.
-
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain:
NIH Swiss.
-
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: INTERACTION WITH CHMP1
-
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: FUNCTION;SUBCELLULAR LOCATION
-
5.
"Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity."
Ballare C.
,
Lange M.
,
Lapinaite A.
,
Martin G.M.
,
Morey L.
,
Pascual G.
,
Liefke R.
,
Simon B.
,
Shi Y.
,
Gozani O.
,
Carlomagno T.
,
Benitah S.A.
,
Di Croce L.
Nat. Struct. Mol. Biol.19:1257-1265(2012)
[
PubMed]
[
Europe PMC]
[
Abstract]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: H3K36ME3-BINDING