Gene name:
EIF2S1 (EIF2A) ;
Protein name:
Eukaryotic translation initiation factor 2 subunit 1 ;
Alternative:
Eukaryotic translation initiation factor 2 subunit alpha (eIF-2-alpha;eIF-2A;eIF-2alpha) ;
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
Heterotrimer composed of an alpha, a beta and a gamma chain. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. Interacts with ABCF1. Associates with ribosomes.
Function:
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Subcellular Location:
Cytoplasmic granule
The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Co-localizes with NANOS3 in the stress granules.
Protein Attributes:
50:
PGLSCRFYQH | KFPEVEDVVM | VNVRSIAEMG | AYVSLLEYNN | IEGRILLSEL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Rabbit
Mouse
Pig
Chicken
Rat
ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
ELISA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
CLIA Kit for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Polyclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Monoclonal Antibody for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 1
Protein for Rabbit Eukaryotic translation initiation factor 2 subunit 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE;PHOSPHORYLATION AT SER-48
tissue :
Reticulocyte .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 1-23
tissue :
Reticulocyte .