Protein name:
Complement component C8 beta chain ;
Alternative:
Complement component 8 subunit beta ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Heterotrimer of 3 chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded. Component of the membrane attack complex (MAC). MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9.
Function:
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
Subcellular Location:
Secreted
Protein Attributes:
50:
MKIGAQVWRA | LAKSCLLCAT | LGCLHFPGSR | GGKPDFFETK | AVNGSLVKSR |
100:
PVRSVAEAPA | PIDCELSTWS | SWTACDPCQK | KRYRHTYLLR | PSQFYGELCD |
150:
LSDKEVEDCV | TNQPCRSQVR | CEGFVCAQTG | RCVNRRLLCN | GDNDCGDQSD |
200:
EANCRRIYKN | CQREMEQYWA | IDRLASGINL | FTNTFEGPVL | DHRYYAGGCS |
250:
PHYILDTNFR | KPYNVESYTP | QTKCEYEFTL | TEYESYSDFE | RLVIEKKTHM |
300:
FNFTSGFKVD | GVMDLGIKVE | SNEGKNYVTR | TKRFAHTQSK | FLHARSVLEV |
350:
AHYKLKSRSL | MLHYEFLQRV | KSLPLEYSYG | EYRDLLRDFG | THFITEAVLG |
400:
GIYEYTLIMN | KDAMEQGDYT | LSHVTACAGG | SFGIGGMVYK | VYVKVGVSAK |
450:
KCSDIMKEIN | ERNKRSTMVE | DLVVLVRGGT | SEDITALAYK | ELPTPELMEA |
500:
WGDAVKYNPA | IIKIKAEPLY | ELVTATDFAY | SSTVKQNLKK | ALEEFQSEVS |
550:
SCRCAPCRGN | GVPVLKGSRC | ECICPGGFQG | TACEVTYRKD | IPIDGKWSCW |
589:
SDWSACSGGH | KTRHRQCNNP | APHKGGSPCS | GPASETLNC
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Rabbit
ELISA Kit for Mouse Complement component C8 beta chain
ELISA Kit for Mouse Complement component C8 beta chain
ELISA Kit for Mouse Complement component C8 beta chain
ELISA Kit for Mouse Complement component C8 beta chain
CLIA Kit for Mouse Complement component C8 beta chain
CLIA Kit for Mouse Complement component C8 beta chain
CLIA Kit for Mouse Complement component C8 beta chain
CLIA Kit for Mouse Complement component C8 beta chain
Polyclonal Antibody for Mouse Complement component C8 beta chain
Polyclonal Antibody for Mouse Complement component C8 beta chain
Polyclonal Antibody for Mouse Complement component C8 beta chain
Polyclonal Antibody for Mouse Complement component C8 beta chain
Monoclonal Antibody for Mouse Complement component C8 beta chain
Monoclonal Antibody for Mouse Complement component C8 beta chain
Monoclonal Antibody for Mouse Complement component C8 beta chain
Monoclonal Antibody for Mouse Complement component C8 beta chain
Protein for Mouse Complement component C8 beta chain
Protein for Mouse Complement component C8 beta chain
Protein for Mouse Complement component C8 beta chain
Protein for Mouse Complement component C8 beta chain
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
strain :
DBA/2J .
strain :
Mae/Stm .
strain :
MSM/Ms .
tissue :
Liver .
2.
"The transcriptional landscape of the mammalian genome."
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[
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6J .
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
FVB/N .
tissue :
Liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-43 AND ASN-252
strain :
C57BL/6 .
tissue :
Plasma .