ETF1 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comETF1 Polyclonal Antibody for Human(Homo sapiens)

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Index > Protein center > ETF1(Gene name) > Human

ETF1 (Gene name),

Eukaryotic peptide chain release factor subunit 1 (Protein name ), ERF1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ETF1(ERF1;RF1;SUP45L1);

Protein name:

Eukaryotic peptide chain release factor subunit 1(Eukaryotic release factor 1;eRF1);

Alternative:

TB3-1;Protein Cl1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer of two subunits, one of which binds GTP. Component of the transient SURF (SMG1-UPF1-eRF1-eRF3) complex.

Function:

Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

437

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

437:

QFVKGFGGIG | GILRYRVDFQ | GMEYQGGDDE | FFDLDDY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:2107

STRING:

9606.ENSP00000353741

SMR:

P62495

String:

P62495

UniGene:

Hs.483494

MIM:

600285

Pfam:

PF03463

Uniprot:

P62495

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ELISA Kit for Human Eukaryotic release factor 1

Cat.:

E11482r

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96T

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ELISA Kit for Human Eukaryotic release factor 1

Cat.:

E11482h

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96T

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ELISA Kit for Human Eukaryotic release factor 1

Cat.:

E11482m

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96T

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ELISA Kit for Human Eukaryotic release factor 1

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ELISA Kit for Human Eukaryotic release factor 1

Cat.:

E11482b

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Packing:

96T

CLIA Kit for Human Eukaryotic release factor 1

Cat.:

U11482b

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MSDS:

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Packing:

96T

CLIA Kit for Human Eukaryotic release factor 1

Cat.:

U11482r

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MSDS:

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Packing:

96T

CLIA Kit for Human Eukaryotic release factor 1

MSDS:

Please sign in first.

CLIA Kit for Human Eukaryotic release factor 1

Cat.:

U11482m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Eukaryotic release factor 1

Cat.:

U11482h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Eukaryotic release factor 1

Cat.:

P11482Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Eukaryotic release factor 1

Cat.:

P11482Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Eukaryotic release factor 1

Cat.:

P11482Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Eukaryotic release factor 1

Monoclonal Antibody for Human Eukaryotic release factor 1

Protein for Human Eukaryotic release factor 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Identification of a human cDNA with high homology to yeast omnipotent suppressor 45."
Grenett H.E. , Fuller G.M. , Bounelis P.
Gene110:239-243(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor."
Frolova L. , Le Goff X. , Rasmussen H.H. , Cheprergin S. , Drugeon G. , Haenni A.-L. , Celis J.E. , Philippe M. , Justesen J. , Kisselev L.
Nature372:701-703(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION;FUNCTION
3.

"The catalytic subunit of protein phosphatase 2A associates with the translation termination factor eRF1."
Andjelkovic N. , Zolnierowicz S. , van Hoof C. , Goris J. , Hemmings B.A.
EMBO J.15:7156-7167(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain.
4.

"Human release factor eRF1: structural organisation of the unique functional gene on chromosome 5 and of the three processed pseudogenes."
Guenet L. , Toutain B. , Guilleret I. , Chauvel B. , Deaven L.L. , Longmire J.L. , Le Gall L.Y. , David V. , Le Treut A.
FEBS Lett.454:131-136(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
6.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Thalamus.
7.

"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J. , Martin J. , Terry A. , Couronne O. , Grimwood J. , Lowry S. , Gordon L.A. , Scott D. , Xie G. , Huang W. , Hellsten U. , Tran-Gyamfi M. , She X. , Prabhakar S. , Aerts A. , Altherr M. , Bajorek E. , Black S. , more...
Nature431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Lymph.
tissue: Testis.
10.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-10;ACETYLATION AT ALA-2
tissue: Platelet.
11.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.

"SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay."
Yamashita A. , Izumi N. , Kashima I. , Ohnishi T. , Saari B. , Katsuhata Y. , Muramatsu R. , Morita T. , Iwamatsu A. , Hachiya T. , Kurata R. , Hirano H. , Anderson P. , Ohno S.
Genes Dev.23:1091-1105(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE SURF COMPLEX
13.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
15.

"The crystal structure of human eukaryotic release factor eRF1 --mechanism of stop codon recognition and peptidyl-tRNA hydrolysis."
Song H. , Mugnier P. , Das A.K. , Webb H.M. , Evans D.R. , Tuite M.F. , Hemmings B.A. , Barford D.
Cell100:311-321(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS)
16.

"Eukaryotic class 1 translation termination factor eRF1 -- the NMR structure and dynamics of the middle domain involved in triggering ribosome-dependent peptidyl-tRNA hydrolysis."
Ivanova E.V. , Kolosov P.M. , Birdsall B. , Kelly G. , Pastore A. , Kisselev L.L. , Polshakov V.I.
FEBS J.274:4223-4237(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 140-277

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