Protein name:
Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1;eRF1) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Heterodimer of two subunits, one of which binds GTP. Component of the transient SURF (SMG1-UPF1-eRF1-eRF3) complex (By similarity). Interacts with Moloney murine leukemia virus (MoLV) reverse transcriptase/Ribonuclease H p80 (via RT and RNase domains); this interaction is essential for translational readthrough of amber codon between viral gag and pol genes. Interacts with MoLV Gag-Pol precursor.
Function:
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA (By similarity). Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MADDPSAADR | NVEIWKIKKL | IKSLEAARGN | GTSMISLIIP | PKDQISRVAK |
100:
MLADEFGTAS | NIKSRVNRLS | VLGAITSVQQ | RLKLYNKVPP | NGLVVYCGTI |
150:
VTEEGKEKKV | NIDFEPFKPI | NTSLYLCDNK | FHTEALTALL | SDDSKFGFIV |
200:
IDGSGALFGT | LQGNTREVLH | KFTVDLPKKH | GRGGQSALRF | ARLRMEKRHN |
250:
YVRKVAETAV | QLFISGDKVN | VAGLVLAGSA | DFKTELSQSD | MFDQRLQSKV |
300:
LKLVDISYGG | ENGFNQAIEL | STEVLSNVKF | IQEKKLIGRY | FDEISQDTGK |
350:
YCFGVEDTLK | ALEMGAVEIL | IVYENLDIMR | YVLHCQGTEE | EKILYLTPEQ |
400:
EKDKSHFTDK | ETGQEHELIE | SMPLLEWFAN | NYKKFGATLE | IVTDKSQEGS |
437:
QFVKGFGGIG | GILRYRVDFQ | GMEYQGGDDE | FFDLDDY
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
Rabbit
Bovine
ELISA Kit for Mouse Eukaryotic release factor 1
ELISA Kit for Mouse Eukaryotic release factor 1
ELISA Kit for Mouse Eukaryotic release factor 1
ELISA Kit for Mouse Eukaryotic release factor 1
ELISA Kit for Mouse Eukaryotic release factor 1
CLIA Kit for Mouse Eukaryotic release factor 1
CLIA Kit for Mouse Eukaryotic release factor 1
CLIA Kit for Mouse Eukaryotic release factor 1
CLIA Kit for Mouse Eukaryotic release factor 1
CLIA Kit for Mouse Eukaryotic release factor 1
Polyclonal Antibody for Mouse Eukaryotic release factor 1
Polyclonal Antibody for Mouse Eukaryotic release factor 1
Polyclonal Antibody for Mouse Eukaryotic release factor 1
Polyclonal Antibody for Mouse Eukaryotic release factor 1
Polyclonal Antibody for Mouse Eukaryotic release factor 1
Monoclonal Antibody for Mouse Eukaryotic release factor 1
Monoclonal Antibody for Mouse Eukaryotic release factor 1
Monoclonal Antibody for Mouse Eukaryotic release factor 1
Monoclonal Antibody for Mouse Eukaryotic release factor 1
Monoclonal Antibody for Mouse Eukaryotic release factor 1
Protein for Mouse Eukaryotic release factor 1
Protein for Mouse Eukaryotic release factor 1
Protein for Mouse Eukaryotic release factor 1
Protein for Mouse Eukaryotic release factor 1
Protein for Mouse Eukaryotic release factor 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Spinal cord .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE/RIBONUCLEASE H P80 AND GAG-POL POLYPROTEIN