Protein name:
Filamin-B (FLN-B) ;
Alternative:
Actin-binding-like protein ;ABP-280-like protein ;Beta-filamin ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer. Interacts with FLNA, FLNC, INPPL1, ITGB1A, ITGB1D, ITGB3, ITGB6, MYOT, MYOZ1, PSEN1 and PSEN2.
Function:
Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton.
Subcellular Location:
Cytoplasm
cell cortex
Cytoplasm
myofibril
sarcomere
Z line
Cytoplasm
cytoskeleton
May localize also at actin stress fibers and within the Z-lines.
Protein Attributes:
50:
MPVTEKDLAE | DAPWKKIQQN | TFTRWCNEHL | KCVNKRIGNL | QTDLSDGLRL |
100:
IALLEVLSQK | RMHHKYHQRP | TFRQMKLENV | SVALEFLDHE | SIKLVSIDSK |
150:
AIVDGNLKLI | LGLVWTLILH | YSISMPVWED | EGDDDAKKQT | PKQRLLGWIQ |
200:
NKIPYLPITN | FNQNWQDGKA | LGALVDSCAP | GLCPDWESWD | PRKPVDNARE |
250:
AMQQADDWLG | VPQVITPEEI | IHPDVDEHSV | MTYLSQFPKA | KLKPGAPLKP |
300:
KLNPKKARAY | GRGIEPTGNM | VKQPAKFTVD | TISAGQGDVM | VFVEDPEGNK |
350:
EEARVTPDSD | KNKTYSVEYL | PKVTGLHKVI | VLFAGQHISK | SPFEVNVDKA |
400:
QGDASKVTAK | GPGLETTGNI | ANKPTYFDIY | TAGAGVGDIG | IEVEDPQGKN |
450:
SVELLVEDRG | NQVYRCVYKP | VQPGPHVVKV | SFAGDAIPKS | PFGVQIGEAC |
500:
NPNACRASGR | GLQPKGVRIR | ETADFKVDTK | AAGSGELGVT | VKGPKGLEEL |
550:
VKQKGFLDGV | YSFEYYPSTP | GKYSVAVTWG | GHHIPKSPFE | VQVGPEAGMQ |
600:
KVRAWGPGLH | GGIVGRSADF | VVESIGSEVG | TLGFAIEGPS | QAKIEYDDQN |
650:
DGSCDVKYWP | KEPGEYAVHI | MCDDEDIKDS | PYMAFIHPAT | GDYNPDLVQA |
700:
YGPGLEKSGC | TINNPAEFIV | DPKDAGSAPL | KILAQDGEGQ | PIDIQMKSRM |
750:
DGTYACSYTP | LKAIKHTIAV | VWGGVNIPHS | PYRVNIGQGS | HPQKVKVFGP |
800:
GVERSGLKAN | EPTHFTVDCT | EAGEGDVSVG | IKCDARVLSD | DEEDVDFDII |
850:
HNANDTFTVK | YVPPAPGRYT | IKVLFASQEI | PASPFRVKVD | PSHDASKVKA |
900:
EGPGLSKAGV | ENGKPTHFTV | HTKGAGKAPL | NVQFSSPLPG | EAVKDLDIID |
950:
NYDYSHTVKY | TPTQQGNMQV | LVTYGGDPIP | KSPFTVGVAA | PLDLSKIKIN |
1000:
GLENRVEVGK | DQEFAIDTNG | AGGQGKLDVT | ILSPSRKVVP | CLVAPVAGRE |
1050:
CSTAKFIPRE | EGLFAVDVTY | DGHPVPGSPY | TVEASLPPDP | TKVKAHGPGL |
1100:
EGGLVGKPAE | FTIDTKGAGT | GGLGLTVEGP | CEAKIECSDN | GDGTCSVSYL |
1150:
PTKPGEYFVN | ILFEEVHIPG | SPFKADIEMP | FDPSKVVASG | PGLEHGKVGE |
1200:
PGILCVDCSE | AGPGTLGLEA | VSDSGAKAEV | SIQNNKDGTY | AVTYVPLTAG |
1250:
MYTLTMKYGG | ELVPHFPAWV | KVEPAIDTSG | IKAFGPGIEG | KDVFREATTD |
1300:
FTVDSRPLTQ | VGGDHIKAQI | TNPSGASTEC | FVKDNADGTY | QVEYTPFEKG |
1350:
FHVVEVTYDD | VPIPNSPFKV | AVTEGCQPSR | VHAQGPGLKE | AFTNKSNVFT |
1400:
VVTRGAGIGG | LGITVEGPSE | SKINCRDNKD | GSCSAEYIPF | APGDYDVNIT |
1450:
YGGVHIPGSP | FRVPSKDVVD | PSKVKIAGPG | LSSCVRACIP | QSFTVDSSKA |
1500:
GLAPLEVRVL | GPRGLVEPVN | VVDNGDGTHT | VTYTPSQEGP | YIVSVKYADE |
1550:
EIPRSPFKVK | VLPTYDASKV | TASGPGLSAY | GVPASLPVEF | AIDARDAGEG |
1600:
LLAVQITDQE | GKPQRATVHD | NKDGTYAVTY | IPDKTGRYMI | GVTYGGDNIP |
1650:
LSPYRIRATQ | TGDASKCLAT | GPGIAPTVKT | GEEVGFVVDA | KTAGKGKVTC |
1700:
VILTPDGTEA | EADVIENEDG | TYDIFYTAAK | PGTYVIYVRF | GGVDIPNSPF |
1750:
TVMATDGEVT | AMEEAPVNAC | PPGFRPWVTE | EAYVPVSDMN | GLGFKPFDLV |
1800:
IPFAVRKGEI | TGTVHMPSGK | KATPEIVDNK | DGTVTVRYAP | TEVGLHEMHI |
1850:
KYRGSHIPES | PLQFYVNYPN | SGSVSAYGPG | LVYGVANKTA | TFTIVTEDAG |
1900:
EGGLDLAIEG | PSKAEISCID | NKDGTCTVTY | LPTLPGDYSI | LVKYNDKHIP |
1950:
GSPFTAKITD | DNRRCSQVKL | GSAADFLLDI | SETDLSTLTA | SIKAPSGRDE |
2000:
PCLLKRLPNN | HIGISFIPRE | VGEHLVSIKK | NGNHVANSPV | SIMVVQSEIG |
2050:
DARRAKVYGQ | GLSEGRTFEM | SDFIVDTRDA | GYGGISLAVE | GPSKVDIQTE |
2100:
DLEDGTCKVS | YFPTVPGVYI | VSTKFADEHV | PGSPFTVKIS | GEGRVRESIT |
2150:
RTSRAPAVAT | VGSICDLNLK | IPEINSSDMS | AHVTSPSGHV | TEAEIVPMGK |
2200:
NSHCVRFVPQ | EMGVHTVSVK | YRGQHVTGSP | FQFTVGPLGE | GGAHKVRAGG |
2250:
PGLERGEAGI | PAEFSIWTRE | AGAGGLSIAV | EGPSKAEITF | DDHKNGSCGV |
2300:
SYIAQEPGNY | EVSIKFNDEH | IPDSPYLVPV | IAPSDDARCL | TVLSLQESGL |
2350:
KVNQPASFAI | RLNGAKGKID | AKVHSPSGAV | EECHVSELEP | DKYAVRFIPH |
2400:
ENGIHTIDVK | FNGSHVVGSP | FKVRVGEPGQ | AGNPALVSAY | GAGLETGTTG |
2450:
IQSEFFINTT | QAGPGTLSVT | IEGPSKVKMD | CQEIPEGYKV | MYTPMAPGNY |
2500:
LIGVKYGGPN | HISRSPFKAK | VTGQRLVSPG | SANETSSILV | ESVTRSSTET |
2550:
CYSAIPKSSS | DASKVTSKGA | GLSKAFVGQK | SSFLVDCSKA | GSNMLLIGVH |
2600:
GPTTPCEEVS | MKHVGKQQYN | VTYVVKERGD | YVLAVKWGEE | HIPGSPFHVT |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rabbit
ELISA Kit for Mouse FLN-B
ELISA Kit for Mouse FLN-B
ELISA Kit for Mouse FLN-B
Polyclonal Antibody for Mouse FLN-B
Polyclonal Antibody for Mouse FLN-B
Polyclonal Antibody for Mouse FLN-B
Monoclonal Antibody for Mouse FLN-B
Monoclonal Antibody for Mouse FLN-B
Monoclonal Antibody for Mouse FLN-B
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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"Lineage-specific biology revealed by a finished genome assembly of the mouse."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1884-2602
strain :
FVB/N .
tissue :
Mammary tumor .
tissue :
Salivary gland .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-1780;SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-2518 AND LYS-2524;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH FAM101A AND FAM101B