AHSP ELISA Kit for Human(Homo sapiens) | EIAab.comAHSP ELISA Kit for Human(Homo sapiens)

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Index > Protein center > AHSP(Gene name) > Human

AHSP (Gene name),

Alpha-hemoglobin-stabilizing protein (Protein name ), AHSP_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

AHSP(EDRF;ERAF);

Protein name:

Alpha-hemoglobin-stabilizing protein;

Alternative:

Erythroid-associated factor;Erythroid differentiation-related factor;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer. Forms an heterodimer with free alpha-hemoglobin. Does not bind beta-hemoglobin nor alpha(2)beta(2) hemoglobin A.

Function:

Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

102

Sequence:

50:

100:

102:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9NZD4

Pfam:

PF09236

KEGG:

hsa:51327

SMR:

Q9NZD4

UniGene:

Hs.274309

MIM:

605821

STRING:

9606.ENSP00000307199

Uniprot:

Q9NZD4

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ELISA Kit for Human Alpha-hemoglobin-stabilizing protein

Cat.:

E0412h

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96T

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ELISA Kit for Human Alpha-hemoglobin-stabilizing protein

Cat.:

E0412m

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96T

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ELISA Kit for Human Alpha-hemoglobin-stabilizing protein

Cat.:

E0412b

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Packing:

96T

CLIA Kit for Human Alpha-hemoglobin-stabilizing protein

Cat.:

U0412h

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MSDS:

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Packing:

96T

CLIA Kit for Human Alpha-hemoglobin-stabilizing protein

Cat.:

U0412m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Alpha-hemoglobin-stabilizing protein

Cat.:

U0412b

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96T

Polyclonal Antibody for Human Alpha-hemoglobin-stabilizing protein

Cat.:

P0412Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Alpha-hemoglobin-stabilizing protein

Cat.:

P0412Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Alpha-hemoglobin-stabilizing protein

Protein for Human Alpha-hemoglobin-stabilizing protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A novel erythroid-specific marker of transmissible spongiform encephalopathies."
Miele G. , Manson J. , Clinton M.
Nat. Med.7:361-364(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
2.

"Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
Zhang Q.-H. , Ye M. , Wu X.-Y. , Ren S.-X. , Zhao M. , Zhao C.-J. , Fu G. , Shen Y. , Fan H.-Y. , Lu G. , Zhong M. , Xu X.-R. , Han Z.-G. , Zhang J.-W. , Tao J. , Huang Q.-H. , Zhou J. , Hu G.-X. , more...
Genome Res.10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Umbilical cord blood.
3.

Michel U. , Schulz-Schaeffer W.
Submitted (2002-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

Finning K. , Anstee D.
Submitted (2002-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
6.

"An abundant erythroid protein that stabilizes free alpha-haemoglobin."
Kihm A.J. , Kong Y. , Hong W. , Russell J.E. , Rouda S. , Adachi K. , Simon M.C. , Blobel G.A. , Weiss M.J.
Nature417:758-763(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
7.

"Biophysical characterization of the alpha-globin binding protein alpha-hemoglobin stabilizing protein."
Gell D. , Kong Y. , Eaton S.A. , Weiss M.J. , Mackay J.P.
J. Biol. Chem.277:40602-40609(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
8.

"Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin."
Feng L. , Gell D.A. , Zhou S. , Gu L. , Kong Y. , Li J. , Hu M. , Yan N. , Lee C. , Rich A.M. , Armstrong R.S. , Lay P.A. , Gow A.J. , Weiss M.J. , Mackay J.P. , Shi Y.
Cell119:629-640(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-90;X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) IN COMPLEX WITH HBA
9.

"NMR structure of the alpha-hemoglobin stabilizing protein: insights into conformational heterogeneity and binding."
Santiveri C.M. , Perez-Canadillas J.M. , Vadivelu M.K. , Allen M.D. , Rutherford T.J. , Watkins N.A. , Bycroft M.
J. Biol. Chem.279:34963-34970(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 2-102 OF WILD TYPE AND MUTANT ALA-30
10.

"Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem."
Feng L. , Zhou S. , Gu L. , Gell D.A. , Mackay J.P. , Weiss M.J. , Gow A.J. , Shi Y.
Nature435:697-701(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) IN COMPLEX WITH HBA

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