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Index > Protein center > BATF(Gene name) > Human
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  • BATF (Gene name),
  • Basic leucine zipper transcriptional factor ATF-like (Protein name ),  BATF_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    BATF;
    Protein name:
    Basic leucine zipper transcriptional factor ATF-like;
    Alternative:
    SF-HT-activated gene 2 protein(SFA-2);B-cell-activating transcription factor(B-ATF);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Forms heterodimers with JUN, JUNB and JUND. Also interacts with IFI35.
    Function:
    Functions as a negative regulator of AP-1 mediated transcription by binding to Jun proteins. Jun/B-ATF heterodimers bind DNA preferentially at the 12-O-tetradecanoylphorbol-13-acetate response element (TRE) (consensus: 5'-TGA[CG]TCA-3') and weaker at the cAMP-responsive region (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), but are transcriptionally inert.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    125
    Sequence:
    50:
    MPHSSDSSDS | SFSRSPPPGK | QDSSDDVRRV | QRREKNRIAA | QKSRQRQTQK | 
    100:
    ADTLHLESED | LEKQNAALRK | EIKQLTEELK | YFTSVLNSHE | PLCSVLAAST | 
    125:
    PSPPEVVYSA | HAFHQPHVSS | PRFQP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    MIM:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Basic leucine zipper transcriptional factor ATF-like
    ELISA Kit for Human Basic leucine zipper transcriptional factor ATF-like
    ELISA Kit for Human Basic leucine zipper transcriptional factor ATF-like
    ELISA Kit for Human Basic leucine zipper transcriptional factor ATF-like
    CLIA Kit for Human Basic leucine zipper transcriptional factor ATF-like
    CLIA Kit for Human Basic leucine zipper transcriptional factor ATF-like
    CLIA Kit for Human Basic leucine zipper transcriptional factor ATF-like
    CLIA Kit for Human Basic leucine zipper transcriptional factor ATF-like
    Polyclonal Antibody for Human Basic leucine zipper transcriptional factor ATF-like
    Polyclonal Antibody for Human Basic leucine zipper transcriptional factor ATF-like
    Polyclonal Antibody for Human Basic leucine zipper transcriptional factor ATF-like
    Polyclonal Antibody for Human Basic leucine zipper transcriptional factor ATF-like
    Monoclonal Antibody for Human Basic leucine zipper transcriptional factor ATF-like
    Monoclonal Antibody for Human Basic leucine zipper transcriptional factor ATF-like
    Monoclonal Antibody for Human Basic leucine zipper transcriptional factor ATF-like
    Monoclonal Antibody for Human Basic leucine zipper transcriptional factor ATF-like
    Protein for Human Basic leucine zipper transcriptional factor ATF-like
    Protein for Human Basic leucine zipper transcriptional factor ATF-like
    Protein for Human Basic leucine zipper transcriptional factor ATF-like
    Protein for Human Basic leucine zipper transcriptional factor ATF-like

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    Precision
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    References
    1. 1.
      "B-ATF: a novel human bZIP protein that associates with members of the AP-1 transcription factor family."
      Dorsey M.J. , Tae H.-J. , Sollenberger K.G. , Mascarenhas N.T. , Johansen L.M. , Taparowsky E.J.
      Oncogene11:2255-2265(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH JUN PROTEINS;TISSUE SPECIFICITY
    2. 2.
      "SFA-2, a novel bZIP transcription factor induced by human T-cell leukemia virus type I, is highly expressed in mature lymphocytes."
      Hasegawa H. , Utsunomiya Y. , Kishimoto K. , Tange Y. , Yasukawa M. , Fujita S.
      Biochem. Biophys. Res. Commun.222:164-170(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
    3. 3.
      "Genomic organization of human B-ATF, a target for regulation by EBV and HTLV-1."
      Meyer N.P. , Johansen L.M. , Tae H.-J. , Budde P.P. , Williams K.L. , Taparowsky E.J.
      Mamm. Genome9:849-852(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "The DNA sequence and analysis of human chromosome 14."
      Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
      Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Melanoma.
    6. 6.
      "IFP 35 forms complexes with B-ATF, a member of the AP1 family of transcription factors."
      Wang X. , Johansen L.M. , Tae H.-J. , Taparowsky E.J.
      Biochem. Biophys. Res. Commun.229:316-322(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IFI35
    7. 7.
      "B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos."
      Echlin D.R. , Tae H.-J. , Mitin N. , Taparowsky E.J.
      Oncogene19:1752-1763(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
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