Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > BECN1P1(Gene name) > Human
  • Add your favorite
  • BECN1P1 (Gene name),
  • Beclin-2 (Protein name ),  BECN2_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    BECN1P1(BECN2);
    Protein name:
    Beclin-2;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with ATG14, AMBRA1, UVRAG and PIK3C3/VPS34; interaction is not disrupted by starvation. Does not interact with KIAA0226/Rubicon. Interacts (via N-terminus) with GPRASP1/GASP1; the interaction is direct.
    Function:
    Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    431
    Sequence:
    50:
    MSSIRFLCQR | CHQALKLSGS | SESRSLPAAP | APTSGQAEPG | DTREPGVTTR | 
    100:
    EVTDAEEQQD | GASSRSPPGD | GSVSKGHANI | FTLLGELGAM | HMLSSIQKAA | 
    150:
    GDIFDIVSGQ | AVVDHPLCEE | CTDSLLEQLD | IQLALTEADS | QNYQRCLETG | 
    200:
    ELATSEDEAA | ALRAELRDLE | LEEARLVQEL | EDVDRNNARA | AADLQAAQAE | 
    250:
    AAELDQQERQ | HYRDYSALKR | QQLELLDQLG | NVENQLQYAR | VQRDRLKEIN | 
    300:
    CFTATFEIWV | EGPLGVINNF | RLGRLPTVRV | GWNEINTAWG | QAALLLLTLA | 
    350:
    NTIGLQFQRY | RLIPCGNHSY | LKSLTDDRTE | LPLFCYGGQD | VFLNNKYDRA | 
    400:
    MVAFLDCMQQ | FKEEAEKGEL | GLSLPYGIQV | ETGLMEDVGG | RGECYSIRTH | 
    431:
    LNTQELWTKA | LKFMLINFKW | SLIWVASRYQ | K
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Beclin-2
    CLIA Kit for Human Beclin-2
    Polyclonal Antibody for Human Beclin-2
    Monoclonal Antibody for Human Beclin-2
    Protein for Human Beclin-2

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism."
      He C. , Wei Y. , Sun K. , Li B. , Dong X. , Zou Z. , Liu Y. , Kinch L.N. , Khan S. , Sinha S. , Xavier R.J. , Grishin N.V. , Xiao G. , Eskelinen E.L. , Scherer P.E. , Whistler J.L. , Levine B.
      Cell154:1085-1099(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH ATG14; AMBRA1; GPRASP1; UVRAG AND PIK3C3;TISSUE SPECIFICITY;MUTAGENESIS OF ILE-80
    2. 2.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    Product Feedback Wall
    Hot Genes
    Top Searches
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter