Gene name:
BHLHE22 (BHLHB5;TNRC20) ;
Protein name:
Class E basic helix-loop-helix protein 22 (bHLHe22) ;
Alternative:
Trinucleotide repeat-containing gene 20 protein ;Class B basic helix-loop-helix protein 5 (bHLHb5) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MERGMHLGAA | AAGEDDLFLH | KSLSASTSKR | LEAAFRSTPP | GMDLSLAPPP |
100:
RERPASSSSS | PLGCFEPADP | EGAGLLLPPP | GGGGGGSAGS | GGGGGGGVGV |
150:
PGLLVGSAGV | GGDPSLSSLP | AGAALCLKYG | ESASRGSVAE | SSGGEQSPDD |
200:
DSDGRCELVL | RAGVADPRAS | PGAGGGGAKA | AEGCSNAHLH | GGASVPPGGL |
250:
GGGGGGGSSS | GSSGGGGGSG | SGSGGSSSSS | SSSSKKSKEQ | KALRLNINAR |
300:
ERRRMHDLND | ALDELRAVIP | YAHSPSVRKL | SKIATLLLAK | NYILMQAQAL |
350:
EEMRRLVAYL | NQGQAISAAS | LPSSAAAAAA | AAALHPALGA | YEQAAGYPFS |
381:
AGLPPAASCP | EKCALFNSVS | SSLCKQCTEK | P
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Mouse
ELISA Kit for Human bHLHe22
ELISA Kit for Human bHLHe22
ELISA Kit for Human bHLHe22
CLIA Kit for Human bHLHe22
CLIA Kit for Human bHLHe22
CLIA Kit for Human bHLHe22
Polyclonal Antibody for Human bHLHe22
Polyclonal Antibody for Human bHLHe22
Polyclonal Antibody for Human bHLHe22
Monoclonal Antibody for Human bHLHe22
Monoclonal Antibody for Human bHLHe22
Monoclonal Antibody for Human bHLHe22
Protein for Human bHLHe22
Protein for Human bHLHe22
Protein for Human bHLHe22
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];TISSUE SPECIFICITY
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION