Gene name:
BHLHE41 (BHLHB3;DEC2;SHARP1) ;
Protein name:
Class E basic helix-loop-helix protein 41 (bHLHe41) ;
Alternative:
Differentially expressed in chondrocytes protein 2 (hDEC2) ;Class B basic helix-loop-helix protein 3 (bHLHb3) ;Enhancer-of-split and hairy-related protein 1 (SHARP-1) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
May be a transcriptional repressor that represses both basal and activated transcription.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MDEGIPHLQE | RQLLEHRDFI | GLDYSSLYMC | KPKRSMKRDD | TKDTYKLPHR |
100:
LIEKKRRDRI | NECIAQLKDL | LPEHLKLTTL | GHLEKAVVLE | LTLKHLKALT |
150:
ALTEQQHQKI | IALQNGERSL | KSPIQSDLDA | FHSGFQTCAK | EVLQYLSRFE |
200:
SWTPREPRCV | QLINHLHAVA | TQFLPTPQLL | TQQVPLSKGT | GAPSAAGSAA |
250:
APCLERAGQK | LEPLAYCVPV | IQRTQPSAEL | AAENDTDTDS | GYGGEAEARP |
300:
DREKGKGAGA | SRVTIKQEPP | GEDSPAPKRM | KLDSRGGGSG | GGPGGGAAAA |
350:
AAALLGPDPA | AAAALLRPDA | ALLSSLVAFG | GGGGAPFPQP | AAAAAPFCLP |
400:
FCFLSPSAAA | AYVQPFLDKS | GLEKYLYPAA | AAAPFPLLYP | GIPAPAAAAA |
450:
AAAAAAAAAA | AFPCLSSVLS | PPPEKAGAAA | ATLLPHEVAP | LGAPHPQHPH |
482:
GRTHLPFAGP | REPGNPESSA | QEDPSQPGKE | AP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human bHLHe41
ELISA Kit for Human bHLHe41
CLIA Kit for Human bHLHe41
CLIA Kit for Human bHLHe41
Polyclonal Antibody for Human bHLHe41
Polyclonal Antibody for Human bHLHe41
Monoclonal Antibody for Human bHLHe41
Monoclonal Antibody for Human bHLHe41
Protein for Human bHLHe41
Protein for Human bHLHe41
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Molecular cloning and characterization of DEC2, a new member of basic helix-loop-helix proteins."
Fujimoto K.
,
Shen M.
,
Noshiro M.
,
Matsubara K.
,
Shingu S.
,
Honda K.
,
Yoshida E.
,
Suardita K.
,
Matsuda Y.
,
Kato Y.
Biochem. Biophys. Res. Commun.280:164-171(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.
Mural R.J.
,
Istrail S.
,
Sutton G.G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
,
Walenz B.
,
Shatkay H.
,
Dew I.
,
Miller J.R.
,
Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
5.
"A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation."
Kawamoto T.
,
Noshiro M.
,
Sato F.
,
Maemura K.
,
Takeda N.
,
Nagai R.
,
Iwata T.
,
Fujimoto K.
,
Furukawa M.
,
Miyazaki K.
,
Honma S.
,
Honma K.I.
,
Kato Y.
Biochem. Biophys. Res. Commun.313:117-124(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;HETERODIMERIZATION WITH BHLHE40/DEC1
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
8.
"DEC1 modulates the circadian phase of clock gene expression."
Nakashima A.
,
Kawamoto T.
,
Honda K.K.
,
Ueshima T.
,
Noshiro M.
,
Iwata T.
,
Fujimoto K.
,
Kubo H.
,
Honma S.
,
Yorioka N.
,
Kohno N.
,
Kato Y.
Mol. Cell. Biol.28:4080-4092(2008)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH RXRA;MUTAGENESIS OF 70-LEU-LEU-71
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT ARG-384;ASSOCIATION OF VARIANT ARG-384 WITH SHORT SLEEP PHENOTYPE