Protein name:
Bleomycin hydrolase (BH;BLM hydrolase;BMH) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Function:
The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MSSSGLNSEK | VAALIQKLNS | DPQFVLAQNV | GTTHDLLDIC | LKRATVQRAQ |
100:
HVFQHAVPQE | GKPITNQKSS | GRCWIFSCLN | VMRLPFMKKL | NIEEFEFSQS |
150:
YLFFWDKVER | CYFFLSAFVD | TAQRKEPEDG | RLVQFLLMNP | ANDGGQWDML |
200:
VNIVEKYGVI | PKKCFPESYT | TEATRRMNDI | LNHKMREFCI | RLRNLVHSGA |
250:
TKGEISATQD | VMMEEIFRVV | CICLGNPPET | FTWEYRDKDK | NYQKIGPITP |
300:
LEFYREHVKP | LFNMEDKICL | VNDPRPQHKY | NKLYTVEYLS | NMVGGRKTLY |
350:
NNQPIDFLKK | MVAASIKDGE | AVWFGCDVGK | HFNSKLGLSD | MNLYDHELVF |
400:
GVSLKNMNKA | ERLTFGESLM | THAMTFTAVS | EKDDQDGAFT | KWRVENSWGE |
450:
DHGHKGYLCM | TDEWFSEYVY | EVVVDRKHVP | EEVLAVLEQE | PIILPAWDPM |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Rat
Human
Mouse
Rabbit
Polyclonal Antibody for Human BH
Polyclonal Antibody for Human BH
Polyclonal Antibody for Human BH
Polyclonal Antibody for Human BH
Polyclonal Antibody for Human BH
Monoclonal Antibody for Human BH
Monoclonal Antibody for Human BH
Monoclonal Antibody for Human BH
Monoclonal Antibody for Human BH
Monoclonal Antibody for Human BH
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;VARIANT VAL-443
tissue :
Lung .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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more...
Nat. Genet.36:40-45(2004)
[
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Amygdala .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
6.
Mural R.J.
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Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Lymph .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 292-455;VARIANT VAL-443
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-391;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS)