Breast cancer metastasis-suppressor 1 homolog (Protein name
), BRMS1_MOUSE from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Gene name:
Brms1;
Protein name:
Breast cancer metastasis-suppressor 1 homolog;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with SNX6, HDAC1 and RELA. Interacts with ARID4A. Identified in mSin3A corepressor complexes together with SIN3A, SIN3B, RBBP4, RBBP7, SAP30, SUDS3, ARID4A, HDAC1 and HDAC2.
Function:
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis.
Monoclonal Antibody for Mouse Breast cancer metastasis-suppressor 1 homolog
Monoclonal Antibody for Mouse Breast cancer metastasis-suppressor 1 homolog
Monoclonal Antibody for Mouse Breast cancer metastasis-suppressor 1 homolog
Monoclonal Antibody for Mouse Breast cancer metastasis-suppressor 1 homolog
Protein for Mouse Breast cancer metastasis-suppressor 1 homolog
Protein for Mouse Breast cancer metastasis-suppressor 1 homolog
Protein for Mouse Breast cancer metastasis-suppressor 1 homolog
Protein for Mouse Breast cancer metastasis-suppressor 1 homolog
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Brms1: murine homolog of human breast metastasis suppressor gene-1 (BRMS1)." Samant R.S.
,
Debies M.T.
,
Welch D.R.
Submitted (2000-02) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [MRNA]