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Index > Protein center > CASP3(Gene name) > Pig
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  • CASP3 (Gene name),
  • Caspase-3 (Protein name ),  CASP3_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CASP3;
    Protein name:
    Caspase-3(CASP-3);
    Alternative:

    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 17 kDa (p17) and a 12 kDa (p12) subunit (By similarity). Subunit p17 interacts with asfivirus A224L protein.
    Function:
    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    277
    Sequence:
    50:
    MENNKTSVDS | KSIKTLETKI | LHGSKSMDSG | ISLDVSYKMD | YPEMGLCIII | 
    100:
    NNKNFDKNTG | MACRSGTDVD | AANLRETFTN | LKYEVRNKND | LTREEILELM | 
    150:
    HSVSKEDHSK | RSSFICVLLS | HGEEGKIFGT | NGPVDLKKLT | SFFRGDCCRT | 
    200:
    LTGKPKLFII | QACRGTELDC | GIETDSGTED | DMACQKIPVE | ADFLYAYSTA | 
    250:
    PGYYSWRNSK | DGSWFIQSLC | AALKQYVHKL | ELMHILTRVN | RKVAVEFESF | 
    277:
    STDSTFHAKK | QIPCIVSMLT | KELYFYH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Pig CASP-3
    Cat.:
    E0626b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig CASP-3
    Cat.:
    E0626h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig CASP-3
    Cat.:
    E0626m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig CASP-3
    Cat.:
    E0626r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig CASP-3
    Cat.:
    E0626p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig CASP-3
    MSDS:
    Please sign in first.
    ELISA Kit for Pig CASP-3
    Cat.:
    E0626d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig CASP-3
    MSDS:
    Please sign in first.
    CLIA Kit for Pig CASP-3
    Cat.:
    U0626h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig CASP-3
    Cat.:
    U0626p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig CASP-3
    Cat.:
    U0626m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig CASP-3
    Cat.:
    U0626d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig CASP-3
    Cat.:
    U0626r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig CASP-3
    Cat.:
    U0626b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Pig CASP-3
    Cat.:
    P0626Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig CASP-3
    Polyclonal Antibody for Pig CASP-3
    Cat.:
    P0626Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig CASP-3
    Cat.:
    P0626Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig CASP-3
    Polyclonal Antibody for Pig CASP-3
    Polyclonal Antibody for Pig CASP-3
    Monoclonal Antibody for Pig CASP-3
    Monoclonal Antibody for Pig CASP-3
    Monoclonal Antibody for Pig CASP-3
    Monoclonal Antibody for Pig CASP-3
    Monoclonal Antibody for Pig CASP-3
    Monoclonal Antibody for Pig CASP-3
    Monoclonal Antibody for Pig CASP-3
    Protein for Pig CASP-3
    Protein for Pig CASP-3
    Protein for Pig CASP-3
    Protein for Pig CASP-3
    Protein for Pig CASP-3
    Protein for Pig CASP-3
    Protein for Pig CASP-3
    Cat.:
    R0626h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

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    References
    1. 1.
      "Porcine caspase-3: its cloning and activity during apoptosis of PK15 cells induced by porcine Fas ligand."
      Muneta Y. , Shimojima Y. , Mori Y.
      J. Interferon Cytokine Res.21:409-415(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "African swine fever virus IAP homologue inhibits caspase activation and promotes cell survival in mammalian cells."
      Nogal M.L. , Gonzalez de Buitrago G. , Rodriguez C. , Cubelos B. , Carrascosa A.L. , Salas M.L. , Revilla Y.
      J. Virol.75:2535-2543(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ASFIVIRUS A224L
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