Protein name:
Complement C3 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
C3 precursor is first processed by the removal of 4 Arg residues, forming two chains, beta and alpha, linked by a disulfide bond. C3 convertase activates C3 by cleaving the alpha chain, releasing C3a anaphylatoxin and generating C3b (beta chain + alpha' chain). C3dg interacts with CR2 (via the N-terminal Sushi domains 1 and 2). Interacts with VSIG4 (By similarity). Interacts with bovine herpes virus 1 (BHV-1) envelope glycoprotein C; this interaction inhibits the activation of the complement system.
Function:
Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Subcellular Location:
Secreted
Protein Attributes:
50:
MKPTSGPSLL | LLLLASLPMA | LGNPMYSMIT | PNILRLESEE | TVVLEAHGGQ |
100:
GTIQVSVTVH | DFPAKKQVLS | NENTQLNSNN | GYLSTVTIKI | PASKELKSDK |
150:
GHKFVTVVAT | FGNVQVEKVV | LISLQSGYLF | IQTDKTIYTP | GSTVLYRVFT |
200:
VDHKLLPVGQ | TVFITIETPD | GIPVKRDSKS | SQNQFGILTL | SWNIPELVNM |
250:
GVWKIKAYYE | DSPQQVFSAE | FEVKEYVLPS | FEVQLEPEEK | FYYIDDPDGL |
300:
KVNIIARFLY | GEQVDGTAFV | IFGVQDGDRR | ISLTHSLTRV | PINDGNGEAI |
350:
LKRQVLLNGV | QPSRADALVG | KSIYVSATVI | LQSGSDMVEA | ERTGIPIVTS |
400:
PYQIHFTKTP | KFFKPAMPFD | LMVYVTNPDG | SPARHIPVVT | QGSNVQSLTQ |
450:
DDGVAKLSIN | TQNKRDPLTI | TVRTKKDNIP | EGRQATRTMQ | ALPYNTQGNS |
500:
NNYLHLSVPR | VELKPGETLN | VNFHLRTDPG | EQAKIRYYTY | MIMNKGKLLK |
550:
VGRQYREPGQ | DLVVLPLTIT | SDFIPSFRLV | AYYTLINAKG | QREVVADSVW |
600:
VDVKDSCMGT | LVVKNGGKEE | KHHRPGQQIT | LKIEADQGAR | VGLVAVDKGV |
650:
FVLNKKNKLT | QRKIWDVVEK | ADIGCTPGSG | RNYAGVFTDA | GLTLKTSQGL |
700:
ETQQRADPQC | PQPATRRRRS | VQLMEKRMDK | AGQYSSDLRK | CCEDGMRDNP |
750:
MKFPCQRRAQ | FILQGDACVK | AFLDCCEYIT | QLRQQHSRDG | ALELARSDLD |
800:
DDIIPEEDII | SRSQFPESWL | WTVIEDLKQA | DKNGISTKLM | NVFLKDSITT |
850:
WEILAVSLSD | KKGICVADPY | EVTVMQDFFI | DLRLPYSVVR | NEQVEIRAIL |
900:
YNYREAENLK | VRVELLYNPA | FCSLATAKKR | HQQTITIPAR | SSVAVPYVIV |
950:
PLKIGLHEVE | VKAAVYNHFI | SDGVKKTLKV | VPEGVRVNKT | VAVRTLNPEH |
1000:
LGQGGVQREE | VPAADLSDQV | PDTESETKIL | LQGTPVAQMT | EDAIDGERLK |
1050:
HLIQTPSGCG | EQNMIGMTPT | VIAVHYLDST | DQWEKFGLEK | RQESLELIRK |
1100:
GYTQQLAFRQ | KSSAYAAFQY | RPPSTWLTAY | VVKVFALAAN | LIAIDSKDLC |
1150:
ETVKWLILEK | QKPDGIFQED | GPVIHQEMIG | GFRDTREKDV | SLTAFVLIAL |
1200:
HEAKDICEAQ | VNSLGRSIAK | AGDFLENHYR | ELRRPYTVAI | AAYALALLGK |
1250:
LEGDRLTKFL | NTAKEKNRWE | EPNQKLYNVE | ATSYALLALL | ARKDYDTTPP |
1300:
VVRWLNEQRY | YGGGYGSTQA | TFMVFQALAQ | YQKDVPDHKE | LNLDVSIQLP |
1350:
SRNSAVRHRI | LWESASLLRS | EETKENERFT | VKAEGKGQGT | LSVVTVYHAK |
1400:
LKGKVSCKKF | DLRVSIRPAP | ETVKKPQDAK | GSMILDICTK | YLGDQDATMS |
1450:
ILDISMMTGF | SPDVEDLKTL | STGVDRYISK | YEMNRDSNKN | TLIIYLDKVS |
1500:
HTVEDCLSFK | VHQYFNVGLI | QPGAVKVYSY | YNLDETCIRF | YHPDKEDGML |
1550:
SKLCHKDTCR | CAEENCFMHH | TEKEVTLEDR | LDKACEPGVD | YVYKTRLIQK |
1600:
KLEDDFDEYI | MVIENIIKSG | SDEVQVKQER | KFISHIKCRE | ALKLKEGAHY |
1650:
LVWGVSSDLW | GEKPKISYII | GKDTWVELWP | EAEECQDEEN | QKQCEDLANF |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Pig
Rat
Bovine
Rabbit
ELISA Kit for Bovine Complement C3
ELISA Kit for Bovine Complement C3
ELISA Kit for Bovine Complement C3
ELISA Kit for Bovine Complement C3
ELISA Kit for Bovine Complement C3
ELISA Kit for Bovine Complement C3
CLIA Kit for Bovine Complement C3
CLIA Kit for Bovine Complement C3
CLIA Kit for Bovine Complement C3
CLIA Kit for Bovine Complement C3
CLIA Kit for Bovine Complement C3
CLIA Kit for Bovine Complement C3
Polyclonal Antibody for Bovine Complement C3
Polyclonal Antibody for Bovine Complement C3
Polyclonal Antibody for Bovine Complement C3
Polyclonal Antibody for Bovine Complement C3
Polyclonal Antibody for Bovine Complement C3
Polyclonal Antibody for Bovine Complement C3
Monoclonal Antibody for Bovine Complement C3
Monoclonal Antibody for Bovine Complement C3
Monoclonal Antibody for Bovine Complement C3
Monoclonal Antibody for Bovine Complement C3
Monoclonal Antibody for Bovine Complement C3
Monoclonal Antibody for Bovine Complement C3
Protein for Bovine Complement C3
Protein for Bovine Complement C3
Protein for Bovine Complement C3
Protein for Bovine Complement C3
Protein for Bovine Complement C3
Protein for Bovine Complement C3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF C3
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Crossbred X Angus .
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH BHV-1 GLYCOPROTEIN C