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Index > Protein center > F10(Gene name) > Bovine
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  • F10 (Gene name),
  • Coagulation factor X (Protein name ),  FA10_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    F10;
    Protein name:
    Coagulation factor X;
    Alternative:
    Stuart factor;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.
    Function:
    Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    492
    Sequence:
    50:
    MAGLLHLVLL | STALGGLLRP | AGSVFLPRDQ | AHRVLQRARR | ANSFLEEVKQ | 
    100:
    GNLERECLEE | ACSLEEAREV | FEDAEQTDEF | WSKYKDGDQC | EGHPCLNQGH | 
    150:
    CKDGIGDYTC | TCAEGFEGKN | CEFSTREICS | LDNGGCDQFC | REERSEVRCS | 
    200:
    CAHGYVLGDD | SKSCVSTERF | PCGKFTQGRS | RRWAIHTSED | ALDASELEHY | 
    250:
    DPADLSPTES | SLDLLGLNRT | EPSAGEDGSQ | VVRIVGGRDC | AEGECPWQAL | 
    300:
    LVNEENEGFC | GGTILNEFYV | LTAAHCLHQA | KRFTVRVGDR | NTEQEEGNEM | 
    350:
    AHEVEMTVKH | SRFVKETYDF | DIAVLRLKTP | IRFRRNVAPA | CLPEKDWAEA | 
    400:
    TLMTQKTGIV | SGFGRTHEKG | RLSSTLKMLE | VPYVDRSTCK | LSSSFTITPN | 
    450:
    MFCAGYDTQP | EDACQGDSGG | PHVTRFKDTY | FVTGIVSWGE | GCARKGKFGV | 
    492:
    YTKVSNFLKW | IDKIMKARAG | AAGSRGHSEA | PATWTVPPPL | PL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Coagulation factor X
    Cat.:
    E0834h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine Coagulation factor X
    Cat.:
    E0834r
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    Packing:
    96T
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    ELISA Kit for Bovine Coagulation factor X
    MSDS:
    Please sign in first.
    ELISA Kit for Bovine Coagulation factor X
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    E0834m
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    Packing:
    96T
    ELISA Kit for Bovine Coagulation factor X
    Cat.:
    E0834b
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    MSDS:
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    96T
    ELISA Kit for Bovine Coagulation factor X
    Cat.:
    E0834c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor X
    Cat.:
    U0834m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor X
    Cat.:
    U0834b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor X
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine Coagulation factor X
    Cat.:
    U0834c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor X
    Cat.:
    U0834r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Bovine Coagulation factor X
    Cat.:
    U0834h
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    MSDS:
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    Packing:
    96T
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    Polyclonal Antibody for Bovine Coagulation factor X
    Polyclonal Antibody for Bovine Coagulation factor X
    Polyclonal Antibody for Bovine Coagulation factor X
    Cat.:
    P0834Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Coagulation factor X
    Cat.:
    P0834Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Coagulation factor X
    Polyclonal Antibody for Bovine Coagulation factor X
    Cat.:
    P0834Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Coagulation factor X
    Monoclonal Antibody for Bovine Coagulation factor X
    Monoclonal Antibody for Bovine Coagulation factor X
    Monoclonal Antibody for Bovine Coagulation factor X
    Monoclonal Antibody for Bovine Coagulation factor X
    Monoclonal Antibody for Bovine Coagulation factor X
    Protein for Bovine Coagulation factor X
    Protein for Bovine Coagulation factor X
    Protein for Bovine Coagulation factor X
    Protein for Bovine Coagulation factor X
    Protein for Bovine Coagulation factor X
    Protein for Bovine Coagulation factor X

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    References
    1. 1.
      "Blood coagulation factor X mRNA encodes a single polypeptide chain containing a prepro leader sequence."
      Fung M.R. , Campbell R.M. , McGillivray R.T.A.
      Nucleic Acids Res.12:4481-4492(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-487
    2. 2.
      "Amino acid sequence of the light chain of bovine factor X1 (Stuart factor)."
      Enfield D.L. , Ericsson L.H. , Fujikawa K. , Walsh K.A. , Neurath H. , Titani K.
      Biochemistry19:659-667(1980) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 41-180;GAMMA-CARBOXYGLUTAMATION AT GLU-46; GLU-47; GLU-54; GLU-56; GLU-59; GLU-60; GLU-65; GLU-66; GLU-69; GLU-72; GLU-75 AND GLU-79
    3. 3.
      "The occurrence of beta-hydroxyaspartic acid in the vitamin K-dependent blood coagulation zymogens."
      McMullen B.A. , Fujikawa K. , Kisiel W.
      Biochem. Biophys. Res. Commun.115:8-14(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HYDROXYLATION AT ASP-103
    4. 4.
      "Bovine factor X1 (Stuart factor): amino-acid sequence of heavey chain."
      Titani K. , Fujikawa K. , Enfield D.L. , Ericsson L.H. , Walsh K.A. , Neurath H.
      Proc. Natl. Acad. Sci. U.S.A.72:3082-3086(1975) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 183-492;GLYCOSYLATION AT ASN-218 AND THR-485;DISULFIDE BONDS
    5. 5.
      "Identification of O-linked oligosaccharide chains in the activation peptides of blood coagulation factor X. The role of the carbohydrate moieties in the activation of factor X."
      Inoue K. , Morita T.
      Eur. J. Biochem.218:153-163(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 183-233;GLYCOSYLATION AT THR-208
    6. 6.
      "Bovine factor X 1a (activated Stuart factor). Evidence of homology with mammalian serine proteases."
      Titani K. , Hermodson M.A. , Fujikawa K. , Ericsson L.H. , Walsh K.A. , Neurath H. , Davie E.W.
      Biochemistry11:4899-4903(1972) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACTIVE SITE
    7. 7.
      "Activation of bovine factor X (Stuart factor): conversion of factor Xa-alpha to factor Xa-beta."
      Fujikawa K. , Titani K. , Davie E.W.
      Proc. Natl. Acad. Sci. U.S.A.72:3359-3363(1975) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
    8. 8.
      "Calcium-binding properties of bovine factor X lacking the gamma-carboxyglutamic acid-containing region."
      Sugo T. , Bjoerk I. , Holmgren A. , Stenflo J.
      J. Biol. Chem.259:5705-5710(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CALCIUM-BINDING
    9. 9.
      "Localization of the structural difference between bovine blood coagulation factors X1 and X2 to tyrosine 18 in the activation peptide."
      Morita T. , Jackson C.M.
      J. Biol. Chem.261:4008-4014(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SULFATION AT TYR-200
    10. 10.
      "1H NMR assignment and secondary structure of the Ca2(+)-free form of the amino-terminal epidermal growth factor like domain in coagulation factor X."
      Selander M. , Persson E. , Stenflo J. , Drakenberg T.
      Biochemistry29:8111-8118(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 85-126
    11. 11.
      "Three-dimensional structure of the apo form of the N-terminal EGF-like module of blood coagulation factor X as determined by NMR spectroscopy and simulated folding."
      Ullner M. , Selander M. , Persson E. , Stenflo J. , Drakenberg T. , Teleman O.
      Biochemistry31:5974-5983(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 85-126
    12. 12.
      "How an epidermal growth factor (EGF)-like domain binds calcium. High resolution NMR structure of the calcium form of the NH2-terminal EGF-like domain in coagulation factor X."
      Selander-Sunnerhagen M. , Ullner M. , Persson E. , Teleman O. , Stenflo J. , Drakenberg T.
      J. Biol. Chem.267:19642-19649(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 85-126
    13. 13.
      "The relative orientation of Gla and EGF domains in coagulation factor X is altered by Ca2+ binding to the first EGF domain. A combined NMR-small angle X-ray scattering study."
      Sunnerhagen M. , Olah G.A. , Stenflo J. , Forsen S. , Drakenberg T. , Trewhella J.
      Biochemistry35:11547-11559(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 41-126
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