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Index > Protein center > Sparc(Gene name) > Rat
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  • Sparc (Gene name),
  • SPARC (Protein name ),  SPRC_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Sparc;
    Protein name:
    SPARC;
    Alternative:
    Osteonectin(ON);Basement-membrane protein 40(BM-40);Secreted protein acidic and rich in cysteine;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
    Subcellular Location:
    Secreted extracellular space extracellular matrix basement membrane In or around the basement membrane.
    Protein Attributes:
    Sequence length:
    301
    Sequence:
    50:
    MRAWIFFLLC | LAGRALAAPQ | TEAAEEMVAE | ETVVEETGLP | VGANPVQVEM | 
    100:
    GEFEEGAEET | VEEVVAENPC | QNHHCKHGKV | CELDESNTPM | CVCQDPTSCP | 
    150:
    APIGEFEKVC | SNDNKTFDSS | CHFFATKCTL | EGTKKGHKLH | LDYIGPCKYI | 
    200:
    APCLDSELTE | FPLRMRDWLK | NVLVTLYERD | EGNNLLTEKQ | KLRVKKIHEN | 
    250:
    EKRLEAGDHP | VELLARDFEK | NYNMYIFPVH | WQFGQLDQHP | IDGYLSHTEL | 
    300:
    APLRAPLIPM | EHCTTRFFET | CDLDNDKYIA | LEEWAGCFGI | KEQDINKDLV | 
    301:
    I
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    KEGG:
    UniGene:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat SPARC
    Cat.:
    E0791h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat SPARC
    Cat.:
    E0791m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat SPARC
    Cat.:
    E0791r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Rat SPARC
    Cat.:
    E0791b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Rat SPARC
    Cat.:
    E0791p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat SPARC
    Cat.:
    E0791c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat SPARC
    MSDS:
    Please sign in first.
    CLIA Kit for Rat SPARC
    Cat.:
    U0791b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SPARC
    Cat.:
    U0791p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SPARC
    Cat.:
    U0791c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SPARC
    Cat.:
    U0791r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat SPARC
    MSDS:
    Please sign in first.
    CLIA Kit for Rat SPARC
    Cat.:
    U0791m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat SPARC
    Cat.:
    U0791h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Rat SPARC
    Polyclonal Antibody for Rat SPARC
    Cat.:
    P0791Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat SPARC
    Polyclonal Antibody for Rat SPARC
    Polyclonal Antibody for Rat SPARC
    Cat.:
    P0791Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat SPARC
    Polyclonal Antibody for Rat SPARC
    Cat.:
    P0791Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat SPARC
    Monoclonal Antibody for Rat SPARC
    Monoclonal Antibody for Rat SPARC
    Monoclonal Antibody for Rat SPARC
    Monoclonal Antibody for Rat SPARC
    Monoclonal Antibody for Rat SPARC
    Monoclonal Antibody for Rat SPARC
    Protein for Rat SPARC
    Protein for Rat SPARC
    Protein for Rat SPARC
    Protein for Rat SPARC
    Protein for Rat SPARC
    Protein for Rat SPARC
    Protein for Rat SPARC

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    References
    1. 1.
      "Regional differences in expression of osteonectin mRNA after administration of cadmium to rats."
      Lee M.J. , Saijoh K. , Nestler E.J. , Duman R.S. , Sumino K.
      Arch. Toxicol.69:590-595(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Wistar.
      tissue: Kidney.
    2. 2.
      "Osteonectin RNA and collagen alpha1(I) RNA in the developing rat maxilla."
      Liao H. , Brandsten C. , Lundmark C. , Christersson C. , Wurtz T.
      Eur. J. Oral Sci.106:418-423(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Bone.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Prostate.
    4. 4.
      "Purification of a calcium binding protein (rat SPARC) from primary Sertoli cell-enriched culture medium."
      Cheng C.Y.
      Biochem. Biophys. Res. Commun.167:1393-1399(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 18-34;CALCIUM-BINDING;SUBCELLULAR LOCATION
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