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Index > Protein center > Cngb3(Gene name) > Mouse
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  • Cngb3 (Gene name),
  • Cyclic nucleotide-gated cation channel beta-3 (Protein name ),  CNGB3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    Cngb3(Cng6);
    Protein name:
    Cyclic nucleotide-gated cation channel beta-3;
    Alternative:
    Cyclic nucleotide-gated cation channel modulatory subunit;Cone photoreceptor cGMP-gated channel subunit beta;Cyclic nucleotide-gated channel subunit CNG6;Cyclic nucleotide-gated channel beta-3(CNG channel beta-3);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterooligomeric complex with CNGA3.
    Function:
    Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones (By similarity). Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGA3.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    694
    Sequence:
    50:
    MLKSLTVKFN | KVNPMEGRME | KKLCPNLSSL | SQPTIAQGDN | QSEKEPLRSR | 
    100:
    TPITFEKSHS | KEDNSTGENS | LRDFTPNPDP | ECRAELTRTM | AEMEKTRTGK | 
    150:
    ERPVSFKTKV | LETSIINEYT | DAHLHNLVER | MRERTALYKK | TLTEEENFPE | 
    200:
    VEASSQTAMS | TNISPKQENN | SKLKEHQDTF | SFKPQRVPVK | EHLRRMILPR | 
    250:
    SIDSYTDRVY | LLWLLLVTIA | YNWNCWLLPV | RLVFPCQTPD | NKNYWIITDI | 
    300:
    VCDIIYLCDI | LLIQPRLQFV | RGGEIIVDSN | ELKRNYRSST | KFRMDVASLL | 
    350:
    PFEVLYIFFG | VNPIFRANRI | LKYTSFFEFN | HHLESIMDKA | YVYRVIRTTG | 
    400:
    YLLFLLHINA | CVYYWASDYE | GIGSTKWVYN | GEGNKYLRCF | YWAVRTLITI | 
    450:
    GGLPEPQTSF | EIVFQFLNFF | SGVFVFSSLI | GQMRDVIGAA | TANQNYFQAC | 
    500:
    MDHIIAYMNK | YSIPQSVQYR | VRTWLEYTWN | SQRILDESNL | LENLPTAMQL | 
    550:
    SIALDINFSI | IDKVELFKGC | DTQMIYDLLL | RLKSTIYLPG | DFVCKKGEIG | 
    600:
    KEMYIIKHGE | VQVLGGPDGA | QVLVTLKAGS | VFGEISLLAK | GGGNRRTADV | 
    650:
    VAHGFANLLT | LDKKTLQEIL | LHYPTSKKLL | MKKAKILLSQ | KGKTTQAIPA | 
    694:
    RPGPAFLFPP | KEETPRMLKV | LLGNTGKVDL | GRLLKGKRKT | TTQK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    KEGG:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cyclic nucleotide-gated cation channel beta-3
    ELISA Kit for Mouse Cyclic nucleotide-gated cation channel beta-3
    ELISA Kit for Mouse Cyclic nucleotide-gated cation channel beta-3
    CLIA Kit for Mouse Cyclic nucleotide-gated cation channel beta-3
    CLIA Kit for Mouse Cyclic nucleotide-gated cation channel beta-3
    CLIA Kit for Mouse Cyclic nucleotide-gated cation channel beta-3
    Polyclonal Antibody for Mouse Cyclic nucleotide-gated cation channel beta-3
    Polyclonal Antibody for Mouse Cyclic nucleotide-gated cation channel beta-3
    Polyclonal Antibody for Mouse Cyclic nucleotide-gated cation channel beta-3
    Monoclonal Antibody for Mouse Cyclic nucleotide-gated cation channel beta-3
    Monoclonal Antibody for Mouse Cyclic nucleotide-gated cation channel beta-3
    Monoclonal Antibody for Mouse Cyclic nucleotide-gated cation channel beta-3
    Protein for Mouse Cyclic nucleotide-gated cation channel beta-3
    Protein for Mouse Cyclic nucleotide-gated cation channel beta-3
    Protein for Mouse Cyclic nucleotide-gated cation channel beta-3

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and functional characterization of a new modulatory cyclic nucleotide-gated channel subunit from mouse retina."
      Gerstner A. , Zong X. , Hofmann F. , Biel M.
      J. Neurosci.20:1324-1332(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBUNIT;TISSUE SPECIFICITY
      strain: C57BL/6.
      tissue: Retina.
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