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Index > Protein center > Cnr2(Gene name) > Mouse
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  • Cnr2 (Gene name),
  • Cannabinoid receptor 2 (Protein name ),  CNR2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cnr2;
    Protein name:
    Cannabinoid receptor 2(CB-2;CB2;mCB2);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein Cell projection dendrite Perikaryon Localizes to apical dendrite of pyramidal neurons.
    Protein Attributes:
    Sequence length:
    347
    Sequence:
    50:
    MEGCRETEVT | NGSNGGLEFN | PMKEYMILSS | GQQIAVAVLC | TLMGLLSALE | 
    100:
    NMAVLYIILS | SRRLRRKPSY | LFISSLAGAD | FLASVIFACN | FVIFHVFHGV | 
    150:
    DSNAIFLLKI | GSVTMTFTAS | VGSLLLTAVD | RYLCLCYPPT | YKALVTRGRA | 
    200:
    LVALCVMWVL | SALISYLPLM | GWTCCPSPCS | ELFPLIPNDY | LLGWLLFIAI | 
    250:
    LFSGIIYTYG | YVLWKAHRHV | ATLAEHQDRQ | VPGIARMRLD | VRLAKTLGLV | 
    300:
    LAVLLICWFP | ALALMGHSLV | TTLSDQVKEA | FAFCSMLCLV | NSMVNPIIYA | 
    347:
    LRSGEIRSAA | QHCLIGWKKY | LQGLGPEGKE | EGPRSSVTET | EADVKTT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CB-2
    Cat.:
    E10714r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse CB-2
    Cat.:
    E10714m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse CB-2
    Cat.:
    E10714h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse CB-2
    Cat.:
    U10714h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CB-2
    Cat.:
    U10714r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse CB-2
    Cat.:
    U10714m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse CB-2
    Cat.:
    P10714Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CB-2
    Cat.:
    P10714Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse CB-2
    Cat.:
    P10714Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse CB-2
    Monoclonal Antibody for Mouse CB-2
    Monoclonal Antibody for Mouse CB-2
    Protein for Mouse CB-2
    Protein for Mouse CB-2
    Protein for Mouse CB-2

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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular cloning, expression and function of the murine CB2 peripheral cannabinoid receptor."
      Shire D. , Calandra B. , Rinaldi-Carmona M. , Oustric D. , Pessegue B. , Cabanne O. , le Fur G. , Caput D. , Ferrara P.
      Biochim. Biophys. Acta1307:132-136(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
      strain: C57BL/6.
      tissue: Spleen.
    2. 2.
      "The genes encoding the peripheral cannabinoid receptor and alpha-L-fucosidase are located near a newly identified common virus integration site, Evi11."
      Valk P.J.M. , Hol S. , Vankan Y. , Ihle J.N. , Askew D. , Jenkins N.A. , Gilbert D.J. , Copeland N.G. , de Both N.J. , Loewenberg B. , Delwel R.
      J. Virol.71:6796-6804(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: NFS/N.
    3. 3.
      Buckley N.E. , Bonner T.I.
      Submitted (1995-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/Sv.
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Bone.
      tissue: Thymus.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    6. 6.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
    8. 8.
      "Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor."
      Buckley N.E. , McCoy K.L. , Mezey E. , Bonner T. , Zimmer A. , Felder C.C. , Glass M. , Zimmer A.
      Eur. J. Pharmacol.396:141-149(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    9. 9.
      "Hematopoietic cells expressing the peripheral cannabinoid receptor migrate in response to the endocannabinoid 2-arachidonoylglycerol."
      Jorda M.A. , Verbakel S.E. , Valk P.J.M. , Vankan-Berkhoudt Y.V. , Maccarrone M. , Finazzi-Agro A. , Loewenberg B. , Delwel R.
      Blood99:2786-2793(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    10. 10.
      "Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors."
      Casanova M.L. , Blazquez C. , Martinez-Palacio J. , Villanueva C. , Fernandez-Acenero M.J. , Huffman J.W. , Jorcano J.L. , Guzman M.
      J. Clin. Invest.111:43-50(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    11. 11.
      "Formation of B and T cell subsets require the cannabinoid receptor CB2."
      Ziring D. , Wei B. , Velazquez P. , Schrage M. , Buckley N.E. , Braun J.
      Immunogenetics58:714-725(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    14. 14.
      "Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells."
      Maresz K. , Pryce G. , Ponomarev E.D. , Marsicano G. , Croxford J.L. , Shriver L.P. , Ledent C. , Cheng X. , Carrier E.J. , Mann M.K. , Giovannoni G. , Pertwee R.G. , Yamamura T. , Buckley N.E. , Hillard C.J. , Lutz B. , Baker D. , Dittel B.N.
      Nat. Med.13:492-497(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    15. 15.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    16. 16.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-335; SER-336 AND THR-338;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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