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Index > Protein center > CRH(Gene name) > Human
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  • CRH (Gene name),
  • Corticoliberin (Protein name ),  CRF_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CRH;
    Protein name:
    Corticoliberin;
    Alternative:
    Corticotropin-releasing hormone;Corticotropin-releasing factor(CRF);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts (via C-terminus) with CRFR1 (via N-terminal extracellular domain).
    Function:
    This hormone from hypothalamus regulates the release of corticotropin from pituitary gland.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    196
    Sequence:
    50:
    MRLPLLVSAG | VLLVALLPCP | PCRALLSRGP | VPGARQAPQH | PQPLDFFQPP | 
    100:
    PQSEQPQQPQ | ARPVLLRMGE | EYFLRLGNLN | KSPAAPLSPA | SSLLAGGSGS | 
    150:
    RPSPEQATAN | FFRVLLQQLL | LPRRSLDSPA | ALAERGARNA | LGGHQEAPER | 
    196:
    ERRSEEPPIS | LDLTFHLLRE | VLEMARAEQL | AQQAHSNRKL | MEIIGK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    MIM:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Corticoliberin
    Cat.:
    E0835r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Corticoliberin
    Cat.:
    E0835p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Corticoliberin
    Cat.:
    E0835m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Corticoliberin
    Cat.:
    E0835h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Corticoliberin
    Cat.:
    E0835b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Corticoliberin
    Cat.:
    E0835d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Corticoliberin
    Cat.:
    U0835d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Corticoliberin
    Cat.:
    U0835p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Corticoliberin
    Cat.:
    U0835b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Corticoliberin
    Cat.:
    U0835h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Corticoliberin
    Cat.:
    U0835m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Corticoliberin
    Cat.:
    U0835r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Corticoliberin
    Polyclonal Antibody for Human Corticoliberin
    Cat.:
    P0835Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Corticoliberin
    Polyclonal Antibody for Human Corticoliberin
    Cat.:
    P0835Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Corticoliberin
    Cat.:
    P0835Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Corticoliberin
    Monoclonal Antibody for Human Corticoliberin
    Monoclonal Antibody for Human Corticoliberin
    Monoclonal Antibody for Human Corticoliberin
    Monoclonal Antibody for Human Corticoliberin
    Monoclonal Antibody for Human Corticoliberin
    Monoclonal Antibody for Human Corticoliberin
    Protein for Human Corticoliberin
    Protein for Human Corticoliberin
    Protein for Human Corticoliberin
    Cat.:
    R0835h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human Corticoliberin
    Protein for Human Corticoliberin
    Protein for Human Corticoliberin

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    References
    1. 1.
      "Isolation and sequence analysis of the human corticotropin-releasing factor precursor gene."
      Shibahara S. , Morimoto Y. , Furutani Y. , Notake M. , Takahashi H. , Shimizu S. , Horikawa S. , Numa S.
      EMBO J.2:775-779(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];AMIDATION AT ILE-194
    2. 2.
      "Preprocorticotropin releasing hormone: cDNA sequence and in vitro processing."
      Robinson B.G. , D'Angio L.A. Jr. , Pasieka K.B. , Majzoub J.A.
      Mol. Cell. Endocrinol.61:175-180(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
      Otsuki T. , Ota T. , Nishikawa T. , Hayashi K. , Suzuki Y. , Yamamoto J. , Wakamatsu A. , Kimura K. , Sakamoto K. , Hatano N. , Kawai Y. , Ishii S. , Saito K. , Kojima S. , Sugiyama T. , Ono T. , Okano K. , Yoshikawa Y. , more...
      DNA Res.12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Placenta.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    7. 7.
      "Isolation and characterization of a corticotropin-releasing hormone-like peptide from human placenta."
      Sasaki A. , Tempst P. , Liotta A.S. , Margioris A.N. , Hood L.E. , Kent S.B. , Sato S. , Shinkawa O. , Yoshinaga K. , Krieger D.T.
      J. Clin. Endocrinol. Metab.67:768-773(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 154-186
    8. 8.
      "Solution structure of human corticotropin releasing factor by 1H NMR and distance geometry with restrained molecular dynamics."
      Romier C. , Bernassau J.-M. , Cambillau C. , Darbon H.
      Protein Eng.6:149-156(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 154-194
    9. 9.
      "Molecular recognition of corticotropin-releasing factor by its G-protein-coupled receptor CRFR1."
      Pioszak A.A. , Parker N.R. , Suino-Powell K. , Xu H.E.
      J. Biol. Chem.283:32900-32912(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.96 ANGSTROMS) OF 175-194 IN COMPLEX WITH CRFR1;SUBUNIT;MUTAGENESIS OF GLN-183; ASN-187; ARG-188; LEU-190; MET-191 AND GLU-192
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