CCKBR ELISA Kit for Human(Homo sapiens) | EIAab.comCCKBR ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CCKBR(Gene name) > Human

CCKBR (Gene name),

Gastrin/cholecystokinin type B receptor (Protein name ), GASR_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CCKBR(CCKRB);

Protein name:

Gastrin/cholecystokinin type B receptor(CCK-B receptor;CCK-BR);

Alternative:

Cholecystokinin-2 receptor(CCK2-R);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

447

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

447:

CLETCARCCP | RPPRARPRAL | PDEDPPTPSI | ASLSRLSYTT | ISTLGPG

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P32239

MIM:

118445

UniGene:

Hs.203

KEGG:

hsa:887

Pfam:

PF00001

STRING:

9606.ENSP00000335544

SMR:

P32239

Uniprot:

P32239

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ELISA Kit for Human CCK-B receptor

Cat.:

E1051h

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96T

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ELISA Kit for Human CCK-B receptor

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E1051m

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96T

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ELISA Kit for Human CCK-B receptor

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ELISA Kit for Human CCK-B receptor

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E1051d

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96T

ELISA Kit for Human CCK-B receptor

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E1051b

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96T

ELISA Kit for Human CCK-B receptor

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E1051r

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96T

CLIA Kit for Human CCK-B receptor

Cat.:

U1051d

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96T

CLIA Kit for Human CCK-B receptor

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U1051r

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96T

CLIA Kit for Human CCK-B receptor

Cat.:

U1051b

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96T

CLIA Kit for Human CCK-B receptor

MSDS:

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CLIA Kit for Human CCK-B receptor

Cat.:

U1051m

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Packing:

96T

CLIA Kit for Human CCK-B receptor

Cat.:

U1051h

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96T

Polyclonal Antibody for Human CCK-B receptor

Cat.:

P1051Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human CCK-B receptor

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P1051Rb-m

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Polyclonal Antibody for Human CCK-B receptor

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P1051Rb-h

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Polyclonal Antibody for Human CCK-B receptor

Monoclonal Antibody for Human CCK-B receptor

Protein for Human CCK-B receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Molecular cloning of the human brain and gastric cholecystokinin receptor: structure, functional expression and chromosomal localization."
Pisegna J.R. , de Weerth A. , Huppi K. , Wank S.A.
Biochem. Biophys. Res. Commun.189:296-303(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain.
2.

"The human brain cholecystokinin-B/gastrin receptor. Cloning and characterization."
Lee Y.-M. , Beinborn M. , McBride E.W. , Lu M. , Kolakowski L.F. Jr. , Kopin A.S.
J. Biol. Chem.268:8164-8169(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain.
3.

"Functional characterization of a human brain cholecystokinin-B receptor. A trophic effect of cholecystokinin and gastrin."
Ito M. , Matsui T. , Taniguchi T. , Tsukamoto T. , Murayama T. , Arima N. , Nakata H. , Chiba T. , Chihara K.
J. Biol. Chem.268:18300-18305(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
tissue: Brain.
4.

"The human gastrin/cholecystokinin type B receptor gene: alternative splice donor site in exon 4 generates two variant mRNAs."
Song I. , Brown D.R. , Wiltshire R.N. , Gantz I. , Trent J.M. , Yamada T.
Proc. Natl. Acad. Sci. U.S.A.90:9085-9089(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Placenta.
5.

"Cholecystokinin stimulates Ca2+ mobilization and clonal growth in small cell lung cancer through CCKA and CCKB/gastrin receptors."
Herget T. , Sethi T. , Wu S.V. , Walsh J.H. , Rozengurt E.
Ann. N. Y. Acad. Sci.713:283-297(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
tissue: Fetal brain.
6.

"Functional characterization of two cholecystokinin-B/gastrin receptor isoforms: a preferential splice donor site in the human receptor gene."
Ito M. , Iwata N. , Taniguchi T. , Murayama T. , Chihara K. , Matsui T.
Cell Growth Differ.5:1127-1135(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];FUNCTION;ALTERNATIVE SPLICING;TISSUE SPECIFICITY
tissue: Lung fibroblast.
7.

"A truncated isoform of human CCK-B/gastrin receptor generated by alternative usage of a novel exon."
Miyake A.
Biochem. Biophys. Res. Commun.208:230-237(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);TISSUE SPECIFICITY
tissue: Stomach.
8.

"Human colorectal cancers express a constitutively active cholecystokinin-B/gastrin receptor that stimulates cell growth."
Hellmich M.R. , Rui X.-L. , Hellmich H.L. , Fleming R.Y.D. , Evers B.M. , Townsend C.M. Jr.
J. Biol. Chem.275:32122-32128(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION (ISOFORM 2);TISSUE SPECIFICITY
tissue: Colon cancer.
9.

"Identification of CCK-B/gastrin receptor splice variants in human peripheral blood mononuclear cells."
Schmitz F. , Schrader H. , Otte J.-M. , Schmitz H. , Stueber E. , Herzig K.-H. , Schmidt W.E.
Regul. Pept.101:25-33(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;ALTERNATIVE SPLICING
tissue: Peripheral blood.
10.

"Characterization of the CCK-C (cancer) receptor in human pancreatic cancer."
Smith J.P. , Verderame M.F. , McLaughlin P. , Martenis M. , Ballard E. , Zagon I.S.
Int. J. Mol. Med.10:689-694(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
tissue: Pancreatic cancer.
11.

"Cloning and expression of the human temporal cortex cholecystokinin B receptor."
Tate S.N. , Gray J. , Denyer J. , Stolz M. , Foord S. , Lee M.G.
Submitted (1996-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Temporal cortex.
12.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Stomach.
13.

"cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
Kopatz S.A. , Aronstam R.S. , Sharma S.V.
Submitted (2003-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
14.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
15.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Placenta.
16.

"An 84-kilobase physical map and repeat polymorphisms of the gastrin/cholecystokinin brain receptor region at the junction of chromosome segments 11p15.4 and 15.5."
O'Briant K.C. , Ali S.Y. , Weier H.-U.G. , Bepler G.
Chromosome Res.6:415-418(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 52-447
17.

"CCKA and CCKB receptors are expressed in small cell lung cancer lines and mediate Ca2+ mobilization and clonal growth."
Sethi T. , Herget T. , Wu S.V. , Walsh J.H. , Rozengurt E.
Cancer Res.53:5208-5213(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 244-333 (ISOFORMS 1/3);FUNCTION
tissue: Fetal brain.
18.

"Localization of the human cholecystokinin-B/gastrin receptor gene (CCKBR) to chromosome 11p15.5-->p15.4 by fluorescence in situ hybridization."
Zimonjic D.B. , Popescu N.C. , Matsui T. , Ito M. , Chihara K.
Cytogenet. Cell Genet.65:184-185(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL LOCATION
19.

"Intermolecular interactions between cholecystokinin-8 and the third extracellular loop of the cholecystokinin-2 receptor."
Giragossian C. , Mierke D.F.
Biochemistry41:4560-4566(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 352-379

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